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    (125)
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    (65)
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    (53)
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Results for "

nos

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    2991
    TargetMol | Inhibitors_Agonists
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    TargetMol | Compound_Libraries
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    24
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    1078
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    628
    TargetMol | Inhibitors_Agonists
NOS-IN-1 
2-Imino-4-methylpiperidine (acetate)
T21700165383-72-2In house
NOS-IN-1 (2-Imino-4-methylpiperidine acetate) is a potent and orally active inhibitor of NO synthase (NOS) isoforms. NOS-IN-1 exhibits IC50s of 0.1 μM, 0.2 μM, and 1.1μM for human iNOS (hiNOS), hnNOS and heNOS, respectively.
  • $59
In Stock
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inos-in-14
3-bromo-1H-indazole-7-carbonitrile
T83625945762-00-5
iNOS-IN-14 (3-bromo-1H-indazole-7-carbonitrile) is a potent nitric oxide synthase (NOS) inhibitor that inhibits the NADPH oxidase activity of nNOS.
  • $29
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Ginsenoside C-K
Ginsenoside K, Ginsenoside compound K
T381139262-14-1
Ginsenoside C-K (Ginsenoside K) is a bacterial metabolite of G-Rb1 exhibiting anti-inflammatory effects by reducing iNOS and COX-2.
  • $30
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Cistanoside A
T5S028593236-42-1
1. Cistanoside A possesses protective activities on CCl4 induced hepatotoxicity in mice, which is involved with increasing free radicals clearing activities, alleviating lipid-overoxidation damage, and improving respiratory chain function in mitochondria.
  • $48
In Stock
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Diphenyleneiodonium chloride
DPI
T71914673-26-1
Diphenyleneiodonium chloride (DPI)(DPI) is an irreversible inhibitor of iNOS and eNOS (IC50 values of 50 nM and 0.3 μM, respectively),and displays broad-spectrum bactericidal activity.
  • $38
In Stock
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TargetMol | Inhibitor Hot
Hydrangenol
TN4234480-47-7In house
Hydrangenol is a natural product and can be isolated from Hydrangea serrata leaves. Hydrangenol is an antiphotoaging compound with oral activity. Hydrangenol can reduce MMP and inflammatory cytokine expression and increase moisturizing factors and antioxidant genes level, result in preventing wrinkle formation.
  • $139
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3-Bromo-7-nitroindazole
T1010774209-34-0
3-Bromo-7-nitroindazole is a specific neuronal nitric oxide synthase (nNOS) inhibitor that affects the synthesis of the intercellular messenger NO throughout the brain and body.
  • $46
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S-Methylisothiourea sulfate
(S)-Methylisothiourea sulfate
T22419867-44-7
S-Methylisothiourea sulfate ((S)-Methylisothiourea sulfate) is a potent and selective inhibitor of iNOS and exerts beneficial effects in rodent models of septic shock[1].
  • $33
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L-NAME hydrochloride
NG-Nitroarginine methyl ester hydrochloride, N(G)-Nitro-L-arginine methyl ester, L-NAME HCl
T657051298-62-5
L-NAME hydrochloride is an inhibitor of nitric oxide synthase (NOS) with an IC₅₀ of 70 μM, and it can be used to induce hypertension and kidney injury models.
  • $30
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Diallyl disulfide
TN15762179-57-9
Diallyl disulfide has antitumor effect, the effect can be enhanced by miR-200b and miR-22.
  • $30
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7-Nitroindazole
T74742942-42-9
7-Nitroindazole is a non-selective inhibitor of NOS isoforms in vitro for neuronal nitric oxide synthase showing a 10-fold selectivity for neuronal NOS.
  • $29
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(Z)-SU4312
T567690828-16-3
(Z)-SU4312 is a inhibitor of MAO-B and NOS(IC50 value of 0.2 μM, 19.0μM,respectively).
  • $56
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L-NMMA acetate
Tilarginine acetate, Methylarginine acetate
T1569753308-83-1
L-NMMA acetate (Tilarginine acetate) is an inhibitor of nitric oxide synthase of all NOS isoforms (i.e. NOS1, NOS2, and NOS3). The Ki values are 0.18, 0.4, and 6 µM for nNOS, eNOS, and iNOS, respectively.
