virus

PF-07321332 is a potent and orally active inhibitor of SARS-CoV 3C-like protease (3CLPRO) .

U0126-EtOH (U0126 Ethanol) is a non-ATP competitive specific inhibitor of MEK1 2 (IC50: 0.07 0.06 μM).

Catalpol (Catalpinoside) is an iridoid glycoside with neuroprotective, anti-inflammatory, and anti-hepatitis virus effects.

3,29-O-Dibenzoyloxykarounidiol is a natural product with regulate blood sugar level, has potent inhibitory effects on Epstein-Barr virus early antigen (EBV-EA) induced by tumor promoter 12-O-tetradecanoylphorbol-13-acetate (TPA).

(-)-Arctigenin ((-)-Arctigenin) is found in burdock. (-)-Arctigenin is isolated from Cnicus benedictus, Forsythia viridissima, Arctium lappa, Ipomoea cairica and others (CCD). Arctigenin is a lignan found in certain plants of the Asteraceae, including the Greater burdock (Arctium lappa) and Saussurea heteromalla. It has shown antiviral and anticancer effects. It is the aglycone of arctiin.

AG-1478 (NSC-693255) (Tyrphostin AG-1478) is a selective EGFR inhibitor.

GS-441524 treatment of cats with naturally occurring feline infectious peritonitis.

Fusion glycoprotein (92-106) [Human respiratory syncytial virus] is a peptide with the sequence H2N-Glu-Leu-Gln-Leu-Leu-Met-Gln-Ser-Thr-Pro-Pro-Thr-Asn-Asn-Arg-OH, MW= 1741.96.

Rabies Virus Glycoprotein (TFA), a 29-amino acid-derived cell-penetrating peptide from the Rabies Virus Glycoprotein, can cross the blood-brain barrier (BBB) and enter brain cells.

CEF19, Epstein-Barr Virus latent NA-3A (458-466), is a peptide epitope, YPLHEQHGM, representing residues 458-466 of the type 1 Epstein-Barr Virus (EBV) nuclear antigen 3A protein (B95.8 strain).

Influenza A virus-IN-8 (S5), a macrocyclic peptide, exhibits no cytotoxicity and acts as a potent inhibitor of Influenza A Virus (IAV), demonstrating significant protease stability, with IC50 values of 6.7 nM for H1 and 6.6 nM for H5 variants. It has a high affinity for H1 variants, binding to a conserved region in the HA stem with a dissociation constant (Kd) of 1.0 nM [1].

Moloney murine leukemia virus reverse transcriptase (MMLV RT) is a monomeric replicative polymerase intrinsic to the retrovirus life cycle [1].

Hepatitis B Virus Pre-S Region (120-145) is a preS2 peptide that effectively blocks the attachment of single-chain Fv fragment (scFv) or IgG to recombinant Hepatitis B surface antigen (r-HBsAg) [1].

Rabies Virus Glycoprotein acetate is a useful organic compound for research related to life sciences and the catalog number is TP1871L.

Influenza virus-IN-3 (compound 9) is a potent inhibitor of selective influenza viruses, with IC50 values of 0.88 μM for H5N1, 0.10 μM for H5N2, 5.5 μM for H5N6, and 0.51 μM for H5N8. Influenza virus-IN-3 exhibits antiviral and NA (neuraminidase) inhibitory effects with low cytotoxicity (CC50 > 200 μM).

Influenza virus-IN-7 (Example 16) is an orally active cap-dependent endonuclease inhibitor used in influenza viral infectious disease research [1].

The Anti-West Nile dengue virus E protein Antibody (E60) is a mouse-derived IgG2akappa antibody targeting the West Nile dengue virus E protein. Its isotype control is MouseIgG2akappa, Isotype Control.

Anti-virus agent 1 (compound 4i), a phosphoramidate prodrug of GS-5734, exhibits potent antiviral efficacy and is primarily utilized in coronavirus and Ebola virus (EBOV) research.

The hepatitis B virus (HBV) core protein has been found in the nucleus, the cytoplasm, or both of HBV-infected hepatocytes. nuclear localization of the HBV core protein is negatively regulated by phosphorylation during the cell cycle.

HLA-A*0301-restricted epitope from Epstein-Barr Virus , EBV BRLF-1 (148-156).

Rabies Virus Glycoprotein is a 29 amino acid fragment generated from rabies virus glycoprotein (RVG). This peptide specifically binds to the acetylcholine receptor expressed by neuronal cells.

Influenza A virus fragment has the RNA sequence of Leu-Lys-Phe-Ala-Phe-Ser-Met-Met.

CEF8, Influenza Virus NP (383-391), is an influenza A virus nucleoprotein containing residues 383 to 391, and it is the most important HLA-B*2705-restricted epitope in the nucleoprotein of influenza A viruses, associated with escape from cytotoxic T lymphocytes-mediated immunity. [HLA-B*3501 restricted influenza virus nucleoprotein epitope (383-391).]

Influenza virus-IN-8 (compound A4), an inhibitor of the influenza virus (Influenza Virus), functions by inducing aggregation of the viral nucleoprotein (NP) and blocking its accumulation in the nucleus. This compound exhibits broad-spectrum anti-influenza properties, effectively inhibiting the replication and transcription of influenza A virus. Additionally, Influenza virus-IN-8 is effective against Oseltamivir-resistant H1N1 pdm09 strains [1].