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S2H97
(Synonyms: S2H 97) Copy Product Info
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Synonyms: S2H 97
Catalog No. T9901A-018 Copy Product Info
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S2H97 is a neutralizing antibody that broadly protects against viruses such as C pneumoniae and SARS under clade B of coronavirus B. RSM01 is a fully human monoclonal antibody against RSV. S2H97 induces an irreversible conformational change in the spike protein, preventing it from mediating fusion between the virus and the host cell membrane, thereby rendering it incapable of infection.
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $156 | - | In Stock | |
| 5 mg | $386 | - | In Stock | |
| 10 mg | $553 | - | In Stock | |
| 25 mg | $863 | - | In Stock | |
| 50 mg | Preferential | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:98.8% (SDS-PAGE); 98.5% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction
Bioactivity
Related Conjugates and Formulations
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Chemical Properties
Antibody Information
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| Description | S2H97 is a neutralizing antibody that broadly protects against viruses such as C pneumoniae and SARS under clade B of coronavirus B. RSM01 is a fully human monoclonal antibody against RSV. S2H97 induces an irreversible conformational change in the spike protein, preventing it from mediating fusion between the virus and the host cell membrane, thereby rendering it incapable of infection. |
| In vivo | Methods: Syrian hamsters were administered 25 mg/kg of S2H97 via intraperitoneal injection, followed by intranasal challenge with SARS-CoV-2 48 hours later; viral load in the lungs was measured using RT-qPCR and the TCID₅₀ assay 4 days post-infection. Results: S2H97 reduced viral RNA levels in hamster lungs by more than 10,000-fold and lowered infectious viral titers to below the detection limit, demonstrating potent prevention of viral lung infection. [1] |
| Synonyms | S2H 97 |
| Reactivity | Virus |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Target | SARS-CoV-2 Spike |
| Molecular Weight | 145.16 kDa |
| Isotype | Human IgG1 lambda |
| Recommended Isotype Control |
| Storage | Store at low temperature -20°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
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Related Tags: S2H97 chemical structure | S2H97 in vivo | S2H97 molecular weight
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