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Anti-SIGLEC8 Monoclonal Antibody (5Z846)
(Synonyms: SIGLEC8L, SIGLEC-8, SAF2) Copy Product Info
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Synonyms: SIGLEC8L, SIGLEC-8, SAF2
Catalog No. TMAT-1595 Copy Product Info
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Anti-SIGLEC8 Monoclonal Antibody (5Z846) is a Mouse antibody targeting SIGLEC8. Anti-SIGLEC8 Monoclonal Antibody (5Z846) can be used in WB,IHC,FCM.
Anti-SIGLEC8 Monoclonal Antibody
(5Z846)
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Product Introduction
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| Description | Anti-SIGLEC8 Monoclonal Antibody (5Z846) is a Mouse antibody targeting SIGLEC8. Anti-SIGLEC8 Monoclonal Antibody (5Z846) can be used in WB,IHC,FCM. |
| Synonyms | SIGLEC8L, SIGLEC-8, SAF2 |
| Ig Type | IgG2b |
| Clone | 5Z846 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IHC: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | Sialic acid-binding immunoglobulin (Ig)-like lectins, or SIGLECs (e.g., CD33 (MIM 159590)), are a family of type 1 transmembrane proteins each having a unique expression pattern, mostly in hemopoietic cells. SIGLEC8 is a member of the CD33-like subgroup of SIGLECs, which are localized to 19q13.3-q13.4 and have 2 conserved cytoplasmic tyrosine-based motifs: an immunoreceptor tyrosine-based inhibitory motif, or ITIM (see MIM 604964), and a motif homologous to one identified in signaling lymphocyte activation molecule (SLAM; MIM 603492) that mediates an association with SLAM-associated protein (SAP; MIM 300490) (summarized by Foussias et al., 2000 [PubMed 11095983]) |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human SIGLEC8 (AA: extra 17-216) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | SIGLEC8 |
| Gene ID | |
| Protein Name | Sialic acid-binding Ig-like lectin 8 |
| Uniprot ID |
| Molecular Weight | Theoretical: 54 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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