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Docarpamine is an orally active dopamine prodrug that is converted into active dopamine in the small intestine and liver through hydroxylation. In situations of spontaneous hypertension, it primarily activates peripheral D1-like receptors (D1-like receptor) to lower blood pressure and heart rate. Under normal blood pressure conditions, Docarpamine exhibits pressor effects and tachycardia by activating D1-like receptors, vasopressin V1 receptors (vasopressin V1 receptor), and α-adrenergic receptors (α-adrenergic receptor). Docarpamine is useful for studying renal vasodilation and diuresis.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 10 mg | Inquiry | 10-14 weeks | 10-14 weeks | |
| 50 mg | Inquiry | 10-14 weeks | 10-14 weeks |
| Description | Docarpamine is an orally active dopamine prodrug that is converted into active dopamine in the small intestine and liver through hydroxylation. In situations of spontaneous hypertension, it primarily activates peripheral D1-like receptors (D1-like receptor) to lower blood pressure and heart rate. Under normal blood pressure conditions, Docarpamine exhibits pressor effects and tachycardia by activating D1-like receptors, vasopressin V1 receptors (vasopressin V1 receptor), and α-adrenergic receptors (α-adrenergic receptor). Docarpamine is useful for studying renal vasodilation and diuresis. |
| Molecular Weight | 470.54 |
| Formula | C21H30N2O8S |
| Cas No. | 74639-40-0 |
| Smiles | O(C(OCC)=O)C1=C(OC(OCC)=O)C=C(CCNC([C@H](CCSC)NC(C)=O)=O)C=C1 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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