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Lyso-monosialoganglioside GM2 (LysoGM2) ammonium is a lysosomal sphingolipid and an inhibitor of protein kinase C, with an IC50 value of 50 μM. It inhibits the binding of protein kinase C to Phorbol 12,13-dibutyrate. Additionally, LysoGM2 ammonium serves as a specific biomarker for GM2 gangliosidosis and is utilized in the study of sphingolipidosis.
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| 10 mg | Inquiry | Inquiry | Inquiry | |
| 50 mg | Inquiry | Inquiry | Inquiry |
| Description | Lyso-monosialoganglioside GM2 (LysoGM2) ammonium is a lysosomal sphingolipid and an inhibitor of protein kinase C, with an IC50 value of 50 μM. It inhibits the binding of protein kinase C to Phorbol 12,13-dibutyrate. Additionally, LysoGM2 ammonium serves as a specific biomarker for GM2 gangliosidosis and is utilized in the study of sphingolipidosis. |
| Synonyms | LysoGM2 ammonium |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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