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Anti-PACAP38 Antibody

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Catalog No. T9901A-1283

Anti-PACAP38 Antibody represents a highly specialized monoclonal antibody specifically engineered to target the human pituitary adenylate cyclase-activating polypeptide 38 isoform with exceptional binding affinity and selectivity, effectively facilitating the measurable neutralization of ligand-mediated signaling within the GPCR/G Protein pathway to evaluate its functional role in neurovascular regulation during strictly monitored laboratory observation periods and functional cyclic AMP accumulation assays to ensure high experimental sensitivity.

Anti-PACAP38 Antibody

Anti-PACAP38 Antibody

Copy Product Info
🥰Excellent
Catalog No. T9901A-1283
Anti-PACAP38 Antibody represents a highly specialized monoclonal antibody specifically engineered to target the human pituitary adenylate cyclase-activating polypeptide 38 isoform with exceptional binding affinity and selectivity, effectively facilitating the measurable neutralization of ligand-mediated signaling within the GPCR/G Protein pathway to evaluate its functional role in neurovascular regulation during strictly monitored laboratory observation periods and functional cyclic AMP accumulation assays to ensure high experimental sensitivity.
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Product Introduction

Bioactivity
Description
Anti-PACAP38 Antibody represents a highly specialized monoclonal antibody specifically engineered to target the human pituitary adenylate cyclase-activating polypeptide 38 isoform with exceptional binding affinity and selectivity, effectively facilitating the measurable neutralization of ligand-mediated signaling within the GPCR/G Protein pathway to evaluate its functional role in neurovascular regulation during strictly monitored laboratory observation periods and functional cyclic AMP accumulation assays to ensure high experimental sensitivity.
Targets&IC50
PACAP:2.3 pM (Kd)
In vitro
In cell-based reporter assays, Anti-PACAP38 Antibody (ALD1910) potently neutralized PACAP38-induced cAMP production with high affinity [1].
In vivo
In rat models of vasodilation, systemic administration of Anti-PACAP38 Antibody (ALD1910) significantly inhibited PACAP38-induced increases in meningeal blood flow [1].
Reactivity
Human
Application
FACS
Functional assay
Antibody Type
Monoclonal
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Uniprot ID
TargetPACAP38
Chemical Properties
Antibody Information
IsotypeIgG1
Storage & Solubility Information
Storagestore at low temperature | -20°C for 2 years, 4°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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