Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Seganserin, a non-selective 5-hydroxytryptamine 2-HT receptor antagonist, reversed the inhibitory effects of fluoxetine and quipazine on luteinizing hormone-induced hyperphagia, depression and nociception, and reversed the antidepressant and analgesic effects induced by fluoxetine and quipazine.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 195.00 | |
5 mg | In stock | $ 430.00 | |
10 mg | In stock | $ 636.00 | |
25 mg | In stock | $ 987.00 | |
50 mg | In stock | $ 1,360.00 | |
100 mg | In stock | $ 1,830.00 | |
500 mg | In stock | $ 3,680.00 |
Description | Seganserin, a non-selective 5-hydroxytryptamine 2-HT receptor antagonist, reversed the inhibitory effects of fluoxetine and quipazine on luteinizing hormone-induced hyperphagia, depression and nociception, and reversed the antidepressant and analgesic effects induced by fluoxetine and quipazine. |
In vivo |
Seganserin (2 mg/kg, i.p.; mice), a 5-HT(2) receptor antagonist pretreatment significantly reversed fluoxetine and quipazine-induced antidepressant and analgesic effects.[2] Seganserin (2 mg/kg, i.p.; mice), significantly reversed the suppressive effect of fluoxetine and quipazine on progesterone-induced hyperphagia, depression, and algesia in the hot-plate test.[2] |
Molecular Weight | 471.54 |
Formula | C29H27F2N3O |
CAS No. | 87729-89-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 55 mg/mL (116.64 mM)
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Seganserin 87729-89-3 GPCR/G Protein Neuroscience 5-HT Receptor inhibitor inhibit