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Anti-Denosumab Antibody (4H644) is a Mouse antibody targeting Denosumab. Anti-Denosumab Antibody (4H644) can be used in ELISA, Sandwich ELISA, Competitive ELISA.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 40 μg | $305 | 7-10 days | 7-10 days |
| Description | Anti-Denosumab Antibody (4H644) is a Mouse antibody targeting Denosumab. Anti-Denosumab Antibody (4H644) can be used in ELISA, Sandwich ELISA, Competitive ELISA. |
| Synonyms | Prolia Xgeva, Prolia, AMG-162, AMG 162 |
| Ig Type | IgG1, κ |
| Clone | 4H644 |
| Specificity | Denosumab |
| Application | |
| Recommended Dose | ELISA: 0.01-0.1 µg/ml; Sandwich ELISA: Capture with TMAJ-00031 and detected by TMAJ-00029 Capture: 1-5 µg/ml Detection: 0.5-1 μg/ml; Competitive ELISA: 1-5 μg/ml |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Purification | Protein A affinity column |
| Appearance | Lyophilized. Reconstitute the lyophilized powder with deionized water (or equivalent) to a final concentration of 0.5 mg/mL. |
| Formulation | Lyophilized with PBS, pH 7.2, containing 0.02% sodium azide. |
| Research Background | Denosumab with trade name Prolia, is an FDA-approved drug for the treatment of patients with osteoporosis, treatment-induced bone loss, metastases to bone, and giant cell tumor of bone. Denosumab is a fully human monoclonal antibody that works as a RANK ligand (RANKL) inhibitor. Denosumab can bind RANKL, preventing RANKL from activating RANK, its receptor on the osteoclast surface. |
| Conjucates | Unconjugated |
| Immunogen | Denosumab F(ab')2 |
| Stability & Storage | The lyophilized product store at -20°C or -80°C for 12 months. The reconstituted antibody can be stored at 2°C-8°C for 2-3 weeks or at -20°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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