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Anti-Influenza A Virus Hemagglutinin/HA Antibody (4B311) is a Rabbit antibody targeting Influenza A Virus Hemagglutinin/HA. Anti-Influenza A Virus Hemagglutinin/HA Antibody (4B311) can be used in ELISA,WB.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
20 μL | $92 | 7-10 days | |
100 μL | $292 | 7-10 days |
Description | Anti-Influenza A Virus Hemagglutinin/HA Antibody (4B311) is a Rabbit antibody targeting Influenza A Virus Hemagglutinin/HA. Anti-Influenza A Virus Hemagglutinin/HA Antibody (4B311) can be used in ELISA,WB. |
Ig Type | Rabbit IgG |
Clone | 4B311 |
Specificity | H1N1 (A/California/04/2009) HA H1N1 (A/California/07/2009) HA Has cross-reactivity in ELISA and WB with H1N1 (A/Brisbane/02/2018) HA H1N1 (A/California/04/2009) HA Protein H1N1 (A/California/04/2009) HA trimer Protein H1N1 (A/California/07/2009) HA Protein H1N1 (A/Guangdong-Maonan/SWL1536/2019) / (A/Hawaii/70/2019) HA H1N1 (A/Michigan/45/2015) HA Protein H1N1 (A/Puerto Rico/8/1934) HA Protein H1N1 (A/Texas/05/2009) HA Protein H1N1 (A/Texas/36/1991) HA Protein H1N1 (A/Texas/36/1991) HA Protein H1N1 (A/Wisconsin/588/2019) / (A/Victoria/2570/2019) HA H1N1 (A/Wisconsin/67/2022) HA Protein H1N1 (A/Victoria/4897/2022) HA Protein H3N2 (A/Brisbane/10/2007) HA Protein H3N2 (A/Cambodia/e0826360/2020) HA H3N2 (A/Darwin/6/2021) HA Protein H3N2 (A/Darwin/6/2021) HA Protein H3N2 (A/Darwin/9/2021) HA Protein H3N2 (A/Darwin/9/2021) HA Protein H3N2 (A/Hong Kong/1/1968) HA Protein H3N2 (A/Hong Kong/2671/2019) HA H3N2 (A/Hong Kong/45/2019) HA H3N2 (A/Hong Kong/4801/2014) HA H3N2 (A/Kansas/14/2017) HA H3N2 (A/Singapore/INFIMH-16-0019/2016) HA H3N2 (A/Switzerland/9715293/2013) HA H3N2 (A/Texas/50/2012) HA Protein Has cross-reactivity in ELISA with H1N1 (A/Beijing/22808/2009) HA H1N1 (A/Brevig Mission/1/1918) HA H1N1 (A/Brisbane/59/2007) HA H1N1 (A/England/195/2009) HA H1N1 (A/New Caledonia/20/1999) HA H1N1 (A/New York/18/2009) HA H1N1 (A/Ohio/07/2009) HA H1N1 (A/Ohio/UR06-0091/2007) HA H1N1 (A/Solomon Islands/3/2006) HA H1N1 (A/Texas/05/2009) HA H1N1 (A/Wisconsin/588/2019) / (A/Victoria/2570/2019) HA Protein H1N1 (A/WSN/1933) HA H1N2 (A/swine/Guangxi/13/2006) HA H1N3 (A/duck/NZL/160/1976) HA H2N2 (A/Canada/720/2005) HA H2N2 (A/Japan/305/1957) HA H3N2 (A/Aichi/2/1968) HA H3N2 (A/Hong Kong/4801/2014) HA Protein H3N2 (A/Perth/16/2009) HA H3N2 (A/Wisconsin/67/X-161/2005) HA H3N2 (A/Wyoming/03/2003) HA H4N4 (A/mallard duck/Alberta/299/1977) HA H4N6 (A/mallard/Ohio/657/2002) HA H4N6 (A/Swine/Ontario/01911-1/99) HA H4N8 (A/chicken/Alabama/1/1975) HA H5N1 (A/Anhui/1/2005) HA H5N1 (A/Anhui/1/2005) HA2 Sub-unit H5N1 (A/bar-headed goose/Qinghai/14/2008) HA H5N1 (A/barnswallow/HongKong/D10-1161/2010) HA1 Subunit H5N1 (A/Cambodia/R0405050/2007) HA H5N1 (A/Cambodia/S1211394/2008) HA H5N1 (A/chicken/India/NIV33487/2006) HA H5N1 (A/Common magpie/Hong Kong/2256/2006) HA H5N1 (A/duck/Hunan/795/2002) HA H5N1 (A/Egypt/2321-NAMRU3/2007) HA H5N1 (A/Egypt/N05056/2009) HA H5N1 (A/goose/Guiyang/337/2006) HA H5N1 (A/Hong kong/213/03) HA H5N1 (A/Hong Kong/483/97) HA H5N1 (A/Hubei/2011) HA H5N1 (A/Indonesia/5/2005) HA Protein H5N1 (A/Japanese white-eye/Hong Kong/1038/2006) HA H5N1 (A/turkey/Turkey/1/2005) HA H5N1 (A/Viet Nam/1203/2004) HA H5N1 (A/Vietnam/1194/2004) HA H5N1 (A/whooper