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Otilimab (Synonyms: MOR103, GSK 3196165)
Catalog No. T77125 Copy Product Info
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Otilimab (GSK 3196165) is a humanized monoclonal antibody against granulocyt-macrophage colony-stimulating factor (GM-CSF). Otilimab has anti-inflammatory activity, regulates the biological function of GM-CSF by blocking the interaction between GM-CSF and its cell surface receptors, and can be used in studies to treat severe COVID-19 pneumonia.
Otilimab
Copy Product Info🥰Excellent
Catalog No. T77125
Synonyms MOR103, GSK 3196165
Otilimab (GSK 3196165) is a humanized monoclonal antibody against granulocyt-macrophage colony-stimulating factor (GM-CSF). Otilimab has anti-inflammatory activity, regulates the biological function of GM-CSF by blocking the interaction between GM-CSF and its cell surface receptors, and can be used in studies to treat severe COVID-19 pneumonia.
Otilimab
Cas No. 1638332-55-4
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $122 | - | In Stock | |
| 5 mg | $322 | - | In Stock | |
| 10 mg | $549 | - | In Stock | |
| 25 mg | $873 | - | In Stock | |
| 50 mg | $1,170 | - | In Stock | |
| 100 mg | $1,580 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.
For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:> 95%
Appearance:Liquid
Color:Transparent
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Product Introduction
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| Description | Otilimab (GSK 3196165) is a humanized monoclonal antibody against granulocyt-macrophage colony-stimulating factor (GM-CSF). Otilimab has anti-inflammatory activity, regulates the biological function of GM-CSF by blocking the interaction between GM-CSF and its cell surface receptors, and can be used in studies to treat severe COVID-19 pneumonia. |
| Synonyms | MOR103, GSK 3196165 |
| Reactivity | Human |
| Verified Activity | Immobilized Human GM-CSF Protein (aa 18-144, His) at 2 μg/mL (30 μL/well) can bind Otilimab. The EC50 is 10.54 ng/mL.  |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | CSF2/GM-CSF |
| Molecular Weight | 142.22 kDa |
| Cas No. | 1638332-55-4 |
| Isotype | Human IgG1 lambda2 |
| Recommended Isotype Control |
| Storage | -20°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
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