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Search Results for " anticancer "

Targets

1164

Compounds

308

Natural Products

22

Recombinant Proteins

19

Libraries

Cat No. Product Name Synonyms Targets
T60420 Anticancer agent 73 DNA/RNA Synthesis
Anticancer agent 73 is an anticancer agent which potently targets transactivation response(TAR) RNA-binding protein 2 (TRBP) and disrupts the TRBP-Dicer interaction. Anticancer agent 73 suppresses the growth and metasta...
T61046 Anticancer agent 43 Apoptosis
Anticancer agent 43 is a potent anticancer agent that induces apoptosis through caspase 3, PARP1, and Bax protein-dependent pathways.Anticancer agent 43 induces DNA damage and can be used in the study of glioblastoma in ...
T60852 Anticancer agent 46
Anticancer agent 46 is a potent anti-cancer agent, showing anti-proliferative activity in cellular assays, with an IC50 of 0.986 μM against MGC803 cells.
T40330 Anticancer agent 15
Anticancer agent 15, an anticancer agent, exerts its efficacy by elevating intracellular levels of reactive oxygen species (ROS) and inducing cell death in melanoma cancer cells through necroptosis.
T40479 Anticancer agent 13
Anticancer agent 13 is an anticancer agent from dicarboxylic acids and amines.
T39868 Anticancer agent 11
Anticancer agent 11 an effective broad-spectrum anticancer agent, exerts its therapeutic potential by suppressing angiogenesis and facilitating the formation of DNA cross-links.
T39501 Anticancer agent 7
Anticancer agent 7 (Example 5) is an anti-cancer agent that exhibits potent anticancer activity against H1650 lung cancer cells, with an IC50 value of 5 μM.
T10331 Anticancer agent 3 Others
Anticancer agent 3 (Compound 4) is a anti-cancer agent.
T27998 MDK-4204 Anticancer AgentI,MDK 4204,Anticancer Agent I,MDK4204,Anticancer Agent-I
MDK-4204, an anticancer agent, shows significant anti-cancer activity with IC50 values of 8.8 µM and 9.5 µM in PC-3 and DU-145 cells, respectively.
T72474 Anticancer agent 53
Anticancer agent 53 is a potent anticancer agent. Anticancer agent 53 shows in vitro cytotoxicity. Anticancer agent 53 induces apoptosis and cell cycle arrest in S/G2/M phases. Anticancer agent 53 shows antitumor activit...
T62667 Anticancer agent 51
Anticancer agent 51 (compound 3d) is a potent anticancer agent (Ki: 731.62 nM) with anticancer activity. anticancer agent 51 has potential for prostate cancer research.
T62602 Anticancer agent 49
Anticancer agent 49 (compound 69) is a broad-spectrum anticancer agent with anti-proliferative activity. anticancer agent 48 inhibits microtubule protein aggregation and has in vivo antitumour activity. anticancer agent ...
T74961 Anticancer agent 84
Anticancer agent 84 is an anticancer agent. Anticancer agent 84 represses the transcription of c-MYC by stabilizing the G-quadruplex (G4) structure. Anticancer agent 84 can be used for the research of cancer [1] .
T63522 Anticancer agent 64
Anticancer agent 64 (compound 5m) shows cytotoxic activity in CCRF-CEM cells, with IC 50 of 2.4 μM. Anticancer agent 64 shows good anticancer activity through apoptosis induction. Anticancer agent 64 induces caspase 3 an...
T72502 Anticancer agent 92
Anticancer agent 92 is an anticancer agent that is nontoxic against noncancerous cells .
T63599 Anticancer agent 54
Anticancer agent 54 is an effective anticancer agent whose anticancer activity depends on DNA embedding and ROS generation. Anticancer agent 54 has an anti-proliferative effect by blocking the cell cycle in G0/G1 phase a...
T83091 Anticancer agent 113
Anticancer agent 113 possesses anticancer activity [1].
T60776 Anticancer agent 68
Anticancer agent 68 is (Compound 12) is an anti-cancer agent. Anticancer agent 68 arrests the cells at the G2/M phase and induces programmed cell death. Anticancer agent 68 induces upregulation of tumor suppression via a...
T63587 Anticancer agent 45
Anticancer agent 46 is a potent and selective anticancer agent that induces apoptosis. anticancer agent 46 exhibits cytotoxic effects in cancer cells and shows low toxicity to activated lymphocytes of human blood.
T63489 Anticancer agent 77
Anticancer agent 77 exhibits anticancer effects and can be used extensively in synthetic and medicinal chemistry studies.
T63982 Anticancer agent 50
Anticancer agent 50 (compound 6) is a potent modulator of the ABCB1 efflux pump with cytotoxic and anti-proliferative activity. anticancer agent 50 reduces the expression of cyclin D1 and induces p53 expression. anticanc...
T61576 Anticancer agent 83
Anticancer agent 83 is a potent anticancer agent, inhibits LOX IMVI cells growth with a GI 50 value of 0.15 mM. Anticancer agent 83 reduces mitochondrial membrane potential and induces DNA damage to induces leukemia cell...
T61902 Anticancer agent 69
Anticancer agent 69 (Compound 34) is an effective selective anticancer agent with selective inhibition on human prostate cancer cell line PC3 (IC50=26 nM). Anticancer agent 69 can increase ROS level and down-regulate EGF...
T61673 Anticancer agent 56
Anticancer agent 56 (compound 4d) is a powerful anti-cancer compound with favorable drug-like properties. It shows significant anticancer activity against multiple cancer cell lines, with an IC50 value of less than 3 μM....
T83095 Anticancer agent 101
Anticancer Agent 101, a tetracaine derivative, exhibits anti-cancer activity [1].
T79247 Anticancer agent 127 IAP
