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HuGAL-F2
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Catalog No. T9901A-1300 Copy Product Info
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HuGAL-F2 is a humanized monoclonal antibody targeting human basic fibroblast growth factor (bFGF/FGF2). FGF2 is a critical factor in tumor angiogenesis, exerting its effects by binding to and activating FGFRs, which possess receptor tyrosine kinase activity. HuGAL-F2 functions by specifically binding to and neutralizing extracellular FGF2, blocking its interaction with FGFRs and directly inhibiting endothelial cell proliferation, migration, and tube formation mediated by this pathway. Featuring a huIgG2 heavy chain and a hu-kappa light chain, this antibody is a significant tool for researching solid tumor angiogenesis and tissue fibrosis.
HuGAL-F2
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $222 | Inquiry | Inquiry | |
| 5 mg | $698 | Inquiry | Inquiry | |
| 10 mg | $1,090 | Inquiry | Inquiry |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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| Description | HuGAL-F2 is a humanized monoclonal antibody targeting human basic fibroblast growth factor (bFGF/FGF2). FGF2 is a critical factor in tumor angiogenesis, exerting its effects by binding to and activating FGFRs, which possess receptor tyrosine kinase activity. HuGAL-F2 functions by specifically binding to and neutralizing extracellular FGF2, blocking its interaction with FGFRs and directly inhibiting endothelial cell proliferation, migration, and tube formation mediated by this pathway. Featuring a huIgG2 heavy chain and a hu-kappa light chain, this antibody is a significant tool for researching solid tumor angiogenesis and tissue fibrosis. |
| Reactivity | Human |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Uniprot ID | |
| Target | FGF2 |
| Isotype | IgG2SA |
| Storage | Store at low temperature Store at -20°C Shipping with blue ice/Shipping at ambient temperature. |
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