anti-inflammatory

Dimethyl sulfoxide (DMSO) is a commonly used solvent to dissolve polar and non-polar compounds. Dimethyl sulfoxide has been widely used for masterbatch preparation of compounds in biological experiments. Dimethyl sulfoxide has bacteriostatic activity.

N,N-Dimethylacetamide (DMAc) is a drug excipient with blood-brain barrier permeability and anti-inflammatory activity, acting through inhibition of the NF-κB signaling pathway. N,N-Dimethylacetamide can reduce endotoxin-induced inflammatory responses in vivo.

15-hydroxypentadecanoic acid is a fatty acid found in soybean oil and rapeseed oil that has anti-inflammatory, antibacterial, and antioxidant activities.

(R)-Naproxen acyl-β-D-glucuronide ((R)-Naproxen-β-D-glucuronide) is a metabolite with anti-inflammatory properties. It serves as a sensitive fluorescent substrate for pre-glutamyl peptidase 1, producing a blue reaction upon cleavage.

All-trans-3,4-Didehydro retinoic acid (3,4-DHRA) is an active compound that regulates gene expression by binding to retinoic acid receptors (RAR), subsequently activating them. It plays a crucial role in the development and differentiation of the skin, offering potential anti-tumor and anti-inflammatory properties. Additionally, all-trans-3,4-Didehydro retinoic acid is under investigation for its ability to suppress various diseases, including skin disorders and certain types of cancer.

Geranylacetone(Z E) (Dihydropseudoionone) is a naturally occurring compound found in the essential oils of many plants, including rosemary, lavender and jasmine. It has antioxidant, anti-inflammatory and anti-microbial properties.

13-POHSA (palmitoleic acid esterified to 13-hydroxy stearic acid) is a type of branched fatty acid esters of hydroxy fatty acids (FAHFAs), which have recently been discovered as endogenous lipids whose levels are modulated by fasting and high-fat diets, and are linked to insulin sensitivity in mice. Notably, the concentration of 13-POHSA in the serum significantly increases in glucose tolerant AG4OX mice, a model that overexpresses the Glut4 glucose transporter in adipose tissue, suggesting its physiological relevance. Like other FAHFAs, 13-POHSA is believed to enhance glucose tolerance, promote insulin secretion, and exert anti-inflammatory properties, highlighting its potential importance in managing metabolic syndrome and inflammation.

Carboxymethyl-β-cyclodextrin, 99% is a cationic cyclodextrin that is commonly used as a drug carrier and can bind nonsteroidal anti-inflammatory drugs (NSAIDs) with high efficiency and selectivity.

Spirulina C-phycocyanin is a component of the light-harvesting phycobilisome complex in photosystem II and is a prominently present pigment-protein in Spirulina. Spirulina C-phycocyanin possesses antioxidant, anti-inflammatory, antiplatelet, hepatoprotective, and cholesterol-lowering properties. Spirulina C-phycocyanin can be detected through Raman spectral measurement.

Ethylenediaminetetraacetic acid (EDTA) sodium hydrate is a metal chelator that binds with divalent and trivalent metal cations, including calcium. It exhibits antibacterial, anti-inflammatory, antioxidant, anti-hypercalcemic, and anticoagulant properties. EDTA sodium hydrate reduces protein oxidation damage catalyzed by metal ions and maintains a reducing environment during protein purification, making it a common choice for protein purification and storage. Additionally, it can alleviate liver fibrosis and is used in research related to coronary artery disease and neurological disorders.

Poloxamer 188 is a nonionic linear copolymer known for its surfactant properties. In various tissue damage models, Poloxamer 188 demonstrates antithrombotic, anti-inflammatory, and cytoprotective activities.

Dextran sulfate sodium salt (MW 9000-20000) (DSS (MW 9000-20000)) is a negatively charged sulfated polysaccharide. It exhibits antiviral, antibacterial, anti-inflammatory, antifibrotic, and wound healing properties. Dextran sulfate sodium salt can be used as an additive in cell culture media to prevent cell aggregation and also serves as a gel-forming agent in cosmetics.

Dextran sulfate, low sulfate (MW 5000), is a natural biopolymer and a sulfated polysaccharide. It exhibits antiviral, antibacterial, anti-inflammatory, antifibrotic, and wound healing properties. Additionally, dextran sulfate serves as an additive in cell culture media to prevent cell aggregation and functions as a gel-forming agent in cosmetics.

