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Anti-FSTL3 Antibody (6R403)
😃Good
Catalog No. TMAY-03044
Alias follistatin-like 3 (secreted glycoprotein), Flrg, E030038F23Rik
Anti-FSTL3 Antibody (6R403) is a Rabbit antibody targeting FSTL3. Anti-FSTL3 Antibody (6R403) can be used in ELISA.
Anti-FSTL3 Antibody (6R403)
Anti-FSTL3 Antibody (6R403)
😃Good
Catalog No. TMAY-03044Alias follistatin-like 3 (secreted glycoprotein), Flrg, E030038F23Rik
Anti-FSTL3 Antibody (6R403) is a Rabbit antibody targeting FSTL3. Anti-FSTL3 Antibody (6R403) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $269 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Rabbit Monoclonal Application: ELISA Reactivity: Mouse |
| Alias | follistatin-like 3 (secreted glycoprotein), Flrg, E030038F23Rik |
| Ig Type | Rabbit IgG |
| Clone | 6R403 |
| Reactivity | Mouse |
| Application | ELISA |
| Recommended Dose | ELISA: 1:5000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse FLRG / Fstl3 (rM FLRG / Fstl3; TMPY-00975; NP_113557.1; Met 1-Val 256). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Follistatin-like 3 (FLRG/Fstl3) is a secreted glycoprotein of the follistatin-module-protein family. It may have a role in leukemogenesis. FLRG/Fstl3 is a recently described member of the FST family having an overall structure and activity profile similar to that of FST, including binding and neutralization of activin. FLRG/Fstl3 is expressed in a wide range of adult tissues, not detected in hematopoietic cells except in patients with a B cell chronic leukemia and a translocation. Isoform 1 or the secreted form is a binding and antagonizing protein for members of the TGF-beta family, such us activin, BMP2 and MSTN. Inhibits activin A-, activin B-, BMP2- and MSDT-induced cellular signaling; more effective on activin A than on activin B. Involved in bone formation; inhibits osteoclast differentiation. Involved in hematopoiesis; involved in differentiation of hemopoietic progenitor cells, increases hematopoietic cell adhesion to fibronectin and seems to contribute to the adhesion of hematopoietic precursor cells to the bone marrow stroma. Isoform 2 of FLRG/Fstl3 or the nuclear form of FLRG/Fstl3 is probably involved in transcriptional regulation via interaction with MLLT10. Modulation of activin and other TGFβ superfamily signaling is the primary mechanism of action for both follistatin (FS) and FS-like 3 (FSTL-3). FLRG/Fstl3 is likely to be a local regulator of activin action in gonadal development and gametogenesis and, further, that activin appears to have important actions in gonadal development and function that are critical for normal reproduction. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Mouse FLRG protein (TMPY-00975) |
| Antigen Species | Mouse |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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