Anticancer agent 127 (142D6), an IAP inhibitor, covalently binds to the BIR3 domains of XIAP, cIAP1, and cIAP2, with IC50 values of 12 nM, 14 nM, and 9 nM, respectively, demonstrating anticancer effects [1].
T83082 Anticancer agent 168
Compound D16 (Anticancer agent 168) is an inhibitor of DNA2 that induces apoptosis and cell-cycle arrest predominantly in the S-phase. It demonstrates anticancer efficacy and can counteract chemotherapy resistance in can...
T78941 Anticancer agent 130 Apoptosis
Anticancer agent 130 (compound 8d) significantly induces apoptosis in A549 cells [1].
T63830 Anticancer agent 76
Anticancer agent 76 (Compound CT2-3) is an anti-cancer agent that significantly inhibits proliferation, induces cell cycle arrest, ROS production and apoptosis in human NSCLC cells.
T78957 Anticancer agent 105 Apoptosis
Anticancer agent 105, a thienopyrimidine scaffold-based compound, exhibits selective toxicity towards melanoma and induces apoptosis. Additionally, it significantly inhibits metastatic nodules, including in a pulmonary m...
T83079 Anticancer agent 172
Anticancer agent 172 (8d) exhibits potent activity against cancer, achieving an IC50 value of 6.96 μM in HCT116 cells [1].
T79844 Anticancer agent 143 Phosphatase
Anticancer Agent 143 (Compound 369), a potent dual inhibitor targeting PTPN2 and PTP1B, exhibits IC50 values below 2.5 nM. It is employed in cancer research [1].
T83076 Anticancer agent 93
Anticancer Agent 93, a 4-Hydroxycoumarin derivative, inhibits the invasion and migration of lung cancer cells through modulation of epithelial-mesenchymal transition (EMT) effector expression [1].
T79646 Anticancer agent 153 Apoptosis
Anticancer Agent 153 (Compound 3) promotes apoptosis through the generation of Reactive Oxygen Species (ROS) and elevates the loss of Mitochondrial Membrane Potential (MMP), effectively inhibiting cancer cell proliferati...
T78742 Anticancer agent 132 Apoptosis
Compound Rh1 (Anticancer agent 132) acts as an inducer of apoptosis and autophagy, exhibiting both antitumor and antimetastatic activities. It also arrests the cell cycle and inhibits cell proliferation [1].
T79248 Anticancer agent 128 IAP
Anticancer agent 128 (compound 1) is an IAP inhibitor that covalently binds to the BIR3 domains of XIAP, cIAP1, and cIAP2, exhibiting IC50 values of 24.9 nM, 19.3 nM, and 10.3 nM, respectively [1].
T79465 Anticancer agent 135 Androgen Receptor
Anticancer agent 135 (compound 26h) acts as a potent androgen receptor (AR) antagonist, effectively blocking AR nuclear translocation and inhibiting AR/AR-V7 heterodimerization to suppress downstream gene transcription. ...
T83087 Anticancer agent 158
Anticancer agent 158 (compound 7c) demonstrates potent efficacy against various cancer cell lines, with IC50 values of 7.93 μM for HepG-2, 9.28 μM for MDA-MB-231, and 13.28 μM for HCT-116; however, it exhibits reduced po...
T79843 Anticancer agent 142 Phosphatase
Compound 142 (also known as Compound 235) is a PTPN inhibitor with potential applications in cancer research [1].
T74521 Anticancer agent 52
Anticancer agent 52 is a potent anticancer agent. Anticancer agent 52 shows in vitro cytotoxicity. Anticancer agent 52 induces apoptosis . Anticancer agent 52 shows antitumor effect. Anticancer agent 52 has the potential...
T74767 Anticancer agent 102
Anticancer agent 102 is a derivative of tetracaine. Anticancer agent 102 has anti-cancer activity. Anticancer agent 102 induces apoptosis [1] .
T62601 Anticancer agent 48
Anticancer agent 48 (compound 48) is a broad-spectrum anticancer agent with anti-proliferative activity. anticancer agent 48 inhibits microtubule protein polymerisation and has anti-tumour activity in vivo. anticancer ag...
T62044 Anticancer agent 71
Anticancer agent 71 (Compound 4b) is a potent anticancer agent. Anticancer agent 71 arrests cell cycle at G2/M phase. Anticancer agent 71 induces apoptosis through upregulating Bax, Ikb-α and cleaved PARP and downregulat...
T61230 Anticancer agent 74
Anticancer agent 74 exhibits moderate anticancer activity with lower selectivity and cytotoxicity compared to doxorubicin towards normal cells [1].
T61777 Anticancer agent 42
Anticancer agent 42 (compound 10d) is an orally active, potent anticancer agent with demonstrated efficacy against MDA-MB-231 cells, exhibiting an IC50 of 0.07 μM. It exerts its anticancer activity through the activation...
T60314 Anticancer agent 38
Anticancer agent 38 (compound 19) is an aryl-urea compound, and is a potent anticancer agent. Anticancer agent 38 inhibits A431 cell growth with an IC 50 of 5.2 μg/mL [1].
T60998 Anticancer agent 75
Anticancer agent 75 has good antiplasmodial activity. Anticancer agent 75 is a potent anticancer agent with cytotoxicity and selectivity in cancer cell lines. The cytotoxicity of Anticancer agent 75 to normal human kidne...
T61973 Anticancer agent 79
Anticancer agent 79 (compound 3d) is a anticancer compound with good anti-breast cancer activity. Anticancer agent 79 exhibits good cytotoxic activity in T47-D cells (IC50= 13.64 ± 0.26 μM).
T63759 Anticancer agent 44
Anticancer agent 44 is a potent and selective anticancer agent that induces apoptosis. anticancer agent 44 has cytotoxic activity in cancer cells and low toxicity in activated lymphocytes of human blood.
T61750 Anticancer agent 72
Anticancer agent 72 (compound 8c) effectively inhibits the K+ channel, displaying significant potential as an anticancer treatment. Additionally, it induces apoptosis, a programmed cell death process [1].

