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Anti-Transglutaminase 2/TGM2 Antibody (3C930)
😃Good
Catalog No. TMAY-01634
Alias transglutaminase 2, TGC, TG2, HEL-S-45, G-α-h, GNAH, G-ALPHA-h
Anti-Transglutaminase 2/TGM2 Antibody (3C930) is a Rabbit antibody targeting Transglutaminase 2/TGM2. Anti-Transglutaminase 2/TGM2 Antibody (3C930) can be used in ELISA.
Anti-Transglutaminase 2/TGM2 Antibody (3C930)
Anti-Transglutaminase 2/TGM2 Antibody (3C930)
😃Good
Catalog No. TMAY-01634Alias transglutaminase 2, TGC, TG2, HEL-S-45, G-α-h, GNAH, G-ALPHA-h
Anti-Transglutaminase 2/TGM2 Antibody (3C930) is a Rabbit antibody targeting Transglutaminase 2/TGM2. Anti-Transglutaminase 2/TGM2 Antibody (3C930) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $269 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Rabbit Monoclonal Application: ELISA Reactivity: Human |
| Alias | transglutaminase 2, TGC, TG2, HEL-S-45, G-α-h, GNAH, G-ALPHA-h |
| Ig Type | Rabbit IgG |
| Clone | 3C930 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 1:5000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human TGM2 / Transglutaminase 2 (rh TGM2 / Transglutaminase 2; TMPY-01355; NP_004604.2; Met 1-Ala 687). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Protein-glutamine gamma-glutamyltransferase 2, also known as Tissue transglutaminase, Transglutaminase C, Transglutaminase-2, and TGM2, is a member of the transglutaminase superfamily. TGM2 plays a role in cell growth and survival through the anti-apoptosis signaling pathway. It is a calcium-dependent acyltransferase that also undergoes a GTP-binding/GTPase cycle even though it lacks any obvious sequence similarity with canonical GTP-binding (G) proteins. TGM2 is a multi-functional protein which catalyzes transamidation reactions or acts as a G-protein in intracellular signalling. As an enzyme which is responsible for the majority of transglutaminase (TG) activity in the brain, TGM2 is likely to play a modulatory role in nervous system development and has regulatory effect on neuronal cell death as well. Most importantly, numerous studies have presented data demonstrating that dysregulation of TGM2 may contribute to the pathogenesis of many neurodegenerative disorders, including Huntington's disease, Alzheimer's disease, Parkinson's disease and amyotrophic lateral sclerosis as well as nervous system injuries. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human TGM2 / Transglutaminase 2 protein (TMPY-01355) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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