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Anti-KLK5/Kallikrein 5 Antibody

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Catalog No. T9901A-1476 Copy Product Info
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Anti-KLK5/Kallikrein 5 Antibody represents a highly specialized monoclonal or bispecific antibody specifically engineered to target the human kallikrein-related peptidase 5 with exceptional binding affinity and selectivity, effectively facilitating the measurable inhibition of excessive epidermal proteolytic activity across various preclinical experimental models to evaluate the restoration of the skin barrier function and the suppression of pro-inflammatory signaling pathways during strictly monitored laboratory observation periods to ensure high experimental sensitivity and accuracy in specialized research environments.
Anti-KLK5/Kallikrein 5 Antibody
Pack SizePriceUSA StockGlobal StockQuantity
1 mg$398InquiryInquiry
5 mg$1,190InquiryInquiry
10 mg$1,890InquiryInquiry
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-KLK5/Kallikrein 5 Antibody represents a highly specialized monoclonal or bispecific antibody specifically engineered to target the human kallikrein-related peptidase 5 with exceptional binding affinity and selectivity, effectively facilitating the measurable inhibition of excessive epidermal proteolytic activity across various preclinical experimental models to evaluate the restoration of the skin barrier function and the suppression of pro-inflammatory signaling pathways during strictly monitored laboratory observation periods to ensure high experimental sensitivity and accuracy in specialized research environments.
In vitro
In biochemical assays using recombinant human KLK5, Anti-KLK5/Kallikrein 5 Antibody bound the 170s loop and inhibited protease activity. In human skin models, it blocked IL-8 and TSLP expression [1].
In vivo
In KLK5-transgenic mouse models, systemic administration of Anti-KLK5/Kallikrein 5 Antibody reduced skin desquamation and erythroderma while lowering transepidermal water loss [1].
Reactivity
Human
Application
FACS
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Uniprot ID
TargetKLK5/Kallikrein5
Antibody Information
IsotypeIgG1
Storage & Solubility Information
StorageStore at low temperature Store at -20°C Shipping with blue ice/Shipping at ambient temperature.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: Anti-KLK5/Kallikrein 5 Antibody chemical structure | Anti-KLK5/Kallikrein 5 Antibody in vivo | Anti-KLK5/Kallikrein 5 Antibody in vitro