Compounds

Anticancer agent 73
T60420
Synonym:
Target: DNA/RNA Synthesis
Anticancer agent 43
T61046
Synonym:
Target: Apoptosis
Anticancer agent 46
T60852
Synonym:
Target:
Anticancer agent 15
T40330
Synonym:
Target:
Anticancer agent 13
T40479
Synonym:
Target:
Anticancer agent 11
T39868
Synonym:
Target:
Anticancer agent 7
T39501
Synonym:
Target:
Anticancer agent 3
T10331
Synonym:
Target: Others
MDK-4204
T27998
Synonym: Anticancer AgentI,MDK 4204,Anticancer Agent I,MDK4204,Anticancer Agent-I
Target:
Anticancer agent 53
T72474
Synonym:
Target:
Anticancer agent 51
T62667
Synonym:
Target:
Anticancer agent 49
T62602
Synonym:
Target:
Anticancer agent 84
T74961
Synonym:
Target:
Anticancer agent 64
T63522
Synonym:
Target:
Anticancer agent 92
T72502
Synonym:
Target:
Anticancer agent 54
T63599
Synonym:
Target:
Anticancer agent 113
T83091
Synonym:
Target:
Anticancer agent 68
T60776
Synonym:
Target:
Anticancer agent 45
T63587
Synonym:
Target:
Anticancer agent 77
T63489
Synonym:
Target:
Anticancer agent 50
T63982
Synonym:
Target:
Anticancer agent 83
T61576
Synonym:
Target:
Anticancer agent 69
T61902
Synonym:
Target:
Anticancer agent 56
T61673
Synonym:
Target:
Anticancer agent 101
T83095
Synonym:
Target:
Anticancer agent 127
T79247
Synonym:
Target: IAP
Anticancer agent 168
T83082
Synonym:
Target:
Anticancer agent 130
T78941
Synonym:
Target: Apoptosis
Anticancer agent 76
T63830
Synonym:
Target:
Anticancer agent 105
T78957
Synonym:
Target: Apoptosis
Anticancer agent 172
T83079
Synonym:
Target:
Anticancer agent 143
T79844
Synonym:
Target: Phosphatase
Anticancer agent 93
T83076
Synonym:
Target:
Anticancer agent 153
T79646
Synonym:
Target: Apoptosis
Anticancer agent 132
T78742
Synonym:
Target: Apoptosis
Anticancer agent 128
T79248
Synonym:
Target: IAP
Anticancer agent 135
T79465
Synonym:
Target: Androgen Receptor
Anticancer agent 158
T83087
Synonym:
Target:
Anticancer agent 142
T79843
Synonym:
Target: Phosphatase
Anticancer agent 52
T74521
Synonym:
Target:
Anticancer agent 102
T74767
Synonym:
Target:
Anticancer agent 48
T62601
Synonym:
Target:
Anticancer agent 71
T62044
Synonym:
Target:
Anticancer agent 74
T61230
Synonym:
Target:
Anticancer agent 42
T61777
Synonym:
Target:
Anticancer agent 38
T60314
Synonym:
Target:
Anticancer agent 75
T60998
Synonym:
Target:
Anticancer agent 79
T61973
Synonym:
Target:
Anticancer agent 44
T63759
Synonym:
Target:
Anticancer agent 72
T61750
Synonym:
Target:
1 2 3 4 5 ... 24
Cat No. Product Name Synonyms Targets
T83086 Anticancer agent 160
Anticancer agent 160 (Compound 6), a natural product extracted from Parthenium hysterophorus, exhibits cytotoxicity against HCT-116 cells with an IC50 of 5.0 μM [1].
T83073 Anticancer agent 96
Anticancer Agent 96 (Compound 4) exhibits cytotoxic activities against human cancer cells [1].
T83088 Anticancer agent 156
Compound 156, also referred to as compound 11, is a potent miliusanes-based anticancer agent that demonstrates effective inhibition of human cancer cell growth and exhibits substantial cytotoxicity against gastric cancer...
T83089 Anticancer agent 149
Anticancer Agent 149 (compound 3), isolated from the rhizome of Dioscorea dioscorea (DM), demonstrates selective cytotoxicity against MCF-7 cells with an IC50 of 31.41 μM [1].
T9144 Telekin Others
Telekin, a eudesmane-type sesquiterpene lactone compound isolated from Chinese folk medicine Carpesium divaricatum, has been reported to strongly inhibit the proliferation of cancer cells
TN1873 Lirinidine Others
(+)-Lirinidine has antioxidative activity, and it can significantly inhibit the proliferation of melanoma cells; it also shows potent inhibition of melanogenesis. Lirinidine exhibits significant inhibition of collagen, a...
T21065 Artemisitene Others
Artemisitene is the oxidized form of Artemisinin and is an antimalarial agent. Artemisinin precursors are the important basic substances for biosynthesis of Artemisinin, including Artemisinin B, Artemisitene, Artemisini...
TN6771 Malabaricone B Others
Malabaricone B is a Spice-derived phenolic, it induces mitochondrial damage in lung cancer cells via a p53-independent pathway.
T10668 Camalexin Reactive Oxygen Species , ROS , Antibacterial , Antifungal
Camalexin is a phytoalexin isolated from Camelina sativa. It has antifungal, antibacterial, antiproliferative, and anticancer activities. Camalexin can induce ROS production.
TN6739 Angoline 6-Methoxyldihydrochelerythrine IL Receptor , STAT
Angoline (6-Methoxyldihydrochelerythrine) hydrochloride is a potent and selective IL6/STAT3 signaling pathway inhibitor(IC50 : 11.56 μM). It inhibits STAT3 phosphorylation and its target gene expression, and inhibits can...
TN1079 Deoxyelephantopin NF-κB
