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Synonyms: VICKZ3, KOC1, IMP-3, IMP3, IGF2BP3, DKFZp686F1078, CT98
Anti-IGF2BP3 Monoclonal Antibody
(8D402)

| Description | Anti-IGF2BP3 Monoclonal Antibody (8D402) is a Mouse antibody targeting IGF2BP3. Anti-IGF2BP3 Monoclonal Antibody (8D402) can be used in WB,IHC. |
| Synonyms | VICKZ3, KOC1, IMP-3, IMP3, IGF2BP3, DKFZp686F1078, CT98 |
| Ig Type | IgG1 |
| Clone | 8D402 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IHC: 1/200-1/1000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | Ascitic fluid containing 0.03% sodium azide |
| Concentration | 1 mg/ml |
| Research Background | The protein encoded by this gene is primarily found in the nucleolus, where it can bind to the 5' UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. The encoded protein contains several KH domains, which are important in RNA binding and are known to be involved in RNA synthesis and metabolism.Tissue specificity: Expressed in fetal liver, fetal lung, fetal kidney, fetal thymus, fetal placenta, fetal follicles of ovary and gonocytes of testis, growing oocytes, spermatogonia and semen (at protein level). Expressed in cervix adenocarcinoma, in testicular, pancreatic and renal-cell carcinomas (at protein level). Expressed ubiquitously during fetal development at 8 and 14 weeks of gestation. Expressed in ovary, testis, brain, placenta, pancreatic cancer tissues and pancreatic cancer cell lines .IMP-3 is a marker for carcinomas and high-grade dysplastic lesions of pancreatic ductal epithelium. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human IGF2BP3 expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | IGF2BP3 |
| Gene ID | |
| Protein Name | Insulin-like growth factor 2 mRNA-binding protein 3 |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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