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Synonyms: P450PCN1, P450C3, NF-25, HLP, CYPIIIA4, CYPIIIA3, CYP3A3, CYP3A, CP34, CP33
Anti-CYP3A4 Monoclonal Antibody
(1V310)

| Description | Anti-CYP3A4 Monoclonal Antibody (1V310) is a Mouse antibody targeting CYP3A4. Anti-CYP3A4 Monoclonal Antibody (1V310) can be used in WB,IHC,IF,FCM. |
| Synonyms | P450PCN1, P450C3, NF-25, HLP, CYPIIIA4, CYPIIIA3, CYP3A3, CYP3A, CP34, CP33 |
| Ig Type | IgG1 |
| Clone | 1V310 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IHC: 1/100-1/500; IF: 1/50-1/500; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. This enzyme is involved in the metabolism of approximately half the drugs in use today, including acetaminophen, codeine, cyclosporin A, diazepam and erythromycin. The enzyme also metabolizes some steroids and carcinogens. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Previously another CYP3A gene, CYP3A3, was thought to exist; however, it is now thought that this sequence represents a transcript variant of CYP3A4. Alternatively spliced transcript variants encoding different isoforms have been identified. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human CYP3A4 expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | CYP3A4 |
| Gene ID | |
| Protein Name | Cytochrome P450 3A4 |
| Uniprot ID |
| Molecular Weight | Theoretical: 57.3 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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