swan/Mongolia/244/2005) HA H5N1 (A/Xinjiang/1/2006) HA H5N2 (A/American green-winged teal/California/HKWF609/07) HA H5N3 (A/duck/Hokkaido/167/2007) HA H5N8 (A/duck/NY/191255-59/2002) HA H6N1 (A/northern shoveler/California/HKWF115/2007) HA H6N4 (A/chicken/HongKong/17/77) HA H7N7 (A/chicken/Netherlands/1/03) HA H7N7 (A/Netherlands/219/03) HA H7N8 (A/mallard/Netherlands/33/2006) HA H7N9 (A/Anhui/1/2013) HA H7N9 (A/Hangzhou/1/2013) HA H7N9 (A/Hangzhou/3/2013) HA H7N9 (A/Pigeon/Shanghai/S1069/2013) HA H7N9 (A/Shanghai/1/2013) HA H7N9 (A/Shanghai/2/2013) HA H7N9 (A/Shanghai/4664T/2013) HA H7N9 (A/Zhejiang/1/2013) HA H8N4 (A/pintail duck/Alberta/114/1979) HA H9N2 (A/Chicken/Hong Kong/G9/97) HA H9N2 (A/Guinea fowl/Hong Kong/WF10/99) HA H9N2 (A/Hong Kong/1073/99) HA H9N2 (A/Hong Kong/35820/2009) HA H10N3 (A/duck/Hong Kong/786/1979) HA H10N3 (A/mallard/Minnesota/Sg-00194/2007) HA H10N9 (A/duck/HongKong/562/1979) HA H11N2 (A/duck/Yangzhou/906/2002) HA H11N9 (A/mallard/Alberta/294/1977) HA H12N1 (A/mallard duck/Alberta/342/1983) HA H12N5 (A/green-winged teal/ALB/199/1991) HA H13N8 (A/black-headed gull/Netherlands/1/00) HA H15N8 (A/duck/AUS/341/1983) HA H16N3 (A/black-headed gull/Sweden/5/99) HA Has cross-reactivity in WB with H1N1 (A/Wisconsin/67/2022) HA Trimer Protein H1N1 (A/Victoria/4897/2022) HA Trimer Protein H5N1 (A/Indonesia/5/2005) HA Protein No cross-reactivity in ELISA and WB with H1N1 (A/Texas/05/2009) HA1 Subunit Protein H1N1 (A/Texas/36/1991) HA1 Subunit Protein H3N2 (A/Texas/50/2012) HA1 Subunit Protein H3N2 (A/Texas/1/1977) HA1 Protein Influenza B (B/Austria/1359417/2021)(Victoria lineage) HA Protein Influenza B (B/Austria/1359417/2021)(Victoria lineage) HA Protein Influenza B (B/Brisbane/60/2008) HA Protein Influenza B (B/Colorado/06/2017) HA Protein Influenza B (B/Florida/4/2006) HA Protein Influenza B (B/PHUKET/3073/2013) HA Protein Influenza B (B/Washington/02/2019) HA Protein No cross-reactivity in ELISA with H1N1 (A/Brevig Mission/1/1918) HA H1N1 (A/California/04/2009) HA1 Sub-unit |
Verified Activity | 1. Anti-HA rabbit monoclonal antibody at 1:5000 dilution. -Sample: Recombinant Protein 10 ng -Lane 1: H1N1 (A/Brisbane/02/2018) HA -Lane 2: H1N1 (A/California/04/2009) HA -Lane 3: H1N1 (A/California/07/2009) HA -Lane 4: H1N1 (A/Guangdong-Maonan/SWL1536/2019) HA -Lane 5: H1N1 (A/Michigan/45/2015) HA -Lane 6: H1N1 (A/Puerto Rico/8/1934) HA -Lane 7: H1N1 (A/Victoria/4897/2022) HA Protein -Lane 8: H1N1 (A/Victoria/4897/2022) HA Trimer Protein -Lane 9: H1N1 (A/Wisconsin/588/2019) / (A/Victoria/2570/2019) HA -Lane 10: H1N1 (A/Wisconsin/67/2022) HA Protein -Lane 11: H1N1 (A/Wisconsin/67/2022) HA Trimer Protein -Lane 12: H3N2 (A/Brisbane/10/2007) HA -Lane 13: H3N2 (A/Cambodia/e0826360/2020) HA -Lane 14: H3N2 (A/Darwin/6/2021) HA Protein -Lane 15: H3N2 (A/Hong Kong/1/1968) HA Protein -Lane 16: H3N2 (A/Hong Kong/2671/2019) HA -Lane 17: H3N2 (A/Hong Kong/45/2019) HA -Lane 18: H3N2 (A/Hong Kong/4801/2014) HA -Lane 19: H3N2 (A/Kansas/14/2017) HA -Lane 20: H3N2 (A/Singapore/INFIMH-16-0019/2016) HA -Lane 21: H3N2 (A/Switzerland/9715293/2013) HA -Lane 22: H5N1 (A/Indonesia/5/2005) HA Protein -Lane 23: Influenza B (B/Brisbane/60/2008) HA -Lane 24: Influenza B (B/Colorado/06/2017) HA -Lane 25: Influenza B (B/Florida/4/2006) HA -Lane 26: Influenza B (B/PHUKET/3073/2013) HA -Lane 27: Influenza B (B/Washington/02/2019) HA -Secondary -Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. -Developed using the ECL technique. -Performed under reducing conditions. 