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Cat No. | Product Name | Synonyms | Targets |
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T60420 | Anticancer agent 73 | DNA/RNA Synthesis | |
Anticancer agent 73 is an anticancer agent which potently targets transactivation response(TAR) RNA-binding protein 2 (TRBP) and disrupts the TRBP-Dicer interaction. Anticancer agent 73 suppresses the growth and metasta... | |||
T61046 | Anticancer agent 43 | Apoptosis | |
Anticancer agent 43 is a potent anticancer agent that induces apoptosis through caspase 3, PARP1, and Bax protein-dependent pathways.Anticancer agent 43 induces DNA damage and can be used in the study of glioblastoma in ... | |||
T60852 | Anticancer agent 46 | ||
Anticancer agent 46 is a potent anti-cancer agent, showing anti-proliferative activity in cellular assays, with an IC50 of 0.986 μM against MGC803 cells. | |||
T40330 | Anticancer agent 15 | ||
Anticancer agent 15, an anticancer agent, exerts its efficacy by elevating intracellular levels of reactive oxygen species (ROS) and inducing cell death in melanoma cancer cells through necroptosis. | |||
T40479 | Anticancer agent 13 | ||
Anticancer agent 13 is an anticancer agent from dicarboxylic acids and amines. | |||
T39868 | Anticancer agent 11 | ||
Anticancer agent 11 an effective broad-spectrum anticancer agent, exerts its therapeutic potential by suppressing angiogenesis and facilitating the formation of DNA cross-links. | |||
T39501 | Anticancer agent 7 | ||
Anticancer agent 7 (Example 5) is an anti-cancer agent that exhibits potent anticancer activity against H1650 lung cancer cells, with an IC50 value of 5 μM. | |||
T10331 | Anticancer agent 3 | Others | |
Anticancer agent 3 (Compound 4) is a anti-cancer agent. | |||
T27998 | MDK-4204 | Anticancer AgentI,MDK 4204,Anticancer Agent I,MDK4204,Anticancer Agent-I | |
MDK-4204, an anticancer agent, shows significant anti-cancer activity with IC50 values of 8.8 µM and 9.5 µM in PC-3 and DU-145 cells, respectively. | |||
T72474 | Anticancer agent 53 | ||
Anticancer agent 53 is a potent anticancer agent. Anticancer agent 53 shows in vitro cytotoxicity. Anticancer agent 53 induces apoptosis and cell cycle arrest in S/G2/M phases. Anticancer agent 53 shows antitumor activit... | |||
T62667 | Anticancer agent 51 | ||
Anticancer agent 51 (compound 3d) is a potent anticancer agent (Ki: 731.62 nM) with anticancer activity. anticancer agent 51 has potential for prostate cancer research. | |||
T62602 | Anticancer agent 49 | ||
Anticancer agent 49 (compound 69) is a broad-spectrum anticancer agent with anti-proliferative activity. anticancer agent 48 inhibits microtubule protein aggregation and has in vivo antitumour activity. anticancer agent ... | |||
T74961 | Anticancer agent 84 | ||
Anticancer agent 84 is an anticancer agent. Anticancer agent 84 represses the transcription of c-MYC by stabilizing the G-quadruplex (G4) structure. Anticancer agent 84 can be used for the research of cancer [1] . | |||
T63522 | Anticancer agent 64 | ||
Anticancer agent 64 (compound 5m) shows cytotoxic activity in CCRF-CEM cells, with IC 50 of 2.4 μM. Anticancer agent 64 shows good anticancer activity through apoptosis induction. Anticancer agent 64 induces caspase 3 an... | |||
T72502 | Anticancer agent 92 | ||
Anticancer agent 92 is an anticancer agent that is nontoxic against noncancerous cells . | |||
T63599 | Anticancer agent 54 | ||
Anticancer agent 54 is an effective anticancer agent whose anticancer activity depends on DNA embedding and ROS generation. Anticancer agent 54 has an anti-proliferative effect by blocking the cell cycle in G0/G1 phase a... | |||
T83091 | Anticancer agent 113 | ||
Anticancer agent 113 possesses anticancer activity [1]. | |||
T60776 | Anticancer agent 68 | ||
Anticancer agent 68 is (Compound 12) is an anti-cancer agent. Anticancer agent 68 arrests the cells at the G2/M phase and induces programmed cell death. Anticancer agent 68 induces upregulation of tumor suppression via a... | |||
T63587 | Anticancer agent 45 | ||
Anticancer agent 46 is a potent and selective anticancer agent that induces apoptosis. anticancer agent 46 exhibits cytotoxic effects in cancer cells and shows low toxicity to activated lymphocytes of human blood. | |||
