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Anti-Fetuin A Antibody (4Z328)
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Catalog No. TMAY-00603
Alias α-2-HS-glycoprotein, alpha-2-HS-glycoprotein
Anti-Fetuin A Antibody (4Z328) is a Mouse antibody targeting Fetuin A. Anti-Fetuin A Antibody (4Z328) can be used in ELISA,ELISA(Cap).
Anti-Fetuin A Antibody (4Z328)
Anti-Fetuin A Antibody (4Z328)
😃Good
Catalog No. TMAY-00603Alias α-2-HS-glycoprotein, alpha-2-HS-glycoprotein
Anti-Fetuin A Antibody (4Z328) is a Mouse antibody targeting Fetuin A. Anti-Fetuin A Antibody (4Z328) can be used in ELISA,ELISA(Cap).
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 20 μL | $70 | 7-10 days | |
| 100 μL | $199 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Mouse Monoclonal Application: ELISA, ELISA(Cap) Reactivity: Human |
| Alias | α-2-HS-glycoprotein, alpha-2-HS-glycoprotein |
| Ig Type | Mouse IgG1 |
| Clone | 4Z328 |
| Reactivity | Human |
| Application | ELISA,ELISA(Cap) |
| Recommended Dose | ELISA: 1:1000-1:2000; ELISA(Cap): 1:250-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Fetuin-A / AHSG (rhFetuin-A; TMPY-00801; NP_001613.2; Met 1-Val 367). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Fetuin-A, also known as Alpha-2-HS-Glycoprotein (AHSG), belongs to the Fetuin family, is a plasma binding protein, and is more abundant in fetal than adult blood. It is involved in several functions, such as endocytosis, brain development and the formation of bone tissue. Fetuins are carrier proteins like albumin. Fetuin-A forms soluble complexes with calcium and phosphate and thus is a carrier of otherwise insoluble calcium phosphate. Thus Fetuin-A is a potent inhibitor of pathological calcification. The circulating levels of fetuin-A, a well-described inhibitor of calcification, regulate the cell-dependent process of osteogenesis. The low circulating fetuin-A levels are associated with a greater prevalence and/or severity of Vascular calcification (VC) and increased risk for all-cause and cardiovascular mortality. However, high circulating fetuin-A levels appear to induce insulin resistance and, in non-dialyzed subjects with diabetic nephropathy, are directly related to VC burden. The emerging role of fetuin-A deficiency as a risk factor in dialysis patients was documented in cross-sectional studies demonstrating a significant correlation with all-cause and cardiovascular mortality. Additionally, Human fetuin-A is a negative acute phase protein involved in inflammatory diseases, thus being a potential physiological regulator of meprin activity. Fetuin-A is a broad-range protease inhibitor. Fetuin-A and cystatin C as endogenous proteolytic regulators of meprin activity broadens our understanding of the proteolytic network in plasma. |
| Conjucates | Unconjugated |
| Immunogen | Human cell-derived Fetuin-A protein (TMPY-00801) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
Sci Citations
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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