Deoxyelephantopin has anti-inflammatory, hepatoprotective, and wound healing activities; it also has antitumor activity.Deoxyelephantopin inhibits NF-κB, MAPK, PI3K/Akt, and β-catenin signaling
TN7060 Methyl oleanonate PPAR
3-Oxoolean-12-en-28-oic acid methyl ester is a triterpenoid PPARγ agonist isolated from Pistacia with anticancer properties.
T7052 Gnetol Tyrosinase , COX , HDAC , AChR
Gnetol competitivity inhibits butyrylcholinesterase (IC50: 1.3 uM). Gnetol has a strong inhibitory effect on murine tyrosinase activity. Gnetol significantly suppresses melanin biosynthesis in murine B16 melanoma cells. ...
T2853 Curcumol (-)-Curcumol Apoptosis , JAK
Curcumol ((-)-Curcumol), a pure monomer isolated extracted from Rhizoma Curcumaeis, has antitumor activities.
TN1712 Gossypin NF-κB , S6 Kinase
Gossypin has antidiabetic, antioxdiant, anticonvulsant, anti-allergic, antiinflammatory, antinociceptive, cytotoxic and antibacterial activities; it inhibits the NF-kappaB activation pathway, which may explain its role i...
T7544 Fucoidan Others
Fucoidan is found in various species of brown seaweed and algae,with anticancer, antiviral, neuroprotective, immune-modulating.
T11685 Isolongifolene (-)-Isolongifolene Apoptosis , Others
Isolongifolene ((-)-Isolongifolene) has antioxidant, anti-inflammatory, anticancer and neuroprotective properties. Isolongifolene is a tricyclic sesquiterpene isolated from Murraya koenigii. Isolongifolene attenuates Rot...
T9715 Aplidine SARS-CoV , DNA/RNA Synthesis
Aplidine possesses antiviral activity against SARS-CoV-2(IC90 = 0.88 nM). Aplidine is a potent anti-cancer agent by targeting eukaryotic translation elongation factor 1 Alpha 2(EEF1A2, Kd = 80 nM).
T3332 Isosteviol (-)-Isosteviol IL Receptor , Potassium Channel , TNF , NF-κB , Reactive Oxygen Species , COX , Topoisomerase
Isosteviol ((-)-Isosteviol), a common natural sweetener, belongs to tetracyclic diterpene glycosides. The pharmacology researches have suggested that stevioside and its hydrolysis products, steviol, isosteviol and stevio...
T2731 Usnic Acid Usniacin Antibacterial , Autophagy
Usnic Acid (Usniacin) is an antimicrobial, antitumor and enzyme inhibiting agent shown to uncouple oxidative phosphorylation in mouse-liver mitochondria. Usnic acid induces necrosis in certain cells.
T1134 Clofoctol Antibacterial , Antibiotic
Clofoctol is a bacteriostatic antibiotic with activity against Gram-positive bacteria, used in the treatment of upper and lower respiratory tract infections.
T5613 Squalane Dodecahydrosqualene,Perhydrosqualene Others
Squalane (Perhydrosqualene) is a naturally occurring lipid in both plants and animals. It is usually used as a moisturizer and emollient in cosmetics manufacturing.
TN1990 Norathyriol 芒果 Akt , DNA/RNA Synthesis , AMPK , PPAR
Norathyriol is a potent PTP1B inhibitor with good cell permeability and oral availability.
TN1727 Helichrysetin Apoptosis , HIV Protease
Helichrysetin has mild anti-HIV-1 PR activity. Helichrysetin has great potentials for development as an anticancer agent, it has cytotoxic effect on four selected cancer cell lines, A549, MCF-7, Ca Ski, and HT-29.
T7730 Aminopterin APGA,4-Aminofolic acid Antifolate
Aminopterin (4-Aminofolic acid) is a synthetic folic acid derivative whose metabolite is a competitive inhibitor of dihydrofolate reductase
T3921 Punicalagin SARS-CoV , HBV
Punicalagin is a major ellagitannin found in pomegranates that is reported to produce antioxidant, anti-inflammatory, and anticancer effects. It has been shown to prevent high-fat diet-induced obesity-associated accumula...
T6995 Ochromycinone STA 21,STA21,STA-21 Antibacterial , STAT
Ochromycinone (STA 21) is a selective STAT3 inhibitor.
TN7059 Deoxylimonin NSC 314317,desoxylimonin Others
Deoxylimonin (NSC 314317) is a triterpenoid isolated from grapefruit seeds.
T3912 Saikosaponin B1 Others
Saponin activator. Activates release of Prostaglandin E2 in vitro. Anti-inflammatory agent. Orally active. Active in vivo and in vitro.
T2800 L-Theanine Apoptosis , Others
L-Theanine is a relaxing and nondietary amino acid found pretty much exclusively in teas from Camellia sinensis and is known to promote relaxation without sedation.
T5S0055 Chelidonine Helidonine,Khelidonin,Stylophorin Apoptosis , Others , Influenza Virus
1. Chelidonine (Stylophorin) isolated from Chelidonium majus efficiently induced apoptosis in HeLa cells through possible alteration of p38-p53 and AKT/PI3 kinase signalling pathways. 2. Chelidonine is a promising model ...
T0610 Piceatannol trans-Piceatannol,Astringenin Apoptosis , Serine/threonin kinase , PKA , Syk , PKC , Autophagy
Piceatannol (Astringenin) is an anti-inflammatory, immunomodulatory and antiproliferative agent. It inhibits p56lck and syk protein tyrosine kinases and inhibits NF-κB activation and gene expression of TNF-induced. It is...