2. Anti-HA rabbit monoclonal antibody at 1:1000 dilution. -Sample: Recombinant Protein 10 ng -Lane A: H3N2 (A/Darwin/9/2021) HA Protein -Lane B: H3N2 (A/Darwin/9/2021) HA Protein -Lane C: H3N2 (A/Darwin/6/2021) HA Protein -Lane D: Influenza B (B/Austria/1359417/2021)(Victoria lineage) HA Protein -Lane E: Influenza B (B/Austria/1359417/2021)(Victoria lineage) HA Protein -Secondary -Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution -Developed using the ECL technique. -Performed under reducing conditions. 3. Anti-Influenza A Virus Hemagglutinin / HA rabbit monoclonal antibody in 1μg/mL. -Sample: Recombinant Protein 10 ng -Lane 1: Influenza A H1N1 (A/Texas/05/2009) Hemagglutinin / HA Protein -Lane 2: Influenza A H1N1 (A/Texas/05/2009) Hemagglutinin Protein (HA1 Subunit) -Lane 3: Influenza A H1N1 (A/Texas/36/1991) Hemagglutinin / HA Protein -Lane 4: Influenza A H1N1 (A/Texas/36/1991) Hemagglutinin Protein (HA1 Subunit) -Lane 5: Influenza A H3N2 (A/Texas/50/2012) Hemagglutinin / HA Protein -Lane 6: Influenza A H3N2 (A/Texas/50/2012) Hemagglutinin Protein (HA1 Subunit) -Lane 7: Influenza A H3N2 (A/Texas/1/1977) Hemagglutinin / HA1 Protein -Lane 8: Influenza A H1N1 (A/Texas/36/1991) Hemagglutinin / HA Protein -Lane 9: Influenza A H5N1 (A/dairy cow/Texas/24-008749-002) Hemagglutinin / HA Protein -Lane 10: Influenza A H1N1 (A/California/04/2009) Hemagglutinin / HA trimer Protein -Secondary -Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution -Developed using the ECL technique. -Performed under reducing conditions. |
Application | |
Recommended Dose | WB: 1:2000-1:20000; ELISA: 1:1000-1:2000 |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Influenza A virus H1N1 Hemagglutinin extracellular domain. |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | The influenza viral Hemagglutinin (HA) protein is a homotrimer with a receptor binding pocket on the globular head of each monomer.HA has at least 18 different antigens. These subtypes are named H1 through H18.HA has two functions. Firstly, it allows the recognition of target vertebrate cells, accomplished through the binding to these cells' sialic acid-containing receptors. Secondly, once bound it facilitates the entry of the viral genome into the target cells by causing the fusion of the host endosomal membrane with the viral membrane. The influenza virus Hemagglutinin (HA) protein is translated in cells as a single protein, HA, or hemagglutinin precursor protein. For viral activation, hemagglutinin precursor protein (HA) must be cleaved by a trypsin-like serine endoprotease at a specific site, normally coded for by a single basic amino acid (usually arginine) between the HA1 and HA2 domains of the protein. After cleavage, the two disulfide-bonded protein domains produce the mature form of the protein subunits as a prerequisite for the conformational change necessary for fusion and hence viral infectivity. |
Conjucates | Unconjugated |
Immunogen | Recombinant Protein: H1N1 HA protein |
Antigen Species | Influenza |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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