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Anti-ADK Antibody (5U907)

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Catalog No. TMAY-02506
Alias AK, adenosine kinase

Anti-ADK Antibody (5U907) is a Rabbit antibody targeting ADK. Anti-ADK Antibody (5U907) can be used in ELISA.

Anti-ADK Antibody (5U907)

Anti-ADK Antibody (5U907)

😃Good
Catalog No. TMAY-02506Alias AK, adenosine kinase
Anti-ADK Antibody (5U907) is a Rabbit antibody targeting ADK. Anti-ADK Antibody (5U907) can be used in ELISA.
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100 μL$270 7-10 days
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Product Introduction

Bioactivity
Description
Anti-ADK Antibody (5U907) is a Rabbit antibody targeting ADK. Anti-ADK Antibody (5U907) can be used in ELISA.
AliasAK, adenosine kinase
Ig Type
Monoclonal Rabbit IgG
Clone
5U907
Reactivity
Human
Application
ELISA
Recommended Dose
ELISA: 1:5000-1:10000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Human ADK (rh ADK; TMPY-04473; AAH03568.1; Met1-His345).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundAdenosine kinase(ADK) belongs to the family of transferases. Adenosine kinase (ADK) is the key enzyme in adenosine metabolism and catalyzes ATP and adenosine into two products: ADP and AMP. Two isoforms of the enzyme adenosine kinase (ADK), which differ at their N-terminal ends, are found in mammalian cells. It has been shown that the two ADK isoforms differ only in their first exons and the promoter regions; hence they arise via differential splicing of their first exons with the other exons common to both isoforms. In adult brain, ADK is primarily present in astrocytes. Several lines of experimental evidence support a critical role of ADK in different types of brain injury associated with astrogliosis, which is also a prominent morphologic feature of temporal lobe epilepsy (TLE). It has been suggested that dysregulation of ADK in astrocytes is a common pathologic hallmark of TLE. Moreover, in vitro data suggest the existence of an additional layer of modulatory crosstalk between the astrocyte-based adenosine cycle and inflammation. ADK also contributes to CK homeostasis in vivo.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Human ADK protein (TMPY-04473)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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