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Anti-CYP3A4 Monoclonal Antibody (1V310)

(Synonyms: P450PCN1, P450C3, NF-25, HLP, CYPIIIA4, CYPIIIA3, CYP3A3, CYP3A, CP34, CP33) Copy Product Info
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Synonyms: P450PCN1, P450C3, NF-25, HLP, CYPIIIA4, CYPIIIA3, CYP3A3, CYP3A, CP34, CP33

Catalog No. TMAT-0767 Copy Product Info
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Anti-CYP3A4 Monoclonal Antibody (1V310) is a Mouse antibody targeting CYP3A4. Anti-CYP3A4 Monoclonal Antibody (1V310) can be used in WB,IHC,IF,FCM.

Anti-CYP3A4 Monoclonal Antibody
(1V310)

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Product Introduction

Bioactivity
Description
Anti-CYP3A4 Monoclonal Antibody (1V310) is a Mouse antibody targeting CYP3A4. Anti-CYP3A4 Monoclonal Antibody (1V310) can be used in WB,IHC,IF,FCM.
SynonymsP450PCN1, P450C3, NF-25, HLP, CYPIIIA4, CYPIIIA3, CYP3A3, CYP3A, CP34, CP33
Ig Type
IgG1
Clone
1V310
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1/500-1/2000; IHC: 1/100-1/500; IF: 1/50-1/500; FCM: 1/200-1/400
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationPurified by protein A or protein G
AppearanceLiquid
FormulationPBS with 0.05% sodium azide
Concentration1 mg/mL
Research BackgroundThis gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. This enzyme is involved in the metabolism of approximately half the drugs in use today, including acetaminophen, codeine, cyclosporin A, diazepam and erythromycin. The enzyme also metabolizes some steroids and carcinogens. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Previously another CYP3A gene, CYP3A3, was thought to exist; however, it is now thought that this sequence represents a transcript variant of CYP3A4. Alternatively spliced transcript variants encoding different isoforms have been identified.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Purified recombinant fragment of human CYP3A4 expressed in E. Coli.
Antigen Species
Human
Gene Name
CYP3A4
Gene ID
Protein Name
Cytochrome P450 3A4
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 57.3 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: Anti-CYP3A4 Monoclonal Antibody (1V310) molecular weight