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Anti-EPHB4 Monoclonal Antibody (1N998)
(Synonyms: TYRO11, MYK1, LMPHM7, HTK, HFASD, CMAVM2) Copy Product Info
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Synonyms: TYRO11, MYK1, LMPHM7, HTK, HFASD, CMAVM2
Catalog No. TMAT-0504 Copy Product Info
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Anti-EPHB4 Monoclonal Antibody (1N998) is a Mouse antibody targeting EPHB4. Anti-EPHB4 Monoclonal Antibody (1N998) can be used in IHC.
Anti-EPHB4 Monoclonal Antibody
(1N998)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Stability & Storage
| Description | Anti-EPHB4 Monoclonal Antibody (1N998) is a Mouse antibody targeting EPHB4. Anti-EPHB4 Monoclonal Antibody (1N998) can be used in IHC. |
| Synonyms | TYRO11, MYK1, LMPHM7, HTK, HFASD, CMAVM2 |
| Ig Type | IgG2a |
| Clone | 1N998 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IHC: 1/200-1/1000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | Ascitic fluid containing 0.03% sodium azide |
| Concentration | 1 mg/ml |
| Research Background | EPH receptor B4 (EphB4), with 987-amino acid protein (about 108kDa), belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. The Eph receptor tyrosine kinases and their ligands, the ephrins, regulate numerous biological processes in developing and adult tissues and have been implicated in cancer progression and in pathological forms of angiogenesis. EphB4 acts as a negative regulator of blood vessel branching and vascular network formation, switching the vascularization program from sprouting angiogenesis to circumferential vessel growth. EphB4 and its ligand ephrinB2 express in several kinds of tumor cells and correlate with tumorigenesis. EphB4 is thus a potential candidate as a predictor of disease outcome in several kinds of tumor and as target for novel therapy. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of EphB4 expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | EPHB4 |
| Gene ID | |
| Protein Name | Ephrin type-B receptor 4 |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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