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Anti-TSLPR Monoclonal Antibody (8F405)

(Synonyms: TSLPR, CRLF2Y, CRL2) Copy Product Info
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Synonyms: TSLPR, CRLF2Y, CRL2

Catalog No. TMAT-1557 Copy Product Info
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Anti-TSLPR Monoclonal Antibody (8F405) is a Mouse antibody targeting TSLPR. Anti-TSLPR Monoclonal Antibody (8F405) can be used in IHC,FCM.

Anti-TSLPR Monoclonal Antibody
(8F405)

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Product Introduction

Bioactivity
Description
Anti-TSLPR Monoclonal Antibody (8F405) is a Mouse antibody targeting TSLPR. Anti-TSLPR Monoclonal Antibody (8F405) can be used in IHC,FCM.
SynonymsTSLPR, CRLF2Y, CRL2
Ig Type
IgG1
Clone
8F405
Reactivity
Human
Application
Recommended Dose
IHC: 1/200-1/1000; FCM: 1/200-1/400
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationPurified by protein A or protein G
AppearanceLiquid
FormulationPBS with 0.05% sodium azide
Concentration1 mg/mL
Research BackgroundThis gene encodes a member of the type I cytokine receptor family. The encoded protein is a receptor for thymic stromal lymphopoietin (TSLP). Together with the interleukin 7 receptor (IL7R), the encoded protein and TSLP activate STAT3, STAT5, and JAK2 pathways, which control processes such as cell proliferation and development of the hematopoietic system. Rearrangement of this gene with immunoglobulin heavy chain gene (IGH) on chromosome 14, or with P2Y purinoceptor 8 gene (P2RY8) on the same X or Y chromosomes is associated with B-progenitor acute lymphoblastic leukemia (ALL) and Down syndrome ALL. Alternatively spliced transcript variants have been found for this gene.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Purified recombinant fragment of human TSLPR (AA: extra(23-231)) expressed in E. Coli.
Antigen Species
Human
Gene Name
CRLF2
Gene ID
Protein Name
Cytokine receptor-like factor 2
Uniprot ID
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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