thr

Resmetirom (VIA-3196) is a highly selective thyroid hormone receptor β (THR-β) agonist.

PCO371 (2,4-Imidazolidinedione, 1-(3,5-dimethyl-4-(2-((4-oxo-2-(4-(trifluoromethoxy)phenyl)-1,3,8-triazaspiro(4.5)dec-1-en-8-yl)sulfonyl)ethyl)phenyl)-5,5-dimethyl-) is an orally active full agonist of parathyroid hormone receptor 1. It has no effect on PTH type 2 receptor.

Liothyronine (Tresitope) is an active form of thyroid hormone, binding to β1 thyroid hormone receptor (TRβ1), and activates its activity.

Reverse T3 (3,3',5'-triiodo-L-thyronine) inhibits the increase of sodium current generated by other thyroid hormone analogs in neonatal rat myocytes.

Protirelin (Thyroliberin) is a tripeptide that stimulates the release of thyrotropin and prolactin.

THR-0921 (CLX-0921) is a peroxisome proliferator-activated receptor (PPAR) agonist that can be used to study cardiovascular and metabolic diseases.

Fmoc-Gly-Thr(psi(Me,Me)pro)-OH is a polypeptide composed of glycine and threonine containing a (psi(Me,Me)pro) modification.

(D-Ser2)-Leu-Enkephalin-Thr is a delta selective agent of opioid receptor and shows analgesic effects.

H-Glu-Thr-OH (L-α-Glutamyl-L-threonine) is a dipeptide composed of two amino acids—glutamic acid (Glu) and threonine (Thr)—linked by a peptide bond and functions as an agonist of the extracellular calcium-sensing receptor (CaSR).

Fmoc-Gln(Trt)-Thr(psi(Me,Me)pro)-OH is a dipeptide.

Fmoc-Lys(Boc)-Thr(psi(Me,Me)pro)-OH is a dipeptide.

Fmoc-Glu(OtBu)-Thr(psi(Me,Me)pro)-OH is a dipeptide composed of Fmoc-protected glutamic acid with a tert-butyl ester side chain and threonine modified with a psi(Me,Me)pro residue.

Fmoc-Asp(OtBu)-Thr(psi(Me,Me)pro)-OH is a dipeptide consisting of N-(9-fluorenylmethoxycarbonyl)-L-aspartic acid β-tert-butyl ester and a threonine analogue incorporating a non-native proline mimic with dimethyl substitution at the pseudopeptide bond.

FMOC-L-THR (AZP-531) is an analogue of unacylated ghrelin designed to improve glycaemic control and reduce weight. The O-glycosidic linkage and the O-acetyl protection in this building block is stable to both piperidine and TFA, making it completely compatible with standard protocols in Fmoc solid phase peptide synthesis. The Tn antigen is a tumor-associated carbohydrate antigen that is not normally expressed in peripheral tissues or blood cells. Expression of this antigen, which is found in a majority of human carcinomas of all types, arises from a blockage in the normal O-glycosylation pathway in which glycans are extended from the common precursor GalNAcα1-O-Ser Thr (Tn +antigen)[1].

Fmoc-Thr(GalNAc(Ac)3-β-D)-OH impedes cancer cell proliferation by selectively interacting with complex oncogenic pathways and enhancing the immune response [1].

H-D-Thr(tBu)-OH is a useful organic compound for research in life sciences [Catalog No.: T67086, CAS No.: 201274-81-9].

Fmoc-Tyr(tBu)-Thr(psi(Me,Me)pro)-OH is an essential organic compound for life sciences research, identified by catalog number T66619 and CAS number 920519-31-9.

N-Myristoyl-Lys-Arg-Thr-Leu-Arg is a protein kinase C (PKC) inhibitor (IC50 = 75 μM) that effectively inhibits IL-2 receptor induction and IL-2 production in the human leukemic cell line Jurkat [1].

Fmoc-Allo-Thr(tBu)-OH is a useful organic compound for research related to life sciences. The catalog number is T65177 and the CAS number is 201481-37-0.

Ser-Asn-Thr-Arg is a tetrapeptide compound formed by truncation of a transcription activator-like effector.

Fmoc-Phe-Thr(psi(Me,Me)pro)-OH is an essential organic compound for life sciences research, catalog number T64451, CAS number 1196703-48-6.

Z-Thr-OH is a useful organic compound for research related to life sciences. The catalog number is T67545 and the CAS number is 19728-63-3.

Myristoyl-(Lys12,27,28)-VIP-Gly-Gly-Thr (free acid) acts as a selective and potent antagonist of the VPAC2 receptor [1].

Lys-Arg-Thr-Leu-Arg-Arg (KRTLRR) acetate is a hexapeptide. It serves as a substrate for the EGF receptor protein kinase C and is utilized to assess the activity of protein kinase C.