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Synonyms: TSLPR, CRLF2Y, CRL2
Anti-TSLPR Monoclonal Antibody
(8F405)

| Description | Anti-TSLPR Monoclonal Antibody (8F405) is a Mouse antibody targeting TSLPR. Anti-TSLPR Monoclonal Antibody (8F405) can be used in IHC,FCM. |
| Synonyms | TSLPR, CRLF2Y, CRL2 |
| Ig Type | IgG1 |
| Clone | 8F405 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IHC: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | This gene encodes a member of the type I cytokine receptor family. The encoded protein is a receptor for thymic stromal lymphopoietin (TSLP). Together with the interleukin 7 receptor (IL7R), the encoded protein and TSLP activate STAT3, STAT5, and JAK2 pathways, which control processes such as cell proliferation and development of the hematopoietic system. Rearrangement of this gene with immunoglobulin heavy chain gene (IGH) on chromosome 14, or with P2Y purinoceptor 8 gene (P2RY8) on the same X or Y chromosomes is associated with B-progenitor acute lymphoblastic leukemia (ALL) and Down syndrome ALL. Alternatively spliced transcript variants have been found for this gene. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human TSLPR (AA: extra(23-231)) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | CRLF2 |
| Gene ID | |
| Protein Name | Cytokine receptor-like factor 2 |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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