f 2

MC-1-F2 is a direct FOXC2 inhibitor with anticancer activity, inhibits cancer stem cell (CSC) characteristics, and reduces the invasive ability of castration-resistant prostate cancer (CRPC) cell lines. MC-1-F2 can be used to study prostate cancer.

Labdane F2 is an antagonist of thromboxane B2 and leukotriene B4 isolated from the Spanish herb Sideritis javalambrensis.

Ginsenoside F2 has antiproliferative activity against breast cancer stem cells (CSCs). It induces apoptosis in breast CSCs by activating the intrinsic apoptotic pathway and mitochondrial dysfunction.

Icariside F2 shows modest α-glucosidase inhibitory (4.60±1.74% to 11.97±3.30%) and antioxidant activities. It also displays potent NF-κB inhibitory effects, with the IC50 value of 16.25 ± 2.19 uM.

cis-4-Br-2,5-F2-PCPA (S1024) inhibits LSD1 and LSD2 with Ki values of 94 nM and 8.4 μM, respectively. It inhibits LSD1 cell proliferation and increases dimethylated histone H3 at K4 (H3K4) in CCRF-CEM cells, particularly where there is aberrant expression of LSD1 in cancer stem cells [1].

Ginsenoside F2 (Standard) is a reference standard for research and analysis in studies involving Ginsenoside F2. Ginsenoside F2 has antiproliferative activity against breast cancer stem cells (CSCs). It induces apoptosis in breast CSCs by activating the intrinsic apoptotic pathway and mitochondrial dysfunction.

TC-F 2 is a FAAH inhibitor.

2-O-β-D-Glucopyranosylcucurbitacin F 25-acetate, a cucurbitacin glucoside, can be isolated from the polar fractions of the MeOH extract of Cigarrilla mexicana [1].

5'-DMT-5-F-2'-dU Phosphoramidite is a nucleoside phosphoramidite analog employed in oligonucleotide synthesis. It plays a crucial role in developing therapeutic oligonucleotides, which are used in crafting drugs for cancer treatment.

19(R)-Hydroxylated prostaglandins (PGs) are present at µg/ml concentrations in the semen of some mammalian species, notably primates, with the majority being from the PGE series and featuring a 15(S),19(R) hydroxyl stereochemistry. These compounds are also observed in marsupials' seminal plasma, where F-type 1 and 2-series compounds are predominant. The 15(R)-hydroxy epimer represents the inverse or "unnatural" isomer at C-15 for these 19-hydroxylated PGs. Although the biological function of 19(R)-hydroxylated PGs remains unclear, 19(R)-hydroxylation in the F-series leads to a notable reduction in receptor-mediated biological activity in certain assays.

Prostaglandin F2α dimethyl amine, a Prostaglandin F2α derivative, acts as an antagonist for the Prostaglandin F receptor (FP) [1]. It blocks the cardiovascular responses induced by orexin and Arachidonic acid [2].

Goshonoside F2 is a useful organic compound for research related to life sciences. The catalog number is T123946 and the CAS number is 90851-25-5.

Glycoside L-F2 is a useful organic compound for research related to life sciences and the catalog number is T125221.

Anemarrhenasaponin A2 (Schidigerasaponin F2) is a steroidal saponin isolated from the rhizomes of Anemarrhena asphodeloides. Anemarrhenasaponin A2 has been shown to inhibit ADP-induced platelet aggregation, suggesting its potential role in modulating thrombotic pathways and contributing to cardiovascular research.

XRK3F2 is an inhibitor of the p62-ZZ domain, blunts MM-induced Runx2 suppression in vitro, and induces new bone formation and remodeling in the presence of tumor in vivo.

17-Phenyl trinor prostaglandin F2α glycinamide methyl ester is a derivative of Bimatoprost and functions as a prostaglandin analogue. This compound acts as an agonist for the human prostaglandin FP receptor. It exhibits ocular hypotensive effects and is utilized in research related to ocular hypertension and glaucoma.

16-Phenyl tetranor Prostaglandin F2α (16-Phenyl tetranor PGF2α) is a metabolically stable analogue of PGF2α. Compared to PGF2α, 16-Phenyl tetranor PGF2α exhibits reduced affinity (8.7%) for the FP receptor on ovine luteal cells.

20-ethyl Prostaglandin F2α (ICI 74205; 20-ethyl PGF2α) is an analog of PGF2α and is a metabolite of arachidonic acid.

A2G2F2 glycan [A2G2F2(a1-3) glycan] is a symmetrical N-glycan containing two Lewis X epitopes, and is a type of Lewis X polysaccharide. SLeX serves as a ligand for the cell adhesion molecule E-selectin, which is specifically expressed at sites of inflammation. Designing conjugates of SLeX-polysaccharides can facilitate targeted drug delivery to inflammatory lesions.

17-Phenoxy trinor prostaglandin F2α isopropyl ester is a PGF2α analog. PGF2α acts as an orally active agonist of the PGF receptor (FP receptor). It plays a crucial role during childbirth.

8-iso Prostaglandin F2α ethanolamide (iPF2α-III ethanolamide; 8-Isoprostane ethanolamide; 8-iso PGF2α ethanolamide) is a derivative of isoprostane ethanolamide produced through the non-enzymatic free radical oxidation of arachidonoyl ethanolamide (AEA). It is commonly used as a biomarker for oxidative stress, helping to distinguish non-enzymatic breakdown products from enzyme-mediated prostamides generated via pathways such as COX-2.

11-deoxy-PGF2a is a thromboxane A2 receptor agonist that partially alleviates crowding in Lpar3(−/−) female embryos and induces smooth muscle contraction in the aorta, vena cava, and trachea.

KC7F2 is a potent HIF-1 pathway inhibitor with potential anti-cancer activity.

Bimatoprost is the Allergan trade name for 17-phenyl trinor prostaglandin F2α ethyl amide (17-phenyl trinor PGF2α ethyl amide), an F-series PG analog which has been approved for use as an ocular hypotensive drug. Oxidation of the C-15 hydroxyl group produces 15-keto-17-phenyl trinor PGF2α ethyl amide. 15-keto-17-phenyl trinor PGF2α ethyl amide is a potential metabolite of 17-phenyl trinor PGF2α ethyl amide when 17-phenyl trinor PGF2α ethyl amide is administered to intact animals. No pharmacological studies on 15-keto-17-phenyl trinor PGF2α ethyl amide have been reported.