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Anti-CD195 Monoclonal Antibody (8C419)
(Synonyms: IDDM22, CMKBR5, CKR-5, CKR5, CCR-5, CCR5, CC-CKR-5, CCCKR5) Copy Product Info
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Synonyms: IDDM22, CMKBR5, CKR-5, CKR5, CCR-5, CCR5, CC-CKR-5, CCCKR5
Catalog No. TMAT-0308 Copy Product Info
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Anti-CD195 Monoclonal Antibody (8C419) is a Mouse antibody targeting CD195. Anti-CD195 Monoclonal Antibody (8C419) can be used in WB,IHC,FCM.
Anti-CD195 Monoclonal Antibody
(8C419)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 20 µL | Inquiry | 7-10 days | 7-10 days | |
| 50 µL | Inquiry | 7-10 days | 7-10 days | |
| 100 µL | Inquiry | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Stability & Storage
| Description | Anti-CD195 Monoclonal Antibody (8C419) is a Mouse antibody targeting CD195. Anti-CD195 Monoclonal Antibody (8C419) can be used in WB,IHC,FCM. |
| Synonyms | IDDM22, CMKBR5, CKR-5, CKR5, CCR-5, CCR5, CC-CKR-5, CCCKR5 |
| Ig Type | IgG1 |
| Clone | 8C419 |
| Reactivity | Human,Rat |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IHC: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/ml |
| Research Background | This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. An allelic polymorphism in this gene results in both functional and non-functional alleles; the reference genome represents the functional allele. Two transcript variants encoding the same protein have been found for this gene. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human CD195 (AA: extra mix) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | CCR5 |
| Gene ID | |
| Protein Name | C-C chemokine receptor type 5 |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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