Dextran sulfate, low sulfate (MW 40000) is a sulfated polysaccharide biopolymer. It exhibits antiviral, antibacterial, anti-inflammatory, antifibrotic, and wound healing properties. Additionally, dextran sulfate can be employed as an additive in cell culture media to prevent cell clumping and as a gelling agent in cosmetic formulations.

Dextran sulfate, high sulfate (MW 5000), is a sulfated polysaccharide that functions as a biopolymer. It exhibits antiviral, antibacterial, anti-inflammatory, antifibrotic, and wound-healing properties. Additionally, dextran sulfate can be utilized as an additive in cell culture media to prevent cell aggregation and serves as a gelling agent in cosmetics.

Dextran sulfate sodium salt (MW 6500-10000) (DSS (MW 6500-10000)) is a negatively charged sulfated polysaccharide. It possesses antiviral, antibacterial, anti-inflammatory, antifibrotic, and wound-healing properties. Additionally, it can be used as an additive in cell culture media to prevent cell aggregation and as a gel-forming agent in cosmetics.

Biliverdin dihydrochloride is a tetrapyrrolic pigment resulting from the degradation of heme. Heme is broken down by heme oxygenase into biliverdin, carbon monoxide, and iron. Subsequently, biliverdin is rapidly converted to bilirubin by biliverdin reductase. Biliverdin dihydrochloride exhibits antimutagenic, antioxidant, anti-inflammatory, and immunosuppressive properties.

6-Methoxyquinoline is composed of a quinoline ring system with a methoxy group attached to the sixth carbon atom. This compound is naturally found in certain plants such as tobacco and tea. It has demonstrated bioactive properties, including antioxidant, anti-inflammatory, and antitumor effects. In addition, 6-Methoxyquinoline serves as a foundational material for synthesizing other organic compounds, particularly those with potential pharmaceutical applications. Due to its ability to bind with nucleic acids and proteins, it is also used as a fluorescent probe in biochemical and biomedical research.

Linoleate sodium is an orally active regulator of IL8 mediated by JNK and NF-κB pathways. It can alter the composition of fatty acids and the production of metabolites within cells. Additionally, Linoleate sodium exhibits anti-inflammatory, immunomodulatory properties and influences tumor cell growth.

Isothiazole-5-carboxylic acid (8-Isoquinoline-methaneaminedihydrochloride) is an organic compound known for its antibacterial, anticancer, and anti-inflammatory properties. It holds promise in the development of novel compounds to combat various diseases. This compound exhibits a wide range of potential pharmacological activities, aiding in the enhancement of existing inhibitory strategies.

Cerium oxide, 99.99% metals basis, <5 μm, functions as a biochemical analysis reagent with anti-inflammatory properties and mimics the activity of SOD and catalase. It is applicable in treating chronic inflammation and is utilized in industrial applications such as solid oxide fuel cells, solar cells, catalysts, oxygen pumps, and gas sensors.

CLA, or conjugated linoleic acid, is a polyunsaturated fatty acid that naturally occurs in various animal products such as meat and dairy. It offers several potential health benefits for humans, including the reduction of body fat, improved insulin sensitivity, and anti-inflammatory effects. Extensively researched for its impact on weight loss and muscle growth, CLA also shows potential in preventing chronic diseases like heart disease and cancer. Additionally, it is available as a dietary supplement in capsule form.

Chitoheptaose is an oligosaccharide derived from the exoskeletons of crustaceans such as crabs, shrimp, and lobsters. It exhibits antioxidant, anti-inflammatory, and anti-apoptotic properties, making it useful for cardiac studies, particularly myocarditis research. Chitoheptaose offers cardioprotective benefits, enhancing cardiac parameters [left ventricular internal diameter, end-systolic and end-diastolic dimensions, ejection fraction, and fractional shortening], and modulating inflammatory cytokines (IL-1β).

CORM-A1 (Sodium boranocarbonate) is a water-soluble carbon monoxide (CO) releasing molecule that facilitates the study of CO's effects on cellular systems. As CO is produced by the degradation of heme by heme oxygenase, it serves as a crucial gaseous signaling mediator in mammalian cells. CORM-A1 not only possesses antioxidant and anti-inflammatory properties but also modulates CO release in a pH and temperature-dependent manner, promoting mild vasodilation and hypotension. Additionally, CORM-A1 has been shown to provide cellular protection in primary cultures of astrocytes under oxidative stress, enhancing autophagy due to its boron content.