  • $34
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Tetrahydrobiopterin
Sapropterin, BH4, (Rac)-Sapropterin
T1705617528-72-2
Tetrahydrobiopterin (BH4) is a cofactor for aromatic amino acid hydroxylases and an essential cofactor for nitric oxide synthase (NOS), which is used in the study of endothelial dysfunction such as hypertension, hypercholesterolemia, and diabetes.
  • $98
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2-Iminobiotin
Guanidinobiotin
T720613395-35-2
2-Iminobiotin (Guanidinobiotin) is a cyclic guanidino analog of biotin and serves as a reversible inhibitor of inducible nitric oxide synthase (iNOS) and neuronal NOS (nNOS), with Ki values of 21.8 μM for mouse iNOS and 37.5 μM for rat nNOS.
  • $113
35 days
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Tirucallol
TN1006514-46-5
Tirucallol is an antiinflammatory agent isolated from Euphorbia lactea.Tirucallol exerts a topical anti-inflammatory effect in vivo, via a mechanism of action related to the neutrophil migration.
  • $89
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Pelargonidin chloride
TN1058134-04-3
Pelargonidin chloride shows protective effect against CTN-induced oxidative stress in HepG2 cells and up-regulated the activity of detoxification enzyme levels through Keap1/Nrf2 signaling pathway.
  • $81
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Dehydrotrametenolic acid
Dehydroeburicoic acid
TN10866879-05-6
Dehydrotrametenolic acid (Dehydroeburicoic acid) induces necrotic cell death that involves Ca(2+) overload, mitochondrial dysfunction, and calpain activation in human glioblastomas.
  • $450
7-10 days
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26-Deoxyactein
27-Deoxyactein
TN1222264624-38-6
23-epi-26-Deoxyactein (27-Deoxyactein) has anti-inflammatory activity, it inhibits nitric oxide production by reducing iNOS expression without affecting activity of the enzyme. It also has anti-cancer activity, it can inhibit growth of the MCF7 human breast cancer cells and induce cell cycle arrest at G1.
  • $98
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3,4-O-Isopropylidene-shikimic acid
3,4-O-Isopropylidene shikimic acid
TN1238183075-03-8
3,4-O-Isopropylidene-shikimic acid (3,4-O-Isopropylidene shikimic acid) exhibits significant anti-inflammatory, anti-thrombosis, antioxidant, and analgesic effects, and provides protective benefits against trinitrobenzenesulfonic acid-induced experimental colitis in rats, likely because of its antioxidant properties.
  • $68
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α-Humulene
Alpha-caryophyllene
TN13736753-98-6
α-Humulene (Alpha-caryophyllene) is extracted from S.officinalis essential oil.α-Humulene can inhibit tumor cell growth.α-Humulene also shows anti-inflammatory effects, probably by interfering with TNFalpha production and COX-2 and iNOS expression.
  • $30
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Cannabigerol
TN146525654-31-3
Cannabigerol is a high affinity α±2-adrenergic receptor agonist, moderate affinity 5-HT1A receptor antagonist, and low affinity CB1 receptor antagonist ; also binds to the CB2 receptor; it can relieve interocular pressure, which may be of benefit in the treatment of glaucoma.
  • $148
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Cnidicin
TN151614348-21-1
Cnidicin has anti-allergic and anti-inflammatory activity, it inhibits the degranulation of mast cell and the NO generation in RAW 264.7 cells(IC50 value, 7.5 microM). Cnidicin exhibits a significant inhibition on the proliferation of cultured human tumor
  • $153
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Continentalic acid
TN152419889-23-7
Continentalic acid from Aralia continentalis exhibits minimum inhibitory concentrations (MICs) of approximately 8-16 µg/mL against S. aureus, including Methicillin-resistant Staphylococcus aureus (MRSA), Methicillin-susceptible Staphylococcus aureus (MSSA), and standard strains.
  • $35
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