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Anti-CDV Fusion glycoprotein F0 Antibody (4S488)
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Catalog No. TMAB-04191
Anti-CDV Fusion glycoprotein F0 Antibody (4S488) is a Mouse antibody targeting CDV Fusion glycoprotein F0. Anti-CDV Fusion glycoprotein F0 Antibody (4S488) can be used in WB,ELISA.
Anti-CDV Fusion glycoprotein F0 Antibody (4S488)
Anti-CDV Fusion glycoprotein F0 Antibody (4S488)
😃Good
Catalog No. TMAB-04191
Anti-CDV Fusion glycoprotein F0 Antibody (4S488) is a Mouse antibody targeting CDV Fusion glycoprotein F0. Anti-CDV Fusion glycoprotein F0 Antibody (4S488) can be used in WB,ELISA.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 200 μg | $1,060 | 7-10 days | 7-10 days | |
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-CDV Fusion glycoprotein F0 Antibody (4S488) is a Mouse antibody targeting CDV Fusion glycoprotein F0. Anti-CDV Fusion glycoprotein F0 Antibody (4S488) can be used in WB,ELISA. |
| Ig Type | IgG |
| Clone | 4S488 |
| Reactivity | CDV |
| Application | |
| Recommended Dose | WB: 1:500-2000; ELISA: 1:5000-10000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Class I viral fusion protein. Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and plasma cell membrane fusion, the heptad repeat (HR) regions assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and plasma cell membranes. Directs fusion of viral and cellular membranes leading to delivery of the nucleocapsid into the cytoplasm. This fusion is pH independent and occurs directly at the outer cell membrane. The trimer of F1-F2 (F protein) probably interacts with H at the virion surface. Upon HN binding to its cellular receptor, the hydrophobic fusion peptide is unmasked and interacts with the cellular membrane, inducing the fusion between cell and virion membranes. Later in infection, F proteins expressed at the plasma membrane of infected cells could mediate fusion with adjacent cells to form syncytia, a cytopathic effect that could lead to tissue necrosis |
| Immunogen | Recombinant Protein: Canine distemper virus Fusion glycoprotein F0 |
| Gene Name | F |
| Protein Name | Fusion glycoprotein F0 |
| Molecular Weight | Theoretical: 73 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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