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WIN 51,708

Name: WIN 51,708
Brand: TargetMol
SKU: T29157
Price: 293 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T29157Cas No. 144177-30-0

Alias WIN-51,708, WIN51,708

WIN 51,708 is a neurokinin receptor (NK1) antagonist.

WIN 51,708

🥰Excellent

Purity: 99%

Catalog No. T29157Alias WIN-51,708, WIN51,708Cas No. 144177-30-0

WIN 51,708 is a neurokinin receptor (NK1) antagonist.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$293	In Stock	In Stock
2 mg	$436	In Stock	In Stock
5 mg	$722	In Stock	In Stock
10 mg	$987	In Stock	In Stock
25 mg	$1,520	In Stock	In Stock
50 mg	$1,980	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Purity:99%

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Product Introduction

Bioactivity

Description	WIN 51,708 is a neurokinin receptor (NK1) antagonist.
In vivo	Systemic injection of the nonpeptide neurokinin-1 receptor antagonist WIN-51,708 (5 mg/kg, IP) into male mice that crossed the blood-brain barrier 30 minutes before METH significantly attenuated METH-induced 3-NT striatal production as measured by HPLC. [1]
Synonyms	WIN-51,708, WIN51,708

Chemical Properties

Molecular Weight	439.59
Formula	C₂₉H₃₃N₃O
Cas No.	144177-30-0
Smiles	C[C@@]12[C@@]3([C@]([C@]4([C@](C)(CC3)[C@@](C#C)(O)CC4)[H])(CC[C@]1(CC=5C(C2)=CN6C(N5)=NC=7C6=CC=CC7)[H])[H])[H]
Relative Density.	1.31g/cm3
Color	Yellow
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

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