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Anti-Transglutaminase 2/TGM2 Antibody (3C930)

🥰Excellent
Catalog No. TMAY-01634

Anti-Transglutaminase 2/TGM2 Antibody (3C930) is a Rabbit antibody targeting Transglutaminase 2/TGM2. Anti-Transglutaminase 2/TGM2 Antibody (3C930) can be used in ELISA.

Anti-Transglutaminase 2/TGM2 Antibody (3C930)

Anti-Transglutaminase 2/TGM2 Antibody (3C930)

🥰Excellent
Catalog No. TMAY-01634
Anti-Transglutaminase 2/TGM2 Antibody (3C930) is a Rabbit antibody targeting Transglutaminase 2/TGM2. Anti-Transglutaminase 2/TGM2 Antibody (3C930) can be used in ELISA.
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Product Introduction

Bioactivity
Description
Anti-Transglutaminase 2/TGM2 Antibody (3C930) is a Rabbit antibody targeting Transglutaminase 2/TGM2. Anti-Transglutaminase 2/TGM2 Antibody (3C930) can be used in ELISA.
Ig Type
Monoclonal Rabbit IgG
Clone
3C930
Reactivity
Human
Application
ELISA
Recommended Dose
ELISA: 1:5000-1:10000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Human TGM2 / Transglutaminase 2 (rh TGM2 / Transglutaminase 2; TMPY-01355; NP_004604.2; Met 1-Ala 687).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundProtein-glutamine gamma-glutamyltransferase 2, also known as Tissue transglutaminase, Transglutaminase C, Transglutaminase-2, and TGM2, is a member of the transglutaminase superfamily. TGM2 plays a role in cell growth and survival through the anti-apoptosis signaling pathway. It is a calcium-dependent acyltransferase that also undergoes a GTP-binding/GTPase cycle even though it lacks any obvious sequence similarity with canonical GTP-binding (G) proteins. TGM2 is a multi-functional protein which catalyzes transamidation reactions or acts as a G-protein in intracellular signalling. As an enzyme which is responsible for the majority of transglutaminase (TG) activity in the brain, TGM2 is likely to play a modulatory role in nervous system development and has regulatory effect on neuronal cell death as well. Most importantly, numerous studies have presented data demonstrating that dysregulation of TGM2 may contribute to the pathogenesis of many neurodegenerative disorders, including Huntington's disease, Alzheimer's disease, Parkinson's disease and amyotrophic lateral sclerosis as well as nervous system injuries.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Human TGM2 / Transglutaminase 2 protein (TMPY-01355)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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