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Anti-PACAP38 Antibody
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Catalog No. T9901A-1283 Copy Product Info
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Anti-PACAP38 Antibody represents a highly specialized monoclonal antibody specifically engineered to target the human pituitary adenylate cyclase-activating polypeptide 38 isoform with exceptional binding affinity and selectivity, effectively facilitating the measurable neutralization of ligand-mediated signaling within the GPCR/G Protein pathway to evaluate its functional role in neurovascular regulation during strictly monitored laboratory observation periods and functional cyclic AMP accumulation assays to ensure high experimental sensitivity.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $286 | Inquiry | Inquiry | |
| 5 mg | $985 | Inquiry | Inquiry | |
| 10 mg | $1,690 | Inquiry | Inquiry |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
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Antibody Information
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| Description | Anti-PACAP38 Antibody represents a highly specialized monoclonal antibody specifically engineered to target the human pituitary adenylate cyclase-activating polypeptide 38 isoform with exceptional binding affinity and selectivity, effectively facilitating the measurable neutralization of ligand-mediated signaling within the GPCR/G Protein pathway to evaluate its functional role in neurovascular regulation during strictly monitored laboratory observation periods and functional cyclic AMP accumulation assays to ensure high experimental sensitivity. |
| Targets & IC50 | PACAP:2.3 pM (Kd) |
| In vitro | In cell-based reporter assays, Anti-PACAP38 Antibody (ALD1910) potently neutralized PACAP38-induced cAMP production with high affinity [1]. |
| In vivo | In rat models of vasodilation, systemic administration of Anti-PACAP38 Antibody (ALD1910) significantly inhibited PACAP38-induced increases in meningeal blood flow [1]. |
| Reactivity | Human |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Uniprot ID | |
| Target | PACAP38 |
| Isotype | IgG1 |
| Storage | Store at low temperature Store at -20°C Shipping with blue ice/Shipping at ambient temperature. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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Related Tags: Anti-PACAP38 Antibody chemical structure | Anti-PACAP38 Antibody in vivo | Anti-PACAP38 Antibody in vitro
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