T63489 | Anticancer agent 77 | ||
Anticancer agent 77 exhibits anticancer effects and can be used extensively in synthetic and medicinal chemistry studies. | |||
T63982 | Anticancer agent 50 | ||
Anticancer agent 50 (compound 6) is a potent modulator of the ABCB1 efflux pump with cytotoxic and anti-proliferative activity. anticancer agent 50 reduces the expression of cyclin D1 and induces p53 expression. anticanc... | |||
T61576 | Anticancer agent 83 | ||
Anticancer agent 83 is a potent anticancer agent, inhibits LOX IMVI cells growth with a GI 50 value of 0.15 mM. Anticancer agent 83 reduces mitochondrial membrane potential and induces DNA damage to induces leukemia cell... | |||
T61902 | Anticancer agent 69 | ||
Anticancer agent 69 (Compound 34) is an effective selective anticancer agent with selective inhibition on human prostate cancer cell line PC3 (IC50=26 nM). Anticancer agent 69 can increase ROS level and down-regulate EGF... | |||
T61673 | Anticancer agent 56 | ||
Anticancer agent 56 (compound 4d) is a powerful anti-cancer compound with favorable drug-like properties. It shows significant anticancer activity against multiple cancer cell lines, with an IC50 value of less than 3 μM.... | |||
T83095 | Anticancer agent 101 | ||
Anticancer Agent 101, a tetracaine derivative, exhibits anti-cancer activity [1]. | |||
T79247 | Anticancer agent 127 | IAP | |
Anticancer agent 127 (142D6), an IAP inhibitor, covalently binds to the BIR3 domains of XIAP, cIAP1, and cIAP2, with IC50 values of 12 nM, 14 nM, and 9 nM, respectively, demonstrating anticancer effects [1]. | |||
T83082 | Anticancer agent 168 | ||
Compound D16 (Anticancer agent 168) is an inhibitor of DNA2 that induces apoptosis and cell-cycle arrest predominantly in the S-phase. It demonstrates anticancer efficacy and can counteract chemotherapy resistance in can... | |||
T78941 | Anticancer agent 130 | Apoptosis | |
Anticancer agent 130 (compound 8d) significantly induces apoptosis in A549 cells [1]. | |||
T63830 | Anticancer agent 76 | ||
Anticancer agent 76 (Compound CT2-3) is an anti-cancer agent that significantly inhibits proliferation, induces cell cycle arrest, ROS production and apoptosis in human NSCLC cells. | |||
T78957 | Anticancer agent 105 | Apoptosis | |
Anticancer agent 105, a thienopyrimidine scaffold-based compound, exhibits selective toxicity towards melanoma and induces apoptosis. Additionally, it significantly inhibits metastatic nodules, including in a pulmonary m... | |||
T83079 | Anticancer agent 172 | ||
Anticancer agent 172 (8d) exhibits potent activity against cancer, achieving an IC50 value of 6.96 μM in HCT116 cells [1]. | |||
T79844 | Anticancer agent 143 | Phosphatase | |
Anticancer Agent 143 (Compound 369), a potent dual inhibitor targeting PTPN2 and PTP1B, exhibits IC50 values below 2.5 nM. It is employed in cancer research [1]. | |||
T83076 | Anticancer agent 93 | ||
Anticancer Agent 93, a 4-Hydroxycoumarin derivative, inhibits the invasion and migration of lung cancer cells through modulation of epithelial-mesenchymal transition (EMT) effector expression [1]. | |||
T79646 | Anticancer agent 153 | Apoptosis | |
Anticancer Agent 153 (Compound 3) promotes apoptosis through the generation of Reactive Oxygen Species (ROS) and elevates the loss of Mitochondrial Membrane Potential (MMP), effectively inhibiting cancer cell proliferati... | |||
T78742 | Anticancer agent 132 | Apoptosis | |
Compound Rh1 (Anticancer agent 132) acts as an inducer of apoptosis and autophagy, exhibiting both antitumor and antimetastatic activities. It also arrests the cell cycle and inhibits cell proliferation [1]. | |||
T79248 | Anticancer agent 128 | IAP | |
Anticancer agent 128 (compound 1) is an IAP inhibitor that covalently binds to the BIR3 domains of XIAP, cIAP1, and cIAP2, exhibiting IC50 values of 24.9 nM, 19.3 nM, and 10.3 nM, respectively [1]. | |||
T79465 | Anticancer agent 135 | Androgen Receptor | |
Anticancer agent 135 (compound 26h) acts as a potent androgen receptor (AR) antagonist, effectively blocking AR nuclear translocation and inhibiting AR/AR-V7 heterodimerization to suppress downstream gene transcription. ... | |||
T83087 | Anticancer agent 158 | ||
Anticancer agent 158 (compound 7c) demonstrates potent efficacy against various cancer cell lines, with IC50 values of 7.93 μM for HepG-2, 9.28 μM for MDA-MB-231, and 13.28 μM for HCT-116; however, it exhibits reduced po... | |||
T79843 | Anticancer agent 142 | Phosphatase | |
Compound 142 (also known as Compound 235) is a PTPN inhibitor with potential applications in cancer research [1]. | |||
T74521 | Anticancer agent 52 | ||
Anticancer agent 52 is a potent anticancer agent. Anticancer agent 52 shows in vitro cytotoxicity. Anticancer agent 52 induces apoptosis . Anticancer agent 52 shows antitumor effect. Anticancer agent 52 has the potential... | |||
T74767 | Anticancer agent 102 | ||
Anticancer agent 102 is a derivative of tetracaine. Anticancer agent 102 has anti-cancer activity. Anticancer agent 102 induces apoptosis [1] . | |||
T62601 | Anticancer agent 48 | ||
Anticancer agent 48 (compound 48) is a broad-spectrum anticancer agent with anti-proliferative activity. anticancer agent 48 inhibits microtubule protein polymerisation and has anti-tumour activity in vivo. anticancer ag... | |||
T62044 | Anticancer agent 71 | ||
Anticancer agent 71 (Compound 4b) is a potent anticancer agent. Anticancer agent 71 arrests cell cycle at G2/M phase. Anticancer agent 71 induces apoptosis through upregulating Bax, Ikb-α and cleaved PARP and downregulat... | |||
T61230 | Anticancer agent 74 | ||
Anticancer agent 74 exhibits moderate anticancer activity with lower selectivity and cytotoxicity compared to doxorubicin towards normal cells [1]. | |||
T61777 | Anticancer agent 42 | ||
Anticancer agent 42 (compound 10d) is an orally active, potent anticancer agent with demonstrated efficacy against MDA-MB-231 cells, exhibiting an IC50 of 0.07 μM. It exerts its anticancer activity through the activation... | |||
T60314 | Anticancer agent 38 | ||
Anticancer agent 38 (compound 19) is an aryl-urea compound, and is a potent anticancer agent. Anticancer agent 38 inhibits A431 cell growth with an IC 50 of 5.2 μg/mL [1]. | |||
T60998 | Anticancer agent 75 | ||
Anticancer agent 75 has good antiplasmodial activity. Anticancer agent 75 is a potent anticancer agent with cytotoxicity and selectivity in cancer cell lines. The cytotoxicity of Anticancer agent 75 to normal human kidne... | |||
T61973 | Anticancer agent 79 | ||
Anticancer agent 79 (compound 3d) is a anticancer compound with good anti-breast cancer activity. Anticancer agent 79 exhibits good cytotoxic activity in T47-D cells (IC50= 13.64 ± 0.26 μM). | |||
T63759 | Anticancer agent 44 | ||
Anticancer agent 44 is a potent and selective anticancer agent that induces apoptosis. anticancer agent 44 has cytotoxic activity in cancer cells and low toxicity in activated lymphocytes of human blood. | |||
T61750 | Anticancer agent 72 | ||
Anticancer agent 72 (compound 8c) effectively inhibits the K+ channel, displaying significant potential as an anticancer treatment. Additionally, it induces apoptosis, a programmed cell death process [1]. |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T83086 | Anticancer agent 160 | ||
Anticancer agent 160 (Compound 6), a natural product extracted from Parthenium hysterophorus, exhibits cytotoxicity against HCT-116 cells with an IC50 of 5.0 μM [1]. | |||
T83073 | Anticancer agent 96 | ||
Anticancer Agent 96 (Compound 4) exhibits cytotoxic activities against human cancer cells [1]. | |||
T83088 | Anticancer agent 156 | ||
Compound 156, also referred to as compound 11, is a potent miliusanes-based anticancer agent that demonstrates effective inhibition of human cancer cell growth and exhibits substantial cytotoxicity against gastric cancer... | |||
T83089 | Anticancer agent 149 | ||
Anticancer Agent 149 (compound 3), isolated from the rhizome of Dioscorea dioscorea (DM), demonstrates selective cytotoxicity against MCF-7 cells with an IC50 of 31.41 μM [1]. | |||
T9144 | Telekin | Others | |
Telekin, a eudesmane-type sesquiterpene lactone compound isolated from Chinese folk medicine Carpesium divaricatum, has been reported to strongly inhibit the proliferation of cancer cells | |||
TN1873 | Lirinidine | Others | |
(+)-Lirinidine has antioxidative activity, and it can significantly inhibit the proliferation of melanoma cells; it also shows potent inhibition of melanogenesis. Lirinidine exhibits significant inhibition of collagen, a... | |||
T21065 | Artemisitene | Others | |
Artemisitene is the oxidized form of Artemisinin and is an antimalarial agent. Artemisinin precursors are the important basic substances for biosynthesis of Artemisinin, including Artemisinin B, Artemisitene, Artemisini... | |||
TN6771 | Malabaricone B | Others | |
Malabaricone B is a Spice-derived phenolic, it induces mitochondrial damage in lung cancer cells via a p53-independent pathway. | |||
T10668 | Camalexin | Reactive Oxygen Species , ROS , Antibacterial , Antifungal | |
Camalexin is a phytoalexin isolated from Camelina sativa. It has antifungal, antibacterial, antiproliferative, and anticancer activities. Camalexin can induce ROS production. | |||
TN6739 | Angoline | 6-Methoxyldihydrochelerythrine | IL Receptor , STAT |
Angoline (6-Methoxyldihydrochelerythrine) hydrochloride is a potent and selective IL6/STAT3 signaling pathway inhibitor(IC50 : 11.56 μM). It inhibits STAT3 phosphorylation and its target gene expression, and inhibits can... | |||
TN1079 | Deoxyelephantopin | NF-κB | |
Deoxyelephantopin has anti-inflammatory, hepatoprotective, and wound healing activities; it also has antitumor activity.Deoxyelephantopin inhibits NF-κB, MAPK, PI3K/Akt, and β-catenin signaling | |||
TN7060 | Methyl oleanonate | PPAR | |
3-Oxoolean-12-en-28-oic acid methyl ester is a triterpenoid PPARγ agonist isolated from Pistacia with anticancer properties. | |||
T7052 | Gnetol | Tyrosinase , COX , HDAC , AChR | |
Gnetol competitivity inhibits butyrylcholinesterase (IC50: 1.3 uM). Gnetol has a strong inhibitory effect on murine tyrosinase activity. Gnetol significantly suppresses melanin biosynthesis in murine B16 melanoma cells. ... | |||
T2853 | Curcumol | (-)-Curcumol | Apoptosis , JAK |
Curcumol ((-)-Curcumol), a pure monomer isolated extracted from Rhizoma Curcumaeis, has antitumor activities. | |||
TN1712 | Gossypin | NF-κB , S6 Kinase | |
Gossypin has antidiabetic, antioxdiant, anticonvulsant, anti-allergic, antiinflammatory, antinociceptive, cytotoxic and antibacterial activities; it inhibits the NF-kappaB activation pathway, which may explain its role i... | |||
T7544 | Fucoidan | Others | |
Fucoidan is found in various species of brown seaweed and algae,with anticancer, antiviral, neuroprotective, immune-modulating. | |||
T11685 | Isolongifolene | (-)-Isolongifolene | Apoptosis , Others |
Isolongifolene ((-)-Isolongifolene) has antioxidant, anti-inflammatory, anticancer and neuroprotective properties. Isolongifolene is a tricyclic sesquiterpene isolated from Murraya koenigii. Isolongifolene attenuates Rot... | |||
T9715 | Aplidine | SARS-CoV , DNA/RNA Synthesis | |
Aplidine possesses antiviral activity against SARS-CoV-2(IC90 = 0.88 nM). Aplidine is a potent anti-cancer agent by targeting eukaryotic translation elongation factor 1 Alpha 2(EEF1A2, Kd = 80 nM). | |||
T3332 | Isosteviol | (-)-Isosteviol | IL Receptor , Potassium Channel , TNF , NF-κB , Reactive Oxygen Species , COX , Topoisomerase |
Isosteviol ((-)-Isosteviol), a common natural sweetener, belongs to tetracyclic diterpene glycosides. The pharmacology researches have suggested that stevioside and its hydrolysis products, steviol, isosteviol and stevio... | |||
T2731 | Usnic Acid | Usniacin | Antibacterial , Autophagy |
Usnic Acid (Usniacin) is an antimicrobial, antitumor and enzyme inhibiting agent shown to uncouple oxidative phosphorylation in mouse-liver mitochondria. Usnic acid induces necrosis in certain cells. | |||
T1134 | Clofoctol | Antibacterial , Antibiotic | |
Clofoctol is a bacteriostatic antibiotic with activity against Gram-positive bacteria, used in the treatment of upper and lower respiratory tract infections. | |||
T5613 | Squalane | Dodecahydrosqualene,Perhydrosqualene | Others |
Squalane (Perhydrosqualene) is a naturally occurring lipid in both plants and animals. It is usually used as a moisturizer and emollient in cosmetics manufacturing. | |||
TN1990 | Norathyriol | 芒果 | Akt , DNA/RNA Synthesis , AMPK , PPAR |
Norathyriol is a potent PTP1B inhibitor with good cell permeability and oral availability. | |||
TN1727 | Helichrysetin | Apoptosis , HIV Protease | |
Helichrysetin has mild anti-HIV-1 PR activity. Helichrysetin has great potentials for development as an anticancer agent, it has cytotoxic effect on four selected cancer cell lines, A549, MCF-7, Ca Ski, and HT-29. | |||
T7730 | Aminopterin | APGA,4-Aminofolic acid | Antifolate |
Aminopterin (4-Aminofolic acid) is a synthetic folic acid derivative whose metabolite is a competitive inhibitor of dihydrofolate reductase | |||
T3921 | Punicalagin | SARS-CoV , HBV | |
Punicalagin is a major ellagitannin found in pomegranates that is reported to produce antioxidant, anti-inflammatory, and anticancer effects. It has been shown to prevent high-fat diet-induced obesity-associated accumula... | |||
T6995 | Ochromycinone | STA 21,STA21,STA-21 | Antibacterial , STAT |
Ochromycinone (STA 21) is a selective STAT3 inhibitor. | |||
TN7059 | Deoxylimonin | NSC 314317,desoxylimonin | Others |
Deoxylimonin (NSC 314317) is a triterpenoid isolated from grapefruit seeds. | |||
T3912 | Saikosaponin B1 | Others | |
Saponin activator. Activates release of Prostaglandin E2 in vitro. Anti-inflammatory agent. Orally active. Active in vivo and in vitro. | |||
T2800 | L-Theanine | Apoptosis , Others | |
L-Theanine is a relaxing and nondietary amino acid found pretty much exclusively in teas from Camellia sinensis and is known to promote relaxation without sedation. | |||
T5S0055 | Chelidonine | Helidonine,Khelidonin,Stylophorin | Apoptosis , Others , Influenza Virus |
1. Chelidonine (Stylophorin) isolated from Chelidonium majus efficiently induced apoptosis in HeLa cells through possible alteration of p38-p53 and AKT/PI3 kinase signalling pathways. 2. Chelidonine is a promising model ... | |||
T0610 | Piceatannol | trans-Piceatannol,Astringenin | Apoptosis , Serine/threonin kinase , PKA , Syk , PKC , Autophagy |
Piceatannol (Astringenin) is an anti-inflammatory, immunomodulatory and antiproliferative agent. It inhibits p56lck and syk protein tyrosine kinases and inhibits NF-κB activation and gene expression of TNF-induced. It is... | |||
T2230 | Paeoniflorin | Peoniflorin | HSP , COX |
Paeoniflorin (Peoniflorin) is a herbal constituent extracted from the root of Paeonia albiflora Pall. | |||
TN1195 | 17-Hydroxy sprengerinin C | 17-羟基 SPRENGERININ C | BCL , Others , Caspase |
17-Hydroxy sprengerinin C is a glycoside compound isolated from rhizomes of Polygonatum sibiricum with stronger anticancer activities. 17-Hydroxy sprengerinin C reduces the expression of Blc-2 and pro-caspase3 and increa... | |||
T6431 | Levoleucovorin Calcium | Calcium Levofolinate,CL307782 | Others , Antifolate |
Levoleucovorin Calcium (CL307782), a calcium salt of the folinic acid, is used in cancer chemotherapy as an adjuvant. | |||
T6169 | Indirubin | Indigopurpurin,Indigo red,NSC 105327,Couroupitine B | Apoptosis , Raf , GSK-3 , CDK |
Indirubin (Couroupitine B) is a potent cyclin-dependent kinases and GSK-3β inhibitor with IC50 of about 5 uM and 0.6 uM. | |||
T4S0094 | Hydroxygenkwanin | Luteolin 7-methylether,7-O-Methylluteolin | Antioxidant |
1. Hydroxygenkwanin (Luteolin 7-methylether) possesses significant the antioxidative activity . 2. Hydroxygenkwanin has cytotoxicity, may be an effective natural product to treat glioma, and the combination of Apigenin a... | |||
T1011 | Itraconazole | R51211 | P450 , Hedgehog/Smoothened , Antibiotic , Autophagy , Antifungal |
Itraconazole (R51211) is a triazole antifungal agent that inhibits cytochrome P-450-dependent enzymes required for ERGOSTEROL synthesis. | |||
T1611 | Isotretinoin | 13-cis-Retinoic acid | Retinoid Receptor , Endogenous Metabolite , Autophagy |
Isotretinoin (13-cis-Retinoic acid) binds to and activates nuclear retinoic acid receptors (RARs); activated RARs serve as transcription factors that promote cell differentiation and apoptosis. Isotretinoin is a naturall... | |||
T2763 | Panaxadiol | 20(R)-Panaxadiol | Others , HIF/HIF Prolyl-Hydroxylase |
Panaxadiol (20(R)-Panaxadiol) is a novel antitumor agent extracted from the Chinese medical herb Panax ginseng. | |||
T2S0961 | Chalcone | benzylideneacetophenone,phenyl styryl ketone,Cinnamophenone,benzalacetophenone,β-phenylacrylophenone | EGFR , Antibacterial |
Chalcone (Cinnamophenone) is an aromatic ketone that forms the central core for a variety of important biological compounds, which are known collectively as chalcones. | |||
T7786 | Tryptanthrin | DNA gyrase | |
Tryptanthrin is a natural DNA gyrase inhibitor. | |||
T5668 | Triacetylresveratrol | Acetyl-trans-resveratrol | BCL , NF-κB , STAT |
Triacetylresveratrol (Acetyl-trans-resveratrol) has anti-cancer activity,it inhibits the phosphorylation of STAT3 and NFκB, down-regulates Mcl-1, and up-regulates Bim and Puma in pancreatic cancer cells. | |||
T4S21320 | ISOGINKGETIN | 4',4'''-Dimethylamentoflavone | MMP , Others |
1. ISOGINKGETIN (4',4'''-Dimethylamentoflavone), a compound derived from the leaves of Ginkgo biloba, to up-regulate adiponectin secretion with potency comparable to that of rosiglitazone, a known modulator of adiponecti... | |||
T2902 | Costunolide | Costus lactone,NSC 106404,Costunolid,(+)-Costunolide | Apoptosis , Endogenous Metabolite , Telomerase |
Costunolide (Costus lactone) has anti-inflammatory and anti-oxidant properties and mediates apoptosis. | |||
T0687 | Simvastatin | MK-0733,MK 733 | Apoptosis , Mitophagy , Ferroptosis , HMG-CoA Reductase , Autophagy |
Simvastatin (MK 733) is a HMG-CoA Reductase Inhibitor. The mechanism of action of simvastatin is as a Hydroxymethylglutaryl-CoA Reductase Inhibitor. | |||
T3604 | Sodium dichloroacetate | Sodium Dichloroacetate,DCA,BCA,bichloroacetic acid,Sodium dichloroacetate (DCA) | Apoptosis , Dehydrogenase , Reactive Oxygen Species , PDK |
Sodium dichloroacetate (BCA) , a specific inhibitor of pyruvate dehydrogenase kinase (PDK) with IC50 values of 183 and 80 μM for PDK2 and PDK4 respectively, has been shown to derepress a mitochondrial potassium-ion chann... | |||
T4036 | Solasodine | Solancarpidine,Purapuridine,Solasodin | Apoptosis , Others , E1/E2/E3 Enzyme , Antifungal |
Solasodine (Purapuridine)(Purapuridine) is a poisonous alkaloid chemical compound that occurs in plants of the Solanaceae family. Solasodine showed selective cytotoxicity against cervical cancer cell line (HeLa) and huma... | |||
T2755 | Rhoifolin | Apigenin-7-O-rhamnoglucoside,Apigenin 7-O-neohesperidoside,Rhoifoloside | Others , p38 MAPK , NF-κB , transporter , IGF-1R , Autophagy |
Rhoifolin (Apigenin 7-O-neohesperidoside) is extracted from Turpinia arguya Seem dried leaves. | |||
T7064 | Valproic Acid | Sodium valproate,2-Propylpentanoic Acid,VPA,Depakine,2-Propylvaleric Acid | Mitophagy , Gamma-secretase , HIV Protease , GABA Receptor , Sodium Channel , HDAC , Autophagy |
Valproic Acid (2-Propylpentanoic Acid) is a branched chain fatty acid which potentially enhances central GABAergic neurotransmission and inhibits Na+ channels. Currently, the various molecular mechanisms of action of Val... | |||
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Cat No. | Product Name | Species | Expression System |
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TMPY-05033 | 5T4/TPBG Protein, Human, Recombinant (aa 60-345, His) | Human | HEK293 |
Trophoblast glycoprotein (TPBG), also known as 5T4, is the therapeutic target of several anticancer agents currently in clinical development, largely due to its high expression in tumors and low expression in normal adul... | |||
TMPY-04644 | PDGFB Protein, Human, Recombinant (His) | Human | Yeast |
Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionalit... | |||
TMPY-06191 | 5T4/TPBG Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Trophoblast glycoprotein (TPBG), also known as 5T4, is the therapeutic target of several anticancer agents currently in clinical development, largely due to its high expression in tumors and low expression in normal adul... | |||
TMPY-06214 | 5T4/TPBG Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
Trophoblast glycoprotein (TPBG), also known as 5T4, is the therapeutic target of several anticancer agents currently in clinical development, largely due to its high expression in tumors and low expression in normal adul... | |||
TMPY-06317 | 5T4/TPBG Protein, Human, Recombinant (aa 1-355, His) | Human | HEK293 |
Trophoblast glycoprotein (TPBG), also known as 5T4, is the therapeutic target of several anticancer agents currently in clinical development, largely due to its high expression in tumors and low expression in normal adul... | |||
TMPK-01310 | Syndecan-1 Protein, Rabbit, Recombinant (His) | Rabbit | HEK293 |
CD138 (syndecan-1, Sdc-1) is a member of the syndecan family that comprises heparan sulfate proteoglycans. CD138 is significant for cell-cell and cell-matrix interactions.CD138 plays a crucial role in carcinogenesis and ... | |||
TMPK-00721 | CX3CL1/Fractalkine Protein, Mouse, Recombinant (His & Avi), Biotinylated | Mouse | HEK293 |
Fractalkine/CX3C chemokine ligand 1 (CX3CL1) is a chemokine involved in the anticancer function of lymphocytes-mainly NK cells, T cells and dendritic cells. Its increased levels in tumors improve the prognosis for cancer... | |||
TMPY-02395 | PDGFB Protein, Cynomolgus, Recombinant (mFc) | Cynomolgus | HEK293 |
Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionalit... | |||
TMPY-05077 | PDGFB Protein, Rhesus, Recombinant (His) | Rhesus | Yeast |
Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionalit... | |||
TMPY-04877 | PDGFB Protein, Mouse, Recombinant (His) | Mouse | Yeast |
Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionalit... | |||
TMPY-05076 | PDGFB Protein, Canine, Recombinant (His) | Canine | Yeast |
Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionalit... | |||
TMPK-00710 | Claudin-4 Protein-VLP, Human, Recombinant | Human | HEK293 |
Claudin-4 (CLDN4) is a key component of tight junctions (TJs) in epithelial cells. CLDN4 is overexpressed in many epithelial malignancies and correlates with cancer progression. Changes in CLDN4 expression have been asso... | |||
TMPK-00060 | IL-17B Protein, Mouse, Recombinant (His) | Mouse | E. coli |
IL-17A, the prototypic member of the IL-17 family, several experimental findings strongly support the role of the IL-17B/IL-17 receptor B (IL-17RB) pathway in tumorigenesis and resistance to anticancer therapies. IL-17B/... | |||
TMPJ-00247 | METAP1 Protein, Human, Recombinant | Human | E. coli |
Methionine Aminopeptidase 1 is a member of the M24 family of metalloproteases. METAP1 plays an important role in G(2)/M phase regulation of the cell cycle and may serve as a promising target for the discovery and develop... | |||
TMPY-00324 | METAP1 Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
Processing of the N-terminal initiator methionine or formylated methionine is an essential cellular process conserved from prokaryotes to eukaryotes. The proteolytic removal of N-terminal methionine from nascent peptides... | |||
TMPY-00883 | METAP1 Protein, Human, Recombinant (hFc) | Human | HEK293 |
Processing of the N-terminal initiator methionine or formylated methionine is an essential cellular process conserved from prokaryotes to eukaryotes. The proteolytic removal of N-terminal methionine from nascent peptides... | |||
TMPY-01865 | BLMH Protein, Mouse, Recombinant (His) | Mouse | E. coli |
The papain superfamily member bleomycin hydrolase (BLMH) is a cytoplasmic cysteine peptidase that is highly conserved through evolution. The only known activity of the enzyme is metabolic inactivation of the glycopeptide... | |||
TMPY-04143 | Chemerin/RARRES2 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
Retinoic acid receptor responder protein 2 (RARRES2) is a small secreted protein involved in multiple cancers, including adrenocortical carcinoma (ACC). Serum RARRES2 may be used as a novel prognostic marker for ACC. Ret... | |||
TMPY-00367 | Chemerin/RARRES2 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Retinoic acid receptor responder protein 2 (RARRES2) is a small secreted protein involved in multiple cancers, including adrenocortical carcinoma (ACC). Serum RARRES2 may be used as a novel prognostic marker for ACC. Ret... | |||
TMPY-02072 | HSF1 Protein, Human, Recombinant (His) | Human | E. coli |
Heat shock factor protein 1, also known as heat shock transcription factor 1, HSF1, and HSTF1, is a cytoplasm and nucleus protein that belongs to the HSF family. HSF1 is the major transcription factor of HSPs (heat shock... | |||
