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Anti-RUNX1 Monoclonal Antibody (4S177)
(Synonyms: PEBP2alpha, PEBP2aB, EVI-1, CBFA2, CBF2alpha, AMLCR1, AML1-EVI-1, AML1) Copy Product Info
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Synonyms: PEBP2alpha, PEBP2aB, EVI-1, CBFA2, CBF2alpha, AMLCR1, AML1-EVI-1, AML1
Catalog No. TMAT-1190 Copy Product Info
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Anti-RUNX1 Monoclonal Antibody (4S177) is a Mouse antibody targeting RUNX1. Anti-RUNX1 Monoclonal Antibody (4S177) can be used in FCM.
Anti-RUNX1 Monoclonal Antibody
(4S177)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Stability & Storage
| Description | Anti-RUNX1 Monoclonal Antibody (4S177) is a Mouse antibody targeting RUNX1. Anti-RUNX1 Monoclonal Antibody (4S177) can be used in FCM. |
| Synonyms | PEBP2alpha, PEBP2aB, EVI-1, CBFA2, CBF2alpha, AMLCR1, AML1-EVI-1, AML1 |
| Ig Type | IgG1 |
| Clone | 4S177 |
| Reactivity | Human |
| Application | |
| Recommended Dose | FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human RUNX1 (AA: 237-337) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | RUNX1 |
| Gene ID | |
| Protein Name | Runt-related transcription factor 1 |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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