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Anti-DFFB Monoclonal Antibody (6H76)

(Synonyms: DFF-40, DFF40, DFF2, CPAN, CAD) Copy Product Info
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Synonyms: DFF-40, DFF40, DFF2, CPAN, CAD

Catalog No. TMAT-0497 Copy Product Info
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Anti-DFFB Monoclonal Antibody (6H76) is a Mouse antibody targeting DFFB. Anti-DFFB Monoclonal Antibody (6H76) can be used in IHC,IF,FCM.

Anti-DFFB Monoclonal Antibody
(6H76)

Pack SizePriceUSA StockGlobal StockQuantity
20 µLInquiry7-10 days7-10 days
50 µLInquiry7-10 days7-10 days
100 µLInquiry7-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-DFFB Monoclonal Antibody (6H76) is a Mouse antibody targeting DFFB. Anti-DFFB Monoclonal Antibody (6H76) can be used in IHC,IF,FCM.
SynonymsDFF-40, DFF40, DFF2, CPAN, CAD
Ig Type
IgG1
Clone
6H76
Reactivity
Human
Application
Recommended Dose
IHC: 1/200-1/1000; IF: 1/500-1/2000; FCM: 1/200-1/400
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationPurified by protein A or protein G
AppearanceLiquid
FormulationPBS with 0.05% sodium azide
Concentration1 mg/ml
Research BackgroundApoptosis is a cell death process that removes toxic and/or useless cells during mammalian development. The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal units. DNA fragmentation factor (DFF) is a heterodimeric protein of 40-kD (DFFB) and 45-kD (DFFA) subunits. DFFA is the substrate for caspase-3 and triggers DNA fragmentation during apoptosis. DFF becomes activated when DFFA is cleaved by caspase-3. The cleaved fragments of DFFA dissociate from DFFB, the active component of DFF. DFFB has been found to trigger both DNA fragmentation and chromatin condensation during apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene but the biological validity of some of these variants has not been determined. [provided by RefSeq, Sep 2013]
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Purified recombinant fragment of human DFFB (AA: 1-289) expressed in E. Coli.
Antigen Species
Human
Gene Name
DFFB
Gene ID
Protein Name
DNA fragmentation factor subunit beta
Uniprot ID
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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