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Anti-GM2A Antibody (4Z337)
😃Good
Catalog No. TMAY-02554
Alias SAP-3, GM2-AP, GM2 ganglioside activator
Anti-GM2A Antibody (4Z337) is a Mouse antibody targeting GM2A. Anti-GM2A Antibody (4Z337) can be used in ELISA.
Anti-GM2A Antibody (4Z337)
Anti-GM2A Antibody (4Z337)
😃Good
Catalog No. TMAY-02554Alias SAP-3, GM2-AP, GM2 ganglioside activator
Anti-GM2A Antibody (4Z337) is a Mouse antibody targeting GM2A. Anti-GM2A Antibody (4Z337) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $198 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-GM2A Antibody (4Z337) is a Mouse antibody targeting GM2A. Anti-GM2A Antibody (4Z337) can be used in ELISA. |
| Alias | SAP-3, GM2-AP, GM2 ganglioside activator |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 4Z337 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 1:1000-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human GM2A (rh GM2A; TMPY-02765; AAA35907.1; Met1-Ile193). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | GM2A (GM2 ganglioside activator), is a lipid transfer protein which belongs to the ML domain family. GM2A can accommodate several single chain phospholipids and fatty acids. It also exhibits some calcium-independent phospholipase activity. GM2A binds gangliosides and stimulates ganglioside GM2 degradation. It stimulates only the breakdown of ganglioside GM2 and glycolipid GA2 by beta-hexosaminidase A. GM2A acts as a substrate specific co-factor for the lysosomal enzyme β-hexosaminidase A. β-hexosaminidase A, together with GM2 ganglioside activator, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. It extracts single GM2 molecules from membranes and presents them in soluble form to beta-hexosaminidase A for cleavage of N-acetyl-D-galactosamine and conversion to GM3. Defects in GM2A are the cause of GM2-gangliosidosis type AB (GM2GAB), also known as Tay-Sachs disease AB variant. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Human GM2A protein (TMPY-02765) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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