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Anti-CD222 Monoclonal Antibody (4K86)
(Synonyms: MPRI, MPR300, MPR1, M6P-R, M6P/IGF2R, IGF2R, CIMPR, CI-M6PR) Copy Product Info
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Synonyms: MPRI, MPR300, MPR1, M6P-R, M6P/IGF2R, IGF2R, CIMPR, CI-M6PR
Catalog No. TMAT-0331 Copy Product Info
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Anti-CD222 Monoclonal Antibody (4K86) is a Mouse antibody targeting CD222. Anti-CD222 Monoclonal Antibody (4K86) can be used in FCM.
Anti-CD222 Monoclonal Antibody
(4K86)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Stability & Storage
| Description | Anti-CD222 Monoclonal Antibody (4K86) is a Mouse antibody targeting CD222. Anti-CD222 Monoclonal Antibody (4K86) can be used in FCM. |
| Synonyms | MPRI, MPR300, MPR1, M6P-R, M6P/IGF2R, IGF2R, CIMPR, CI-M6PR |
| Ig Type | IgG1 |
| Clone | 4K86 |
| Reactivity | Human |
| Application | |
| Recommended Dose | FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/ml |
| Research Background | This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate. The binding sites for each ligand are located on different segments of the protein. This receptor has various functions, including in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. Mutation or loss of heterozygosity of this gene has been association with risk of hepatocellular carcinoma. The orthologous mouse gene is imprinted and shows exclusive expression from the maternal allele; however, imprinting of the human gene may be polymorphic, as only a minority of individuals showed biased expression from the maternal allele (PMID:8267611). [provided by RefSeq, Nov 2015] |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human CD222 (AA: 160-311) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | IGF2R |
| Gene ID | |
| Protein Name | Cation-independent mannose-6-phosphate receptor |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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