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Anti-LDLR Antibody-FITC (3N325)

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Catalog No. TMAY-03221F
Alias low density lipoprotein receptor, LDLCQ2, LDL Receptor, LDL R, FHC, FH

Anti-LDLR Antibody-FITC (3N325) is a FITC-conjugated Rabbit antibody targeting LDLR. Anti-LDLR Antibody-FITC (3N325) can be used in FCM.

Anti-LDLR Antibody-FITC (3N325)

Anti-LDLR Antibody-FITC (3N325)

😃Good
Catalog No. TMAY-03221FAlias low density lipoprotein receptor, LDLCQ2, LDL Receptor, LDL R, FHC, FH
Anti-LDLR Antibody-FITC (3N325) is a FITC-conjugated Rabbit antibody targeting LDLR. Anti-LDLR Antibody-FITC (3N325) can be used in FCM.
Pack SizePriceAvailabilityQuantity
25 T$104 7-10 days
100 T$211 7-10 days
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Product Introduction

Bioactivity
Description
Anti-LDLR Antibody-FITC (3N325) is a FITC-conjugated Rabbit antibody targeting LDLR. Anti-LDLR Antibody-FITC (3N325) can be used in FCM.
Aliaslow density lipoprotein receptor, LDLCQ2, LDL Receptor, LDL R, FHC, FH
Ig Type
Monoclonal Rabbit IgG
Clone
3N325
Reactivity
Mouse
Verified Activity
Profile of anti-LDLR reactivity on Raw264.7 cells analyzed by flow cytometry. Cells should be Fc-blocked by treatment with Mouse BD Fc Block™ purified anti-CD16/CD32 mAb 2.4G2 prior to staining, washed, then stained with FITC Rabbit anti-LDLR.
Application
FCM
Recommended Dose
10 μl/Test, 0.1 mg/ml
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Mouse LDLR / LDL Receptor (rM LDLR / LDL Receptor; TMPY-01014; NP_034830.2; Met 1-Arg 790) and conjugated with FITC under optimum conditions, the unreacted FITC was removed.
PurificationProtein A
AppearanceLiquid
FormulationPBS solution containing 0.5% BSA and 0.03%ProClin300
Research BackgroundLDL Receptor, also known as LDLR, is a mosaic protein that belongs to the Low-density lipoprotein receptor gene family. The low-density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. LDL Receptor consists of 840 amino acids (after removal of signal peptide) and mediates the endocytosis of cholesterol-rich LDL. Low-density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. LDL Receptor is a cell-surface receptor that recognizes the apoprotein B100 which is embedded in the phospholipid outer layer of LDL particles. The receptor also recognizes the apoE protein found in chylomicron remnants and VLDL remnants.
Related Conjugates and Formulations
Conjucates
FITC
Others Formats
Unconjugated/PerCP/PE
Antibody Types Available
4
Antigen Details
Immunogen
Recombinant Mouse LDLR / LDL Receptor protein (TMPY-01014)
Antigen Species
Mouse
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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