T38936 |
KRAS G13D peptide, 25 mer
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|
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KRAS G13D peptide, a 25-mer sequence, is derived from the KRAS activating oncogene mutation and serves as an immune pote... |
T72574 |
Axl/Mer/CSF1R-IN-1
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Axl/Mer-IN-1 is an Axl/Mer receptor tyrosine kinase ( Axl/Mer RTK ) and CSF1R inhibitor with K d s of <0.1 μM . |
T26296 |
Triparanol
|
NSC-65345,NSC 65345,NSC65345,MER-29 |
Apoptosis
,
Hedgehog/Smoothened
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Triparanol interferes with posttranslational modification of Hedgehog signaling molecules as well as the sterol sensing ... |
T0318 |
Azacyclonol
|
MER 17,γ-pipradol,MDL 4829,Ataractan |
5-HT Receptor
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Azacyclonol is a drug used to diminish hallucinations in psychotic individuals. |
T13074 |
TAM-IN-2
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TAM Receptor
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TAM-IN-2 is an inhibitor of TAM. |
T1968 |
UNC2250
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TAM Receptor
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UNC2250 is an effective and specific Mer inhibitor (IC50=1.7 nM). |
T2311 |
LDC1267
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TAM Receptor
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LDC1267 is a excellently specific TAM(Tyro3, Axl and Mer) kinase inhibitor, for Mer( IC50<5 nM), Tyro3(IC50=8 nM), and A... |
T17205 |
UNC2541
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Others
,
FLT
,
TAM Receptor
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UNC2541 is a potent and Mer tyrosine kinase (MerTK)-specific inhibitor. It also binds in the MerTK ATP pocket (IC50: 4.4... |
T6982 |
SGI-7079
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Src
,
c-RET
,
c-Met/HGFR
,
FLT
,
TAM Receptor
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SGI-7079 is a new selective Axl inhibitor. SGI-7079 can be a dose-dependent manner inhibited growth of tumors. It is als... |
T2005 |
Dubermatinib
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TP0903 |
TAM Receptor
,
Apoptosis
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|
TP-0903 is a potent and selective Axl kinase inhibitor. |
T6907 |
NPS-1034
|
NPS 1034,NPS1034 |
Apoptosis
,
TAM Receptor
,
c-Met/HGFR
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NPS-1034 is a dual Met/Axl inhibitor with IC50 of 48 nM and 10.3 nM, respectively. |
T70265 |
AL-6556
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AL-6556 is a prostaglandin DP receptor agonist. |
T6269 |
Bemcentinib
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BGB324,R428 |
TAM Receptor
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R428 is a selective inhibitor of Axl (IC50: 14 nM) and has been investigated for the treatment of NSCLC. |
T2629 |
UNC2881
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TAM Receptor
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UNC2881 is a specific Mer tyrosine kinase inhibitor (IC50: 4.3 nM). It is about 83- and 58-fold higher selectivity than ... |
T7425 |
RU-301
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TAM Receptor
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RU-301 is a novel pan-tam inhibitor |
TQ0041 |
Ningetinib Tosylate
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c-Met/HGFR
,
TAM Receptor
,
VEGFR
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Ningetinib Tosylate is an orally bioavailable tyrosine kinase inhibitor with IC50s of <1.0, 1.9 and 6.7 nM for Axl, VEGF... |
T4426 |
CEP-40783
|
RXDX-106,CEP 40783 |
c-Met/HGFR
,
TAM Receptor
|
|
CEP-40783 is an effective, specific and orally active AXL/c-Met inhibitor (IC50: 7/12 nM). It also inhibits MER and TYRO... |
T21302 |
UNC569
|
UNC 569 |
TAM Receptor
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|
Lesinurad is a selective inhibitor of URAT1, a transporter in the kidney that regulates uric acid excretion from the bod... |
T2699 |
BMS 777607
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BMS777607,BMS-777607,BMS 817378 |
TAM Receptor
,
c-Met/HGFR
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BMS-777607 is a Met-related inhibitor for c-Met/Axl/Ron/Tyro3 (IC50: 3.9/1.1/1.8/4.3 nM). BMS-777607 has been investigat... |
TQ0021 |
Ningetinib
|
CT053PTSA,CT-053 |
VEGFR
,
TAM Receptor
,
c-Met/HGFR
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Ningetinib (CT053PTSA) is an orally bioavailable tyrosine kinase inhibitor with IC50s of <1.0, 1.9 and 6.7 nM for Axl, V... |