Shopping Cart

Remove All
Your shopping cart is currently empty

antcin A

Name: antcin A
Brand: TargetMol
SKU: TN7099
Price: 316 USD
Availability: InStock
Rating: 5 (10 reviews)

😃Good

Catalog No. TN7099Cas No. 163597-24-8

antcin A is a steroid-like phytochemical isolated from the fruiting bodies of a precious edible mushroom Antrodia cinnamomea with strong anti-inflammatory and anti-tumor effects.

antcin A

😃Good

Purity: 96.43%

Catalog No. TN7099Cas No. 163597-24-8

antcin A is a steroid-like phytochemical isolated from the fruiting bodies of a precious edible mushroom Antrodia cinnamomea with strong anti-inflammatory and anti-tumor effects.

Pack Size	Price	Availability
1 mg	$316	In Stock
5 mg	$854	In Stock
10 mg	$1,210	In Stock
25 mg	$2,337	In Stock
50 mg	$3,670	Inquiry
1 mL x 10 mM (in DMSO)	$1,037	In Stock

Add to Cart

Add to Quotation

Bulk & Custom

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

Select Batch

Purity:96.43%

Resource Download

COA

Product Introduction

Bioactivity

Description	antcin A is a steroid-like phytochemical isolated from the fruiting bodies of a precious edible mushroom Antrodia cinnamomea with strong anti-inflammatory and anti-tumor effects.
In vitro	Antcin A could significantly inhibit the occurrence of pyrolysis, decrease the expression of inflammatory factors, inhibit the activation and assembly of NLRP3 inflammasome, and significantly down-regulate the expression of NLRP3, Caspase-1 and GSDMD-NT in KCs[1].
In vivo	In NAFLD mice, Antcin A could suppress the inflammatory response in liver tissues of mice, reduce lipid deposition, down-regulate the levels of ALT and AST, and improve liver function in mice. Antcin A could also inhibit the activation of NLRP3 inflammasome in liver tissue and decrease the level of inflammatory factors[1].

Chemical Properties

Molecular Weight	454.64
Formula	C₂₉H₄₂O₄
Cas No.	163597-24-8
Smiles	C[C@@]12C3=C([C@]4([C@](C)(CC3=O)[C@@]([C@@H](CCC(C(C(O)=O)C)=C)C)(CC4)[H])[H])CC[C@]1([C@H](C)C(=O)CC2)[H]
Relative Density.	1.11 g/cm3 (Predicted)
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (109.98 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.1995 mL	10.9977 mL	21.9954 mL	109.9771 mL
5 mM	0.4399 mL	2.1995 mL	4.3991 mL	21.9954 mL
10 mM	0.2200 mL	1.0998 mL	2.1995 mL	10.9977 mL
20 mM	0.1100 mL	0.5499 mL	1.0998 mL	5.4989 mL
50 mM	0.0440 mL	0.2200 mL	0.4399 mL	2.1995 mL
100 mM	0.0220 mL	0.1100 mL	0.2200 mL	1.0998 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc