m 2

M2 ion channel blocker ,Antiviral agent, is capable of inhibiting and blocking the activity of M2 ion channel.

Aflatoxin M2 is a major metabolite of Aflatoxin B1 and is a mycotoxin produced by the fungi Aspergillus flavus and Aspergillus parasiticus.

Dacomitinib metabolite M2 is also known as Dacomitinib cysteine conjugate. Dacomitinib inhibits both the wild-type (WT) EGFR and EGFR T790M.

Gomisin M2 is an anti-HIV agent.

Compound 43, known as M1/M2/M4 muscarinic agonist 2, functions as an mAChR M1/M2/M4 agonist with respective EC50 values of 30 nM, 200 nM, and 6.2 nM.

Antibiotic MA 144M2 is an anthracycline glycoside that inhibits the growth of gram-positive bacteria, e.g. Staphyococcus aureaus, Bacillus subtilis and Sarcina lutea, and inhibits the growth of animal tumors such as leukemia L 1210, P 388 and sarcoma 180. It's produced by fermentation of MA 144-producing strains of streptomyces and by the chemical or enzymatic conversion of aclacinomycin A or cinerubin A.

Compound 42, also known as M1/M2/M4 muscarinic agonist 1, is a muscarinic M4/M1/M2 agonist exhibiting EC50 values of 6.5, 26, and 210 nM for M4, M1, and M2 respectively. This compound is utilized in research focused on mental disorders, including schizophrenia and delusion [1].

Muscarinic agonist 3 (compound 45) is a muscarinic mAChR M1/M2/M4 agonist with EC50 values of 3.2 nM, 32 nM, and 1.7 nM, respectively [1].

U-[13C17]-Aflatoxin M2 in Acetonitrile (Standard) is a fully 13C isotope-labeled aflatoxin M2 solution that can be used as an analytical standard for the determination of aflatoxin M2 in samples.

Neoenactin M2 exhibits strong antifungal activity against yeasts and filamentous fungi.

M2 Peptide is a targeting peptide specific to M2-like tumor-associated macrophages (TAMs). It serves as a carrier for drugs or small interfering RNA (siRNA) to facilitate the repolarization of M2-like macrophages to M1-like macrophages. This shift alters the immunosuppressive state within the tumor microenvironment, enhancing the antitumor immune response. M2 Peptide is used in research to study its effects on macrophage polarization and the implications of this polarization on tumor growth and metastasis.

SCH 57790 is a novel and selective muscarinic M(2) receptor antagonist that releases acetylcholine and enhances cognition in experimental animals for the treatment of Alzheimer's disease.

Amantadine hydrochloride (CI-719) is an antiviral that is used in the prophylactic or symptomatic treatment of influenza A and Parkinson disease.

Amantadine (1-Aminoadamantane) is an antiviral, is a weak antagonist of the NMDA-type glutamate receptor, increases dopamine release, and blocks dopamine reuptake.

M2N12 is a potent and highly selective inhibitor of cell division cycle 25C protein phosphatase (Cdc25C, IC50 = 0.09 μM) and also exhibits anti-tumor activity. Additionally, M2N12 shows promising activity against Cdc25A (IC50 = 0.53 μM) and Cdc25B (IC50 = 1.39 μM).

KGP94 is an inhibitor of cysteine protease Cathepsin L(CTSL).

Regorafénib N-oxyde M2 is an active metabolite of Regorafenib, a multi-target inhibitor for VEGFR1/2/3, PDGFRβ, RET, Kit, and Raf-1 (IC50s: 13/4.2/46, 1.5, 22, 7, and 2.5 nM).

LSN2839567 (Abemaciclib metabolite M2) is the active metabolite of Abemaciclib, a potent CDK4 and CDK6 inhibitor (IC50s: 1-3 nM) with anticancer activity.LSN2839567 inhibits CDK9.LSN2839567 inhibits cell growth and cell cycle progression in a concentration-dependent manner. cell growth and cell cycle progression in a concentration-dependent manner and can be used to study breast and lung cancer.

m-(2-Phenoxyethoxy)phenol is a biaoctive chemical.

Phenol, m-(2-(methylamino)ethyl)-, hydrochloride is a biaoctive chemical.

Pimethixene (Calmixen) is a highly potent 5-HT1A, 5-HT2A, 5-HT2B, 5-HT2C, histamine H1, dopamine D2 and D4.4 as well as muscarinic M1 and M2 receptors antagonist(pKis of 7.63, 10.22, 10.44, 8.42, 10.14, 8.19, 7.54, 8.61 and 9.38, respectively).

Pimethixene maleate (Pimetixene maleate) is a potent 5-HT2B receptor antagonist with sedative and antitussive activity.Pimethixene maleate inhibits 5-HT1A, 5-HT2A, 5-HT2B, 5-HT2C, histamine H1, dopamine D2 and D4.4 as well as muscarinic M1 and M2, and can be used in studies of dry and irritant cough in children. irritant cough in children.

Otenzepad (AF-DX 116) is a selective M2 mAChR antagonist with IC50 values of 386 nM in rat heart and 640 nM in rabbit peripheral lung.

M2e, human, a vaccine candidate for human influenza A, encompasses the 23 extracellular residues of M2 (the third integral membrane protein of influenza A) and exhibits remarkable conservation across all strains, highlighting its potential as a broadly protective option.