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Curvularin
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Catalog No. T13628Cas No. 10140-70-2
Alias (S)-Curvularin
Curvularin ((S)-Curvularin) is a quorum-sensing antagonist of Pseudomonas aeruginosa RhlR extractable from Curvularia lunata, a mycotoxin with anti-inflammatory activity, inhibition of cytokine-induced NO synthase, and inhibition of lipopolysaccharide-induced inflammation in antimyelocytes. study inflammation.
Curvularin
😃Good
Catalog No. T13628Alias (S)-CurvularinCas No. 10140-70-2
Curvularin ((S)-Curvularin) is a quorum-sensing antagonist of Pseudomonas aeruginosa RhlR extractable from Curvularia lunata, a mycotoxin with anti-inflammatory activity, inhibition of cytokine-induced NO synthase, and inhibition of lipopolysaccharide-induced inflammation in antimyelocytes. study inflammation.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 5 mg | $675 | 35 days | 35 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
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Chemical Properties
| Description | Curvularin ((S)-Curvularin) is a quorum-sensing antagonist of Pseudomonas aeruginosa RhlR extractable from Curvularia lunata, a mycotoxin with anti-inflammatory activity, inhibition of cytokine-induced NO synthase, and inhibition of lipopolysaccharide-induced inflammation in antimyelocytes. study inflammation. |
| Targets&IC50 | iNOS:9.5 µM |
| Synonyms | (S)-Curvularin |
| Molecular Weight | 292.33 |
| Formula | C16H20O5 |
| Cas No. | 10140-70-2 |
| Smiles | C[C@H]1CCCCCC(=O)c2c(O)cc(O)cc2CC(=O)O1 |
| Relative Density. | 1.2g/cm3 |
| Color | White |
| Appearance | Solid |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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