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ART5803

Catalog No. T9901A-1811 Copy Product Info
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ART5803 is a humanized IgG1 monoclonal antibody inhibitor targeting NMDAR. It binds with high affinity to the N-terminal domain (NTD) of the NMDAR GluN1 subunit (GluN1-NTD). ART5803 blocks the internalization of NMDAR induced by pathogenic autoantibodies and restores the expression and function of NMDAR on the cell surface. Moreover, ART5803 reverses behavioral abnormalities and the expression of NMDAR in marmoset disease models. ABT-147 can be utilized in research on anti-NMDAR encephalitis.

ART5803

Copy Product Info
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Catalog No. T9901A-1811

ART5803 is a humanized IgG1 monoclonal antibody inhibitor targeting NMDAR. It binds with high affinity to the N-terminal domain (NTD) of the NMDAR GluN1 subunit (GluN1-NTD). ART5803 blocks the internalization of NMDAR induced by pathogenic autoantibodies and restores the expression and function of NMDAR on the cell surface. Moreover, ART5803 reverses behavioral abnormalities and the expression of NMDAR in marmoset disease models. ABT-147 can be utilized in research on anti-NMDAR encephalitis.

ART5803
Cas No. 3058434-76-4
Pack SizePriceUSA StockGlobal StockQuantity
1 mgInquiryInquiryInquiry
5 mgInquiryInquiryInquiry
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
ART5803 is a humanized IgG1 monoclonal antibody inhibitor targeting NMDAR. It binds with high affinity to the N-terminal domain (NTD) of the NMDAR GluN1 subunit (GluN1-NTD). ART5803 blocks the internalization of NMDAR induced by pathogenic autoantibodies and restores the expression and function of NMDAR on the cell surface. Moreover, ART5803 reverses behavioral abnormalities and the expression of NMDAR in marmoset disease models. ABT-147 can be utilized in research on anti-NMDAR encephalitis.
Chemical Properties
Cas No.3058434-76-4
Storage & Solubility Information
Storagestore at low temperature | store at -20°C | Shipping with blue ice/Shipping at ambient temperature.

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