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Isofouquierol is a selective inhibitor that targets nitric oxide (NO) production and exhibits anti-inflammatory properties. It blocks excessive NO production by inhibiting pathways associated with inducible nitric oxide synthase (iNOS). Isofouquierol is applicable for research on inflammation-related diseases, such as chronic inflammation and immune disorders.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 10 mg | Inquiry | Inquiry | Inquiry | |
| 50 mg | Inquiry | Inquiry | Inquiry |
| Description | Isofouquierol is a selective inhibitor that targets nitric oxide (NO) production and exhibits anti-inflammatory properties. It blocks excessive NO production by inhibiting pathways associated with inducible nitric oxide synthase (iNOS). Isofouquierol is applicable for research on inflammation-related diseases, such as chronic inflammation and immune disorders. |
| In vitro | Isofouquierol, at concentrations of 30 μM and 100 μM, exhibits inhibition rates on NO production in LPS-activated mouse peritoneal macrophages of 18.4% and 86.6% respectively. |
| Molecular Weight | 460.74 |
| Formula | C30H52O3 |
| Cas No. | 53822-99-4 |
| Smiles | C[C@]12[C@@]([C@]3(C)[C@@](CC1)(C(C)(C)[C@@H](O)CC3)[H])(CC[C@]4([C@@]2(C)CC[C@@]4([C@@](C/C=C/C(C)(C)O)(C)O)[H])[H])[H] |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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