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Terazosin hydrochloride (Hytrin) , a selective alpha1-antagonist, can treat the benign prostatic hyperplasia (BPH). It also can lower blood pressure, so it is a drug of choice for patients with prostate enlargement and hypertension. It works on the smooth muscle of the bladder and the blood vessel walls by blocking the function of adrenaline.

Verapamil hydrochloride (Verapamil HCl) is a calcium channel blocker that is a class IV anti-arrhythmia agent.

Prazosin hydrochloride (Vasoflex) reduces peripheral resistance and relaxes vascular smooth muscles as a selective adrenergic alpha-1 antagonist by a mechanism not completely known. Prazosin hydrochloride is a synthetic piperazine derivative with hypotensive antiadrenergic properties, It is used in the treatment of heart failure, hypertension, pheochromocytoma, Raynaud's syndrome, prostatic hypertrophy, and urinary retention.

Verapamil (CP-16533-1) is a calcium channel blocker and an orally active and effective inhibitor of P-gp. Verapamil inhibits CYP3A4 and can be used in studies about the treatment of high blood pressure, heart arrhythmias, and angina research.

Nadolol is a non-selective beta-adrenergic antagonist with antihypertensive and antiarrhythmic activities. Nadolol competitively blocks beta-1 adrenergic receptors located in the heart and vascular smooth muscle, inhibiting the activities of the catechola

SBC-110736 is an inhibitor of proprotein convertase subtilisin kexin type 9 (PCSK9).

Methyclothiazide (Aquatensen) is a substituted benzothiadiazide, used to treat high blood pressure and fluid retention caused by various conditions including heart disease.

Terazosin hydrochloride dihydrate (Heitrin dihydrate) is a selective α1-adrenoceptor antagonist, used for treatment of symptoms of an enlarged prostate (BPH).

28-High Brassinolide is a naturally occurring compound that functions as a synthetic plant growth regulator and brassinosteroid (BR) analog. 28-High Brassinolide is utilized in plant life sciences due to its high binding affinity for the BRI1 receptor in plants.

Silica gel, high-purity grade, 220-440 mesh, is a rigid three-dimensional network of colloidal silicon dioxide suitable for drug delivery.

High density lipoprotein (HDL) (human) is a functional lipoprotein capable of binding to receptors such as scavenger receptor B1 (SR-B1), ABCA1, and ABCG1. It facilitates the removal of excess cholesterol from peripheral tissues through reverse cholesterol transport (RCT), transferring it to the liver for metabolism. Additionally, it activates endothelial nitric oxide synthase (eNOS) to produce nitric oxide (NO), offering antioxidant, anti-inflammatory, and vascular endothelial protection. High density lipoprotein (human) is a potential candidate for cardiovascular disease research, including atherosclerosis.

Elastase (high purity) is a serine protease that hydrolyzes proteins and peptides.

Dextran sulfate, high sulfate (MW 5000), is a sulfated polysaccharide that functions as a biopolymer. It exhibits antiviral, antibacterial, anti-inflammatory, antifibrotic, and wound-healing properties. Additionally, dextran sulfate can be utilized as an additive in cell culture media to prevent cell aggregation and serves as a gelling agent in cosmetics.

Porcine skin Gelatin, high gel strength, can be used for coating cells to enhance cell adhesion.

60 kcal% High Fat Diet is a high-fat model feed used for developing animal models of obesity and type II diabetes.

The 45 kcal% High Fat Diet is a type of high-fat model feed designed to induce obesity and type 2 diabetes in animal models.

Type XI collagen, highly purified and derived from human sternal cartilage (Human Type XI collagen, immunization grade), serves as an immunization-grade protein capable of inducing specific antibody production against this collagen in animals. Additionally, collagen functions as a hydrolytic substrate for MMP.

Type V collagen, highly purified from human placenta (Human Placenta Type V collagen, immunization grade), is a form of collagen protein that induces an immune response in animals, leading to the production of specific antibodies against this collagen. It also serves as a substrate for matrix metalloproteinases (MMP).

Human Amnion Type V collagen (immunization grade) is a highly purified form of collagen derived from human amnion. It has the ability to stimulate the immune system of animals to produce antibodies specific to this collagen. Additionally, this collagen serves as a hydrolytic substrate for MMP (matrix metalloproteinases).

Human Type III collagen, derived from human placenta (immunization grade), is a highly purified compound capable of eliciting an immune response in animals to produce specific antibodies against this collagen protein. Additionally, this collagen serves as a substrate for the hydrolysis by matrix metalloproteinases (MMPs).

Human Type I collagen, derived from highly purified human placenta and classified as immunization grade, stimulates the animal immune system to produce specific antibodies against this collagen. Additionally, collagen serves as a hydrolytic substrate for MMP (Matrix Metalloproteinases).

RMC-9805 is a novel, mutant-selective, covalent and oral KRASG12D (ON) inhibitor. A stable and high affinity triple complex is formed between RMC-9805, KRASG12D, and cyclophilin A, which inhibits signal transduction downstream of KRASG12D (ON) by disrupting its interaction with downstream effectors. RMC-9805 can induce cell apoptosis and promote tumor regression in preclinical KRASG12D tumor models. With rich experience in compound synthesis, we can provide fast customized synthesis services for this product according to your research needs.

Trastuzumab is a humanized monoclonal antibody for patients with invasive breast cancers that overexpress HER2. Trastuzumab has been clinically used to treat HER2 Positive Metastatic Breast Cancer and HER2 Positive Gastric Cancer.

5-HT1A modulator 1 exhibits high affinities for the 5-HT1A, α1-adrenergic receptor, and D2 receptor (IC50s = 2 nM, 10 nM, and 40 nM).