μ-opr

OPR-003 is a human monoclonal antibody that targets IL-6. [OPR-003] is applicable in research related to hematologic malignancies and rheumatoid arthritis.

Vopratelimab (JTX-2011) is a selective humanized immunoglobulin G1-kappa monoclonal antibody and a potent ICOS agonist with high affinity for inducible T cell co-stimulating factors (ICOS), showing affinities of 0.93 nM for hICOS, 3.7 nM for rat ICOS, and 0.64 nM for mICOS. It exhibits anti-tumor immune effects and can improve metastatic non-small cell lung cancer.

Alunacedase alfa (APN-01) is a soluble angiotensin-converting enzyme 2 (hrsACE2) with antiviral activity that reduces the competitive entry of SARS-CoV-2 into cell membranes bound to ACE2. alunacedase alfa mimics ACE2 in vivo and can be used to study novel coronavirus infections, pulmonary hypertension and acute lung injury. Alunacedase alfa mimics ACE2 in vivo and can be used to study novel coronavirus infections, pulmonary hypertension and acute lung injury.

Coprelotamab (GB-221) is an IgG-κ monoclonal antibody that targets EGFR2, commonly produced in CHO DG44 (Chinese Hamster Ovary) cells [1].

Tulinercept (OPRX-106), a monoclonal antibody, may be utilized in a range of biochemical research applications [1].

Torapsel (42-89-glycoprotein; WAY164339), a fusion protein comprising immunoglobulin, is utilized for the investigation of ischemia-reperfusion injury prophylaxis.

Tegoprubart is an investigational anti-CD40L monoclonal antibody that functions by potently inhibiting the CD40-CD40L costimulatory signaling pathway, thereby resulting in a reduction of both cellular and humoral immune responses, as well as the promotion of immunological tolerance, with preclinical data demonstrating significant efficacy in transplant models.

Eglatoprutug is a humanized immunoglobulin G1-kappa monoclonal antibody targeting the c-Kit receptor [1].

Anselamimab is a humanized IgG1κ monoclonal antibody targeting serum amyloid A1 (SAA1). It removes amyloid deposits by specifically binding to amyloid fibrils and triggering phagocytosis by macrophages and neutrophils.Anselamimab was used as an APP(β-amyloid A4 Protein Precursor ) inhibitor in the clinical phase for the treatment of light chain (AL) amyloidosis.

Anti-Mouse Podoplanin/glycoprotein 38 Antibody (8.1.1) is an IgG antibody inhibitor derived from Syrian hamsters that targets mouse Podoplanin/glycoprotein 38.

Omoprubart is a humanized IgG2-G4 κ monoclonal antibody that targets C5.

Budoprutug is a human-derived IgG1κ monoclonal antibody targeting CD19. The isotype control product for Budoprutug is HumanIgG1kappa, Isotype Control.

Vopratelimab (MouseIgG2a) is a monoclonal antibody that selectively targets the inducible T-cell co-stimulator (ICOS). The variable region of Vopratelimab (MouseIgG2a) matches that of Vopratelimab, while its constant region is based on the mouse IgG2a sequence. Vopratelimab (MouseIgG2a) promotes anti-tumor immune responses and enhances the efficacy of combination therapy with anti-PD-1.

The Anti-LCMV Nucleoprotein Antibody (VL-4) is a mouse-derived IgG2akappa antibody that targets the LCMV nucleoprotein and originates from rats. The isotype control for this antibody is RatIgG2akappa, Isotype Control.

Ipsoprubart is a humanized IgG1κ antibody targeting SIRPa/CD172a, with its corresponding isotype control being HumanIgG1kappa, Isotype Control.

Zadoprubart is a humanized IgG4κ monoclonal antibody targeting BTLA, with the corresponding isotype control being HumanIgG4(S228P) kappa, Isotype Control.

Imeroprubart is a humanized IgG1λ2 monoclonal antibody that specifically targets FCGRT. The corresponding isotype control for this compound is labeled as HumanIgG1lambda2, Isotype Control.

Ruxoprubart is a humanized IgG1κ monoclonal antibody targeting CFB, with HumanIgG1kappa, Isotype Control serving as its corresponding isotype control.

Anti-AcmNPV Envelope glycoprotein gp64/AcmNPV-gp64 Antibody (9B642) is a Mouse IgG1 monoclonal antibody targeting AcMNPV AcmNPV Envelope glycoprotein gp64/AcmNPV-gp64.

Anti-Human respiratory syncytial virus (RSV) Fusion Glycoprotein/RSV-F Antibody (1B191) is a Rabbit IgG monoclonal antibody targeting RSV Human respiratory syncytial virus (RSV) Fusion Glycoprotein/RSV-F.