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Anti-TXNL4B Antibody (5F871)
😃Good
Catalog No. TMAY-02591
Alias thioredoxin-like 4B, DLP, Dim2
Anti-TXNL4B Antibody (5F871) is a Rabbit antibody targeting TXNL4B. Anti-TXNL4B Antibody (5F871) can be used in ELISA.
Anti-TXNL4B Antibody (5F871)
Anti-TXNL4B Antibody (5F871)
😃Good
Catalog No. TMAY-02591Alias thioredoxin-like 4B, DLP, Dim2
Anti-TXNL4B Antibody (5F871) is a Rabbit antibody targeting TXNL4B. Anti-TXNL4B Antibody (5F871) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $268 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Rabbit Monoclonal Application: ELISA Reactivity: Human |
| Alias | thioredoxin-like 4B, DLP, Dim2 |
| Ig Type | Rabbit IgG |
| Clone | 5F871 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 1:5000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human Dim2 / TXNL4B (rh Dim2 / TXNL4B; TMPY-02723; Q9NX01; Met1-Ile149). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Dim2, also known as TXNL4B, is a member of the DIM1 family. The Dim protein family is composed of two classes, Dim1and Dim2, which share a common thioredoxin-like fold. They were originally identified for their role in cell cycle progression and have been found to interact with Prp6, an essential component of the spliceosome, which forms the bridge of U4/U6.U5-tri-snRNP. Despite their biological and structural similarities, Dim1 and Dim2 proteins differ in many aspects. Dim1 bears distinctive structural motifs responsible for its interaction with other spliceosome components. Dim2 forms homodimers and contains specific domains required for its interactions with partners. This originality suggests that although both proteins are involved in pre-mRNA splicing, they are likely to be involved in different biological pathways. Dim2 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 185 amino acids and having a molecular mass of 21.1kDa. It is fused to a 36 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Dim2 has a vital role in pro-mRNA splicing. Dim2 is required in cell cycle progression for S/G2 transition and interacts with PRPF6 subunit of the spliceosome. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human Dim2 / TXNL4B protein (TMPY-02723) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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