T2230 Paeoniflorin Peoniflorin HSP , COX
Paeoniflorin (Peoniflorin) is a herbal constituent extracted from the root of Paeonia albiflora Pall.
TN1195 17-Hydroxy sprengerinin C 17-羟基 SPRENGERININ C BCL , Others , Caspase
17-Hydroxy sprengerinin C is a glycoside compound isolated from rhizomes of Polygonatum sibiricum with stronger anticancer activities. 17-Hydroxy sprengerinin C reduces the expression of Blc-2 and pro-caspase3 and increa...
T6431 Levoleucovorin Calcium Calcium Levofolinate,CL307782 Others , Antifolate
Levoleucovorin Calcium (CL307782), a calcium salt of the folinic acid, is used in cancer chemotherapy as an adjuvant.
T6169 Indirubin Indigopurpurin,Indigo red,NSC 105327,Couroupitine B Apoptosis , Raf , GSK-3 , CDK
Indirubin (Couroupitine B) is a potent cyclin-dependent kinases and GSK-3β inhibitor with IC50 of about 5 uM and 0.6 uM.
T4S0094 Hydroxygenkwanin Luteolin 7-methylether,7-O-Methylluteolin Antioxidant
1. Hydroxygenkwanin (Luteolin 7-methylether) possesses significant the antioxidative activity . 2. Hydroxygenkwanin has cytotoxicity, may be an effective natural product to treat glioma, and the combination of Apigenin a...
T1011 Itraconazole R51211 P450 , Hedgehog/Smoothened , Antibiotic , Autophagy , Antifungal
Itraconazole (R51211) is a triazole antifungal agent that inhibits cytochrome P-450-dependent enzymes required for ERGOSTEROL synthesis.
T1611 Isotretinoin 13-cis-Retinoic acid Retinoid Receptor , Endogenous Metabolite , Autophagy
Isotretinoin (13-cis-Retinoic acid) binds to and activates nuclear retinoic acid receptors (RARs); activated RARs serve as transcription factors that promote cell differentiation and apoptosis. Isotretinoin is a naturall...
T2763 Panaxadiol 20(R)-Panaxadiol Others , HIF/HIF Prolyl-Hydroxylase
Panaxadiol (20(R)-Panaxadiol) is a novel antitumor agent extracted from the Chinese medical herb Panax ginseng.
T2S0961 Chalcone benzylideneacetophenone,phenyl styryl ketone,Cinnamophenone,benzalacetophenone,β-phenylacrylophenone EGFR , Antibacterial
Chalcone (Cinnamophenone) is an aromatic ketone that forms the central core for a variety of important biological compounds, which are known collectively as chalcones.
T7786 Tryptanthrin DNA gyrase
Tryptanthrin is a natural DNA gyrase inhibitor.
T5668 Triacetylresveratrol Acetyl-trans-resveratrol BCL , NF-κB , STAT
Triacetylresveratrol (Acetyl-trans-resveratrol) has anti-cancer activity,it inhibits the phosphorylation of STAT3 and NFκB, down-regulates Mcl-1, and up-regulates Bim and Puma in pancreatic cancer cells.
T4S21320 ISOGINKGETIN 4',4'''-Dimethylamentoflavone MMP , Others
1. ISOGINKGETIN (4',4'''-Dimethylamentoflavone), a compound derived from the leaves of Ginkgo biloba, to up-regulate adiponectin secretion with potency comparable to that of rosiglitazone, a known modulator of adiponecti...
T2902 Costunolide Costus lactone,NSC 106404,Costunolid,(+)-Costunolide Apoptosis , Endogenous Metabolite , Telomerase
Costunolide (Costus lactone) has anti-inflammatory and anti-oxidant properties and mediates apoptosis.
T0687 Simvastatin MK-0733,MK 733 Apoptosis , Mitophagy , Ferroptosis , HMG-CoA Reductase , Autophagy
Simvastatin (MK 733) is a HMG-CoA Reductase Inhibitor. The mechanism of action of simvastatin is as a Hydroxymethylglutaryl-CoA Reductase Inhibitor.
T3604 Sodium dichloroacetate Sodium Dichloroacetate,DCA,BCA,bichloroacetic acid,Sodium dichloroacetate (DCA) Apoptosis , Dehydrogenase , Reactive Oxygen Species , PDK
Sodium dichloroacetate (BCA) , a specific inhibitor of pyruvate dehydrogenase kinase (PDK) with IC50 values of 183 and 80 μM for PDK2 and PDK4 respectively, has been shown to derepress a mitochondrial potassium-ion chann...
T4036 Solasodine Solancarpidine,Purapuridine,Solasodin Apoptosis , Others , E1/E2/E3 Enzyme , Antifungal
Solasodine (Purapuridine)(Purapuridine) is a poisonous alkaloid chemical compound that occurs in plants of the Solanaceae family. Solasodine showed selective cytotoxicity against cervical cancer cell line (HeLa) and huma...
T2755 Rhoifolin Apigenin-7-O-rhamnoglucoside,Apigenin 7-O-neohesperidoside,Rhoifoloside Others , p38 MAPK , NF-κB , transporter , IGF-1R , Autophagy
Rhoifolin (Apigenin 7-O-neohesperidoside) is extracted from Turpinia arguya Seem dried leaves.
T7064 Valproic Acid Sodium valproate,2-Propylpentanoic Acid,VPA,Depakine,2-Propylvaleric Acid Mitophagy , Gamma-secretase , HIV Protease , GABA Receptor , Sodium Channel , HDAC , Autophagy
Valproic Acid (2-Propylpentanoic Acid) is a branched chain fatty acid which potentially enhances central GABAergic neurotransmission and inhibits Na+ channels. Currently, the various molecular mechanisms of action of Val...
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Natural Products

