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Otilimab (Synonyms: MOR103, GSK 3196165)

Catalog No. T77125 Copy Product Info
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Otilimab (GSK 3196165) is a humanized monoclonal antibody against granulocyt-macrophage colony-stimulating factor (GM-CSF). Otilimab has anti-inflammatory activity, regulates the biological function of GM-CSF by blocking the interaction between GM-CSF and its cell surface receptors, and can be used in studies to treat severe COVID-19 pneumonia.

Otilimab

Copy Product Info
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Catalog No. T77125
Synonyms MOR103, GSK 3196165

Otilimab (GSK 3196165) is a humanized monoclonal antibody against granulocyt-macrophage colony-stimulating factor (GM-CSF). Otilimab has anti-inflammatory activity, regulates the biological function of GM-CSF by blocking the interaction between GM-CSF and its cell surface receptors, and can be used in studies to treat severe COVID-19 pneumonia.

Otilimab
Cas No. 1638332-55-4
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Pack SizePriceUSA StockGlobal StockQuantity
1 mg$122-In Stock
5 mg$322-In Stock
10 mg$549-In Stock
25 mg$873-In Stock
50 mg$1,170-In Stock
100 mg$1,580-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:> 95%
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Otilimab (GSK 3196165) is a humanized monoclonal antibody against granulocyt-macrophage colony-stimulating factor (GM-CSF). Otilimab has anti-inflammatory activity, regulates the biological function of GM-CSF by blocking the interaction between GM-CSF and its cell surface receptors, and can be used in studies to treat severe COVID-19 pneumonia.
SynonymsMOR103, GSK 3196165
Reactivity
Human
Verified Activity
Immobilized Human GM-CSF Protein (aa 18-144, His) at 2 μg/mL (30 μL/well) can bind Otilimab. The EC50 is 10.54 ng/mL.
verifiedActivity
Application
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Gene ID
Uniprot ID
TargetCSF2/GM-CSF
Chemical Properties
Molecular Weight142.22 kDa
Cas No.1638332-55-4
Antibody Information
IsotypeHuman IgG1 lambda2
Recommended Isotype Control
Storage & Solubility Information
Storagestore at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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