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Anti-Cyclooxygenase 2 Antibody (8F987)
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Catalog No. TMAB-04851
Anti-Cyclooxygenase 2 Antibody (8F987) is a Mouse antibody targeting Cyclooxygenase 2. Anti-Cyclooxygenase 2 Antibody (8F987) can be used in WB.
Anti-Cyclooxygenase 2 Antibody (8F987)
Anti-Cyclooxygenase 2 Antibody (8F987)
😃Good
Catalog No. TMAB-04851
Anti-Cyclooxygenase 2 Antibody (8F987) is a Mouse antibody targeting Cyclooxygenase 2. Anti-Cyclooxygenase 2 Antibody (8F987) can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $223 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Cyclooxygenase 2 Antibody (8F987) is a Mouse antibody targeting Cyclooxygenase 2. Anti-Cyclooxygenase 2 Antibody (8F987) can be used in WB. |
| Ig Type | IgG1, k |
| Clone | 8F987 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Subcellular Localization | Microsome membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Peripheral membrane protein. Post-translational modifications : S-nitrosylation by NOS2 (iNOS) activates enzme activity. S-nitrosylation may take place on different Cys residues in addition to Cys-561. |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Protein G purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis. [provided by RefSeq, Feb 2009] |
| Immunogen | Recombinant Protein: human PTGS2 |
| Antigen Species | Human |
| Gene Name | Ptgs2 |
| Gene ID | |
| Protein Name | Prostaglandin G/H synthase 2 |
| Uniprot ID | |
| Function | Mediates the formation of prostaglandins from arachidonate. May have a role as a major mediator of inflammation and/or a role for prostanoid signaling in activity-dependent plasticity. |
| Molecular Weight | Theoretical: 65 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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