Anticancer agent 160
T83086
Synonym:
Target:
Anticancer agent 96
T83073
Synonym:
Target:
Anticancer agent 156
T83088
Synonym:
Target:
Anticancer agent 149
T83089
Synonym:
Target:
Telekin
T9144
Synonym:
Target: Others
Lirinidine
TN1873
Synonym:
Target: Others
Artemisitene
T21065
Synonym:
Target: Others
Malabaricone B
TN6771
Synonym:
Target: Others
Camalexin
T10668
Synonym:
Target: Reactive Oxygen Species, ROS, Antibacterial, Antifungal
Angoline
TN6739
Synonym: 6-Methoxyldihydrochelerythrine
Target: IL Receptor, STAT
Deoxyelephantopin
TN1079
Synonym:
Target: NF-κB
Methyl oleanonate
TN7060
Synonym:
Target: PPAR
Gnetol
T7052
Synonym:
Target: Tyrosinase, COX, HDAC, AChR
Curcumol
T2853
Synonym: (-)-Curcumol
Target: Apoptosis, JAK
Gossypin
TN1712
Synonym:
Target: NF-κB, S6 Kinase
Fucoidan
T7544
Synonym:
Target: Others
Isolongifolene
T11685
Synonym: (-)-Isolongifolene
Target: Apoptosis, Others
Aplidine
T9715
Synonym:
Target: SARS-CoV, DNA/RNA Synthesis
Isosteviol
T3332
Synonym: (-)-Isosteviol
Target: IL Receptor, Potassium Channel, TNF, NF-κB, Reactive Oxygen Species, COX, Topoisomerase
Usnic Acid
T2731
Synonym: Usniacin
Target: Antibacterial, Autophagy
Clofoctol
T1134
Synonym:
Target: Antibacterial, Antibiotic
Squalane
T5613
Synonym: Dodecahydrosqualene,Perhydrosqualene
Target: Others
Norathyriol
TN1990
Synonym: 芒果
Target: Akt, DNA/RNA Synthesis, AMPK, PPAR
Helichrysetin
TN1727
Synonym:
Target: Apoptosis, HIV Protease
Aminopterin
T7730
Synonym: APGA,4-Aminofolic acid
Target: Antifolate
Punicalagin
T3921
Synonym:
Target: SARS-CoV, HBV
Ochromycinone
T6995
Synonym: STA 21,STA21,STA-21
Target: Antibacterial, STAT
Deoxylimonin
TN7059
Synonym: NSC 314317,desoxylimonin
Target: Others
Saikosaponin B1
T3912
Synonym:
Target: Others
L-Theanine
T2800
Synonym:
Target: Apoptosis, Others
Chelidonine
T5S0055
Synonym: Helidonine,Khelidonin,Stylophorin
Target: Apoptosis, Others, Influenza Virus
Piceatannol
T0610
Synonym: trans-Piceatannol,Astringenin
Target: Apoptosis, Serine/threonin kinase, PKA, Syk, PKC, Autophagy
Paeoniflorin
T2230
Synonym: Peoniflorin
Target: HSP, COX
17-Hydroxy sprengerinin C
TN1195
Synonym: 17-羟基 SPRENGERININ C
Target: BCL, Others, Caspase
Levoleucovorin Calcium
T6431
Synonym: Calcium Levofolinate,CL307782
Target: Others, Antifolate
Indirubin
T6169
Synonym: Indigopurpurin,Indigo red,NSC 105327,Couroupitine B
Target: Apoptosis, Raf, GSK-3, CDK
Hydroxygenkwanin
T4S0094
Synonym: Luteolin 7-methylether,7-O-Methylluteolin
Target: Antioxidant
Itraconazole
T1011
Synonym: R51211
Target: P450, Hedgehog/Smoothened, Antibiotic, Autophagy, Antifungal
Isotretinoin
T1611
Synonym: 13-cis-Retinoic acid
Target: Retinoid Receptor, Endogenous Metabolite, Autophagy
Panaxadiol
T2763
Synonym: 20(R)-Panaxadiol
Target: Others, HIF/HIF Prolyl-Hydroxylase
Chalcone
T2S0961
Synonym: benzylideneacetophenone,phenyl styryl ketone,Cinnamophenone,benzalacetophenone,β-phenylacrylophenone
Target: EGFR, Antibacterial
Tryptanthrin
T7786
Synonym:
Target: DNA gyrase
Triacetylresveratrol
T5668
Synonym: Acetyl-trans-resveratrol
Target: BCL, NF-κB, STAT
ISOGINKGETIN
T4S21320
Synonym: 4',4'''-Dimethylamentoflavone
Target: MMP, Others
Costunolide
T2902
Synonym: Costus lactone,NSC 106404,Costunolid,(+)-Costunolide
Target: Apoptosis, Endogenous Metabolite, Telomerase
Simvastatin
T0687
Synonym: MK-0733,MK 733
Target: Apoptosis, Mitophagy, Ferroptosis, HMG-CoA Reductase, Autophagy
Sodium dichloroacetate
T3604
Synonym: Sodium Dichloroacetate,DCA,BCA,bichloroacetic acid,Sodium dichloroacetate (DCA)
Target: Apoptosis, Dehydrogenase, Reactive Oxygen Species, PDK
Solasodine
T4036
Synonym: Solancarpidine,Purapuridine,Solasodin
Target: Apoptosis, Others, E1/E2/E3 Enzyme, Antifungal
Rhoifolin
T2755
Synonym: Apigenin-7-O-rhamnoglucoside,Apigenin 7-O-neohesperidoside,Rhoifoloside
Target: Others, p38 MAPK, NF-κB, transporter, IGF-1R, Autophagy
Valproic Acid
T7064
Synonym: Sodium valproate,2-Propylpentanoic Acid,VPA,Depakine,2-Propylvaleric Acid
Target: Mitophagy, Gamma-secretase, HIV Protease, GABA Receptor, Sodium Channel, HDAC, Autophagy

