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Anti-CD120B Monoclonal Antibody (2F73)

(Synonyms: TNFRSF1B, TNF-R-II, TNFR80, TNF-R75, TNFR2, TNFR1B, TNFBR, TBPII, p75TNFR, p75) Copy Product Info
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Synonyms: TNFRSF1B, TNF-R-II, TNFR80, TNF-R75, TNFR2, TNFR1B, TNFBR, TBPII, p75TNFR, p75

Catalog No. TMAT-0256 Copy Product Info
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Anti-CD120B Monoclonal Antibody (2F73) is a Mouse antibody targeting CD120B. Anti-CD120B Monoclonal Antibody (2F73) can be used in WB,FCM.

Anti-CD120B Monoclonal Antibody
(2F73)

Pack SizePriceUSA StockGlobal StockQuantity
20 µLInquiry7-10 days7-10 days
50 µLInquiry7-10 days7-10 days
100 µLInquiry7-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-CD120B Monoclonal Antibody (2F73) is a Mouse antibody targeting CD120B. Anti-CD120B Monoclonal Antibody (2F73) can be used in WB,FCM.
SynonymsTNFRSF1B, TNF-R-II, TNFR80, TNF-R75, TNFR2, TNFR1B, TNFBR, TBPII, p75TNFR, p75
Ig Type
IgG2b
Clone
2F73
Reactivity
Human,Mouse
Application
Recommended Dose
WB: 1/500-1/2000; FCM: 1/200-1/400
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationPurified by protein A or protein G
AppearanceLiquid
FormulationPBS with 0.05% sodium azide
Concentration1 mg/ml
Research BackgroundThe protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Purified recombinant fragment of human CD120B (AA: extra 23-257) expressed in E. Coli.
Antigen Species
Human
Gene Name
TNFRSF1B
Gene ID
Protein Name
Tumor necrosis factor receptor superfamily member 1B
Uniprot ID
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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