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Anti-KLK5/Kallikrein 5 Antibody

🥰Excellent
Catalog No. T9901A-1476

Anti-KLK5/Kallikrein 5 Antibody represents a highly specialized monoclonal or bispecific antibody specifically engineered to target the human kallikrein-related peptidase 5 with exceptional binding affinity and selectivity, effectively facilitating the measurable inhibition of excessive epidermal proteolytic activity across various preclinical experimental models to evaluate the restoration of the skin barrier function and the suppression of pro-inflammatory signaling pathways during strictly monitored laboratory observation periods to ensure high experimental sensitivity and accuracy in specialized research environments.

Anti-KLK5/Kallikrein 5 Antibody

Anti-KLK5/Kallikrein 5 Antibody

🥰Excellent
Catalog No. T9901A-1476
Anti-KLK5/Kallikrein 5 Antibody represents a highly specialized monoclonal or bispecific antibody specifically engineered to target the human kallikrein-related peptidase 5 with exceptional binding affinity and selectivity, effectively facilitating the measurable inhibition of excessive epidermal proteolytic activity across various preclinical experimental models to evaluate the restoration of the skin barrier function and the suppression of pro-inflammatory signaling pathways during strictly monitored laboratory observation periods to ensure high experimental sensitivity and accuracy in specialized research environments.
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Product Introduction

Bioactivity
Description
Anti-KLK5/Kallikrein 5 Antibody represents a highly specialized monoclonal or bispecific antibody specifically engineered to target the human kallikrein-related peptidase 5 with exceptional binding affinity and selectivity, effectively facilitating the measurable inhibition of excessive epidermal proteolytic activity across various preclinical experimental models to evaluate the restoration of the skin barrier function and the suppression of pro-inflammatory signaling pathways during strictly monitored laboratory observation periods to ensure high experimental sensitivity and accuracy in specialized research environments.
In vitro
In biochemical assays using recombinant human KLK5, Anti-KLK5/Kallikrein 5 Antibody bound the 170s loop and inhibited protease activity. In human skin models, it blocked IL-8 and TSLP expression [1].
In vivo
In KLK5-transgenic mouse models, systemic administration of Anti-KLK5/Kallikrein 5 Antibody reduced skin desquamation and erythroderma while lowering transepidermal water loss [1].
Reactivity
Human
Application
FACS
Functional assay
Antibody Type
Monoclonal
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Uniprot ID
TargetKLK5/Kallikrein5
Chemical Properties
Antibody Information
IsotypeIgG1
Storage & Solubility Information
Storagestore at low temperature | -20°C for 2 years, 4°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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