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-05033 5T4/TPBG Protein, Human, Recombinant (aa 60-345, His) Human HEK293
Trophoblast glycoprotein (TPBG), also known as 5T4, is the therapeutic target of several anticancer agents currently in clinical development, largely due to its high expression in tumors and low expression in normal adul...
TMPY-04644 PDGFB Protein, Human, Recombinant (His) Human Yeast
Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionalit...
TMPY-06191 5T4/TPBG Protein, Mouse, Recombinant (His) Mouse HEK293
Trophoblast glycoprotein (TPBG), also known as 5T4, is the therapeutic target of several anticancer agents currently in clinical development, largely due to its high expression in tumors and low expression in normal adul...
TMPY-06214 5T4/TPBG Protein, Mouse, Recombinant (hFc) Mouse HEK293
Trophoblast glycoprotein (TPBG), also known as 5T4, is the therapeutic target of several anticancer agents currently in clinical development, largely due to its high expression in tumors and low expression in normal adul...
TMPY-06317 5T4/TPBG Protein, Human, Recombinant (aa 1-355, His) Human HEK293
Trophoblast glycoprotein (TPBG), also known as 5T4, is the therapeutic target of several anticancer agents currently in clinical development, largely due to its high expression in tumors and low expression in normal adul...
TMPK-01310 Syndecan-1 Protein, Rabbit, Recombinant (His) Rabbit HEK293
CD138 (syndecan-1, Sdc-1) is a member of the syndecan family that comprises heparan sulfate proteoglycans. CD138 is significant for cell-cell and cell-matrix interactions.CD138 plays a crucial role in carcinogenesis and ...
TMPK-00721 CX3CL1/Fractalkine Protein, Mouse, Recombinant (His & Avi), Biotinylated Mouse HEK293
Fractalkine/CX3C chemokine ligand 1 (CX3CL1) is a chemokine involved in the anticancer function of lymphocytes-mainly NK cells, T cells and dendritic cells. Its increased levels in tumors improve the prognosis for cancer...
TMPY-02395 PDGFB Protein, Cynomolgus, Recombinant (mFc) Cynomolgus HEK293
Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionalit...
TMPY-05077 PDGFB Protein, Rhesus, Recombinant (His) Rhesus Yeast
Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionalit...
TMPY-04877 PDGFB Protein, Mouse, Recombinant (His) Mouse Yeast
Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionalit...
TMPY-05076 PDGFB Protein, Canine, Recombinant (His) Canine Yeast
Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionalit...
TMPK-00710 Claudin-4 Protein-VLP, Human, Recombinant Human HEK293
Claudin-4 (CLDN4) is a key component of tight junctions (TJs) in epithelial cells. CLDN4 is overexpressed in many epithelial malignancies and correlates with cancer progression. Changes in CLDN4 expression have been asso...
TMPK-00060 IL-17B Protein, Mouse, Recombinant (His) Mouse E. coli
IL-17A, the prototypic member of the IL-17 family, several experimental findings strongly support the role of the IL-17B/IL-17 receptor B (IL-17RB) pathway in tumorigenesis and resistance to anticancer therapies. IL-17B/...
TMPJ-00247 METAP1 Protein, Human, Recombinant Human E. coli
Methionine Aminopeptidase 1 is a member of the M24 family of metalloproteases. METAP1 plays an important role in G(2)/M phase regulation of the cell cycle and may serve as a promising target for the discovery and develop...
TMPY-00324 METAP1 Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
Processing of the N-terminal initiator methionine or formylated methionine is an essential cellular process conserved from prokaryotes to eukaryotes. The proteolytic removal of N-terminal methionine from nascent peptides...
TMPY-00883 METAP1 Protein, Human, Recombinant (hFc) Human HEK293
Processing of the N-terminal initiator methionine or formylated methionine is an essential cellular process conserved from prokaryotes to eukaryotes. The proteolytic removal of N-terminal methionine from nascent peptides...
TMPY-01865 BLMH Protein, Mouse, Recombinant (His) Mouse E. coli
The papain superfamily member bleomycin hydrolase (BLMH) is a cytoplasmic cysteine peptidase that is highly conserved through evolution. The only known activity of the enzyme is metabolic inactivation of the glycopeptide...
TMPY-04143 Chemerin/RARRES2 Protein, Mouse, Recombinant (hFc) Mouse HEK293
Retinoic acid receptor responder protein 2 (RARRES2) is a small secreted protein involved in multiple cancers, including adrenocortical carcinoma (ACC). Serum RARRES2 may be used as a novel prognostic marker for ACC. Ret...
TMPY-00367 Chemerin/RARRES2 Protein, Mouse, Recombinant (His) Mouse HEK293
Retinoic acid receptor responder protein 2 (RARRES2) is a small secreted protein involved in multiple cancers, including adrenocortical carcinoma (ACC). Serum RARRES2 may be used as a novel prognostic marker for ACC. Ret...
TMPY-02072 HSF1 Protein, Human, Recombinant (His) Human E. coli
Heat shock factor protein 1, also known as heat shock transcription factor 1, HSF1, and HSTF1, is a cytoplasm and nucleus protein that belongs to the HSF family. HSF1 is the major transcription factor of HSPs (heat shock...
TMPY-02076 PIN1 Protein, Human, Recombinant (His) Human E. coli
Peptidyl-prolyl cis-trans isomerase Pin1, also known as Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, Rotamase Pin1 and PIN1, peptidyl-prolyl cis/trans isomerase (PPIase), is a nucleus protein. PIN1 is a peptid...
TMPY-02114 PIN1 Protein, Human, Recombinant Human E. coli
Peptidyl-prolyl cis-trans isomerase Pin1, also known as Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, Rotamase Pin1 and PIN1, peptidyl-prolyl cis/trans isomerase (PPIase), is a nucleus protein. PIN1 is a peptid...
5T4/TPBG Protein, Human, Recombinant (aa 60-345, His)
TMPY-05033
Species: Human
Expression System: HEK293
PDGFB Protein, Human, Recombinant (His)
TMPY-04644
Species: Human
Expression System: Yeast
5T4/TPBG Protein, Mouse, Recombinant (His)
TMPY-06191
Species: Mouse
Expression System: HEK293
5T4/TPBG Protein, Mouse, Recombinant (hFc)
TMPY-06214
Species: Mouse
Expression System: HEK293
5T4/TPBG Protein, Human, Recombinant (aa 1-355, His)
TMPY-06317
Species: Human
Expression System: HEK293
Syndecan-1 Protein, Rabbit, Recombinant (His)
TMPK-01310
Species: Rabbit
Expression System: HEK293
CX3CL1/Fractalkine Protein, Mouse, Recombinant (His & Avi), Biotinylated
TMPK-00721
Species: Mouse
Expression System: HEK293
PDGFB Protein, Cynomolgus, Recombinant (mFc)
TMPY-02395
Species: Cynomolgus
Expression System: HEK293
PDGFB Protein, Rhesus, Recombinant (His)
TMPY-05077
Species: Rhesus
Expression System: Yeast
PDGFB Protein, Mouse, Recombinant (His)
TMPY-04877
Species: Mouse
Expression System: Yeast
PDGFB Protein, Canine, Recombinant (His)
TMPY-05076
Species: Canine
Expression System: Yeast
Claudin-4 Protein-VLP, Human, Recombinant
TMPK-00710
Species: Human
Expression System: HEK293
IL-17B Protein, Mouse, Recombinant (His)
TMPK-00060
Species: Mouse
Expression System: E. coli
METAP1 Protein, Human, Recombinant
TMPJ-00247
Species: Human
Expression System: E. coli
METAP1 Protein, Human, Recombinant (His)
TMPY-00324
Species: Human
Expression System: Baculovirus-Insect Cells
METAP1 Protein, Human, Recombinant (hFc)
TMPY-00883
Species: Human
Expression System: HEK293
BLMH Protein, Mouse, Recombinant (His)
TMPY-01865
Species: Mouse
Expression System: E. coli
Chemerin/RARRES2 Protein, Mouse, Recombinant (hFc)
TMPY-04143
Species: Mouse
Expression System: HEK293
Chemerin/RARRES2 Protein, Mouse, Recombinant (His)
TMPY-00367
Species: Mouse
Expression System: HEK293
HSF1 Protein, Human, Recombinant (His)
TMPY-02072
Species: Human
Expression System: E. coli
PIN1 Protein, Human, Recombinant (His)
TMPY-02076
Species: Human
Expression System: E. coli
PIN1 Protein, Human, Recombinant
TMPY-02114
Species: Human
Expression System: E. coli
Cat No. Product Name
L2180 Anti-Cancer Compound Library Plus

