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Utomilumab (Synonyms: PF-2566, PF 05082566)

Catalog No. T76705 Copy Product Info
Purity: 95%
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Utomilumab (PF 05082566) is a humanized IgG2 antibody that targets the T-cell co-stimulatory receptor 4-1BB/CD137 and acts as a 4-1BB/CD137 agonist. It exhibits antitumor activity and may be used in the study of patients with advanced malignancies.

Utomilumab

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Catalog No. T76705
Synonyms PF-2566, PF 05082566

Utomilumab (PF 05082566) is a humanized IgG2 antibody that targets the T-cell co-stimulatory receptor 4-1BB/CD137 and acts as a 4-1BB/CD137 agonist. It exhibits antitumor activity and may be used in the study of patients with advanced malignancies.

Utomilumab
Cas No. 1417318-27-4
Pack SizePriceUSA StockGlobal StockQuantity
1 mg$297In StockIn Stock
5 mg$747-In Stock
10 mg$1,180-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:95.1% (SDS-PAGE); 98.5% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Utomilumab (PF 05082566) is a humanized IgG2 antibody that targets the T-cell co-stimulatory receptor 4-1BB/CD137 and acts as a 4-1BB/CD137 agonist. It exhibits antitumor activity and may be used in the study of patients with advanced malignancies.
SynonymsPF-2566, PF 05082566
Reactivity
Human
Verified Activity
Immobilized Human 4-1BB/CD137/TNFRSF9 Protein (His) (TMPY-01743) at 1 μg/mL (100 μL/well) can bind Utomilumab. The EC50 is 2.85 ng/mL.
verifiedActivity
Application
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Gene ID
Uniprot ID
TargetTNFRSF9/4-1BB/CD137
Chemical Properties
Molecular Weight142.77 kDa
Cas No.1417318-27-4
Antibody Information
IsotypeIgG2SA
Storage & Solubility Information
Storagestore at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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