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Anti-p57 Kip2 Antibody (1M47)
😃Good
Catalog No. TMAB-09886
Anti-p57 Kip2 Antibody (1M47) is a Mouse antibody targeting p57 Kip2. Anti-p57 Kip2 Antibody (1M47) can be used in IHC-P,IHC-Fr,IF.
Anti-p57 Kip2 Antibody (1M47)
Anti-p57 Kip2 Antibody (1M47)
😃Good
Catalog No. TMAB-09886
Anti-p57 Kip2 Antibody (1M47) is a Mouse antibody targeting p57 Kip2. Anti-p57 Kip2 Antibody (1M47) can be used in IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-p57 Kip2 Antibody (1M47) is a Mouse antibody targeting p57 Kip2. Anti-p57 Kip2 Antibody (1M47) can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG2b, Kappa |
| Clone | 1M47 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Subcellular Localization | Nucleus. |
| Tissue Specificity | Expressed in the heart, brain, lung, skeletal muscle, kidney, pancreas and testis. Expressed in the eye. High levels are seen in the placenta while low levels are seen in the liver. |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | PBS (pH7.2), 0.03% Porcolin 300, containing stabilizing protein. |
| Concentration | 1mg/ml |
| Research Background | This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]. |
| Immunogen | KLH conjugated synthetic peptide: human p57 Kip2 |
| Antigen Species | Human |
| Gene Name | CDKN1C |
| Gene ID | |
| Protein Name | Cyclin-dependent kinase inhibitor 1C |
| Uniprot ID | |
| Function | Potent tight-binding inhibitor of several G1 cyclin/CDK complexes (cyclin E-CDK2, cyclin D2-CDK4, and cyclin A-CDK2) and, to lesser extent, of the mitotic cyclin B-CDC2. Negative regulator of cell proliferation. May play a role in maintenance of the non-proliferative state throughout life. |
| Molecular Weight | Theoretical: 35 kDa. |
Stability & Storage
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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