1468 compounds
Well-chosen 1468 anti-tumor compounds with unique structures;
L2150 Anti-Cancer Drug Library

3159 compounds
A unique collection of 3159 anticancer drugs for high throughput screening (HTS) and high content screening (HCS);
L2100 Anti-Cancer Compound Library

7360 compounds
A unique collection of 7360 compounds with anti-cancer activity for high throughput screening (HTS) and high content screening (HCS);
L2160 Anti-Cancer Active Compound Library

3250 compounds
A unique collection of 3250 compounds with known anti-cancer activity for high throughput screening (HTS) and high content screening (HCS);
L2110 Anti-Cancer Approved Drug Library

1825 compounds
A unique collection of 1825 approved anti-cancer drugs for high throughput screening (HTS) and high content screening (HCS);
L2120 Anti-Cancer Clinical Compound Library

2614 compounds
A unique collection of 2614 anti-cancer compounds for high throughput screening (HTS) and high content screening (HCS);
L2130 Anti-Cancer Metabolism Compound Library

1280 compounds
A unique collection of 1280 cancer cellular metabolism related compounds for cancer research and high throughput screening (HTS) and high content screening (HCS);
L2151 Chemotherapy Drug Library

51 compounds
51 Chemotherapeutic drugs that can be used for high-throughput and high-content screening.
L1110 Microtubule-Targeted Compound Library

155 compounds
A unique collection of 155 microtubule-targeted compounds can be used in HTS and HCS;
L6110 Alkaloid Natural Product Library

468 compounds
A unique collection of 468 natural alkaloids can be used for high throughput and high content screening;
NY1000 Natural Product Derivatives Library

4000 compounds
The library consists of more than 4,000 members belonging 22 scaffolds (average 180 compounds per scaffold).
L6100 Polyphenolic Natural Product Library

640 compounds
A unique collection of 640 natural polyphenolic compounds for high throughput screening (HTS) and high content screening (HCS);
L6130 Terpene Natural Product Library

522 compounds
A unique collection of 522 natural terpenes and terpenoids can be used for high throughput and high content screening;
L6900 Rare Natural Product Library

180 compounds
A unique collection of 180 rare natural products, which can be used for high throughput screening (HTS) and high content screening (HCS);
L1100 Protease Inhibitor Library

344 compounds
A unique collection of 344 protease and proteasome inhibitors for research in chemical genomics, and drug screening;
L6700 Anti-Tumor Natural Product Library

1800 compounds
A unique collection of 1800 natural products with known anti-cancer activity for high throughput screening (HTS) and high content screening (HCS);
L5100 Fluorochemical Library

583 compounds
A unique collection of 583 fluorochemicals that can be used for high through-put screening (HTS) and high content screening (HCS);
L6020 Selectable Natural Product Library

16627 compounds
A unique collection of 16627 pure natural products with diverse structures and sources covering various plant, animal, and microbe species;
L6820 Tobacco Monomer Library

750 compounds
A unique collection of 750 tobacco monomer compounds for high throughput screening and high content screening;
TargetMol