TMPY-02076 | PIN1 Protein, Human, Recombinant (His) | Human | E. coli |
Peptidyl-prolyl cis-trans isomerase Pin1, also known as Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, Rotamase Pin1 and PIN1, peptidyl-prolyl cis/trans isomerase (PPIase), is a nucleus protein. PIN1 is a peptid... | |||
TMPY-02114 | PIN1 Protein, Human, Recombinant | Human | E. coli |
Peptidyl-prolyl cis-trans isomerase Pin1, also known as Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, Rotamase Pin1 and PIN1, peptidyl-prolyl cis/trans isomerase (PPIase), is a nucleus protein. PIN1 is a peptid... |
Cat No. | Product Name | ||
---|---|---|---|
L2180 | Anti-Cancer Compound Library Plus | 1468 compounds | |
Well-chosen 1468 anti-tumor compounds with unique structures; | |||
L2150 | Anti-Cancer Drug Library | 3159 compounds | |
A unique collection of 3159 anticancer drugs for high throughput screening (HTS) and high content screening (HCS); | |||
L2100 | Anti-Cancer Compound Library | 7360 compounds | |
A unique collection of 7360 compounds with anti-cancer activity for high throughput screening (HTS) and high content screening (HCS); | |||
L2160 | Anti-Cancer Active Compound Library | 3250 compounds | |
A unique collection of 3250 compounds with known anti-cancer activity for high throughput screening (HTS) and high content screening (HCS); | |||
L2110 | Anti-Cancer Approved Drug Library | 1825 compounds | |
A unique collection of 1825 approved anti-cancer drugs for high throughput screening (HTS) and high content screening (HCS); | |||
L2120 | Anti-Cancer Clinical Compound Library | 2614 compounds | |
A unique collection of 2614 anti-cancer compounds for high throughput screening (HTS) and high content screening (HCS); | |||
L2130 | Anti-Cancer Metabolism Compound Library | 1280 compounds | |
A unique collection of 1280 cancer cellular metabolism related compounds for cancer research and high throughput screening (HTS) and high content screening (HCS); | |||
L2151 | Chemotherapy Drug Library | 51 compounds | |
51 Chemotherapeutic drugs that can be used for high-throughput and high-content screening. | |||
L1110 | Microtubule-Targeted Compound Library | 155 compounds | |
A unique collection of 155 microtubule-targeted compounds can be used in HTS and HCS; | |||
L6110 | Alkaloid Natural Product Library | 468 compounds | |
A unique collection of 468 natural alkaloids can be used for high throughput and high content screening; | |||
NY1000 | Natural Product Derivatives Library | 4000 compounds | |
The library consists of more than 4,000 members belonging 22 scaffolds (average 180 compounds per scaffold). | |||
L6100 | Polyphenolic Natural Product Library | 640 compounds | |
A unique collection of 640 natural polyphenolic compounds for high throughput screening (HTS) and high content screening (HCS); | |||
L6130 | Terpene Natural Product Library | 522 compounds | |
A unique collection of 522 natural terpenes and terpenoids can be used for high throughput and high content screening; | |||
L6900 | Rare Natural Product Library | 180 compounds | |
A unique collection of 180 rare natural products, which can be used for high throughput screening (HTS) and high content screening (HCS); | |||
L1100 | Protease Inhibitor Library | 344 compounds | |
A unique collection of 344 protease and proteasome inhibitors for research in chemical genomics, and drug screening; | |||
L6700 | Anti-Tumor Natural Product Library | 1800 compounds | |
A unique collection of 1800 natural products with known anti-cancer activity for high throughput screening (HTS) and high content screening (HCS); | |||
L5100 | Fluorochemical Library | 583 compounds | |
A unique collection of 583 fluorochemicals that can be used for high through-put screening (HTS) and high content screening (HCS); | |||
L6020 | Selectable Natural Product Library | 16627 compounds | |
A unique collection of 16627 pure natural products with diverse structures and sources covering various plant, animal, and microbe species; | |||
L6820 | Tobacco Monomer Library | 750 compounds | |
A unique collection of 750 tobacco monomer compounds for high throughput screening and high content screening; |