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Synonyms: TCF-4, SEF-2, SEF2, PTHS, ITF-2, ITF2, FECD3, E2-2
Anti-TCF4 Monoclonal Antibody
(3A588)

| Description | Anti-TCF4 Monoclonal Antibody (3A588) is a Mouse antibody targeting TCF4. Anti-TCF4 Monoclonal Antibody (3A588) can be used in FCM. |
| Synonyms | TCF-4, SEF-2, SEF2, PTHS, ITF-2, ITF2, FECD3, E2-2 |
| Ig Type | IgG1 |
| Clone | 3A588 |
| Reactivity | Human |
| Application | |
| Recommended Dose | FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | This gene encodes transcription factor 4, a basic helix-loop-helix transcription factor. The encoded protein recognizes an Ephrussi-box ('E-box') binding site ('CANNTG') - a motif first identified in immunoglobulin enhancers. This gene is broadly expressed, and may play an important role in nervous system development. Defects in this gene are a cause of Pitt-Hopkins syndrome. In addition, an intronic CTG repeat normally numbering 10-37 repeat units can expand to >50 repeat units and cause Fuchs endothelial corneal dystrophy. Multiple alternatively spliced transcript variants that encode different proteins have been described. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human TCF4 (AA: 518-667) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | TCF4 |
| Gene ID | |
| Protein Name | Transcription factor 4 |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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