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Anti-DAXX Monoclonal Antibody (2F950)
(Synonyms: EAP1, DAP6, BING2) Copy Product Info
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Synonyms: EAP1, DAP6, BING2
Catalog No. TMAT-1609 Copy Product Info
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Anti-DAXX Monoclonal Antibody (2F950) is a Mouse antibody targeting DAXX. Anti-DAXX Monoclonal Antibody (2F950) can be used in WB,IF,FCM.
Anti-DAXX Monoclonal Antibody
(2F950)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
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Chemical Properties
Stability & Storage
| Description | Anti-DAXX Monoclonal Antibody (2F950) is a Mouse antibody targeting DAXX. Anti-DAXX Monoclonal Antibody (2F950) can be used in WB,IF,FCM. |
| Synonyms | EAP1, DAP6, BING2 |
| Ig Type | IgG1 |
| Clone | 2F950 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IF: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide. |
| Concentration | 1 mg/mL |
| Research Background | DAXX (death-domain associated protein), it is a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human DAXX expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | DAXX |
| Gene ID | |
| Protein Name | Death domain-associated protein 6 |
| Uniprot ID |
| Molecular Weight | Theoretical: 81 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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