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Synonyms: RBP3, RBBP3, RBAP1, E2F-1
Anti-E2F1 Monoclonal Antibody
(3Z145)

| Description | Anti-E2F1 Monoclonal Antibody (3Z145) is a Mouse antibody targeting E2F1. Anti-E2F1 Monoclonal Antibody (3Z145) can be used in WB,IHC,FCM. |
| Synonyms | RBP3, RBBP3, RBAP1, E2F-1 |
| Ig Type | IgG1 |
| Clone | 3Z145 |
| Reactivity | Human,Mouse |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IHC: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F2 and E2F3, have an additional cyclin binding domain. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner. It can mediate both cell proliferation and p53-dependent/independent apoptosis. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human E2F1 (AA: 69-223) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | E2F1 |
| Gene ID | |
| Protein Name | Transcription factor E2F1 |
| Uniprot ID |
| Molecular Weight | Theoretical: 46.9 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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