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Anti-TTR/Prealbumin Antibody (2M425)
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Catalog No. TMAB-13887
Anti-TTR/Prealbumin Antibody (2M425) is a Mouse antibody targeting TTR/Prealbumin. Anti-TTR/Prealbumin Antibody (2M425) can be used in IHC-P,IHC-Fr,IF.
Anti-TTR/Prealbumin Antibody (2M425)
Anti-TTR/Prealbumin Antibody (2M425)
Copy Product Info😃Good
Catalog No. TMAB-13887
Anti-TTR/Prealbumin Antibody (2M425) is a Mouse antibody targeting TTR/Prealbumin. Anti-TTR/Prealbumin Antibody (2M425) can be used in IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 200 μg | $1,057 | 7-10 days | 7-10 days | |
| 50 μL | $223 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-TTR/Prealbumin Antibody (2M425) is a Mouse antibody targeting TTR/Prealbumin. Anti-TTR/Prealbumin Antibody (2M425) can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Clone | 2M425 |
| Reactivity | Human |
| Verified Activity | 1. Paraformaldehyde-fixed, paraffin embedded (Human pancreatic cancer); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (TTR/Prealbumin) Monoclonal Antibody, Unconjugated (ascites of TMAB-13887-6B11) at 1: 2000 overnight at 4°C, followed by a conjugated secondary for 20 minutes and DAB staining. 2. Paraformaldehyde-fixed, paraffin embedded (Human liver carcinoma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (TTR) Monoclonal Antibody, Unconjugated (TMAB-13887) at 1:400 overnight at 4°C, followed by operating according to SP Kit (Mouse) instructions and DAB staining. |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Subcellular Localization | Secreted. Cytoplasm. |
| Tissue Specificity | Detected in serum and cerebrospinal fluid (at protein level). Highly expressed in choroid plexus epithelial cells. Detected in retina pigment epithelium and liver. |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Protein G purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | This gene encodes transthyretin, one of the three prealbumins including alpha-1-antitrypsin, transthyretin and orosomucoid. Transthyretin is a carrier protein; it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported; most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart, and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, carpal tunnel syndrome, etc. [provided by RefSeq] |
| Immunogen | Recombinant Protein: human TTR Protein |
| Antigen Species | Human |
| Gene Name | TTR |
| Gene ID | |
| Protein Name | Transthyretin |
| Function | Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain. |
| Molecular Weight